Predicted Trait | |
Reported Trait | Physical activity (self-reported) |
Mapped Trait(s) | |
Additional Trait Information | UK Biobank Data-Field 884 |
Score Construction | |
PGS Name | PRS_reported |
Development Method | |
Name | LDpred |
Parameters | HapMap3 variants, MAF > 5%, excluding MHC region (GRCh37: 6p22.1–21.3) |
Variants | |
Original Genome Build | GRCh37 |
Number of Variants | 1,142,416 |
Effect Weight Type | beta |
PGS Source | |
PGS Catalog Publication (PGP) ID | PGP000280 |
Citation (link to publication) | Kujala UM et al. Med Sci Sports Exerc (2020) |
Ancestry Distribution | |
Source of Variant Associations (GWAS) | European: 100% 321,309 individuals (100%) |
PGS Evaluation | European: 100% 2 Sample Sets |
Study Identifiers | Sample Numbers | Sample Ancestry | Cohort(s) |
---|---|---|---|
— | 321,309 individuals | European | UKB |
PGS Performance Metric ID (PPM) |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
---|---|---|---|---|---|---|---|---|
PPM012823 | PSS009569| European Ancestry| 11,528 individuals |
PGP000280 | Kujala UM et al. Med Sci Sports Exerc (2020) |
Reported Trait: Daily leisure-time physical activity (MET score) | β: 0.1717 (0.0323) | — | ΔR2 (%): 0.25 | age, sex, and four genetic principal components | — |
PPM012824 | PSS009571| European Ancestry| 4,061 individuals |
PGP000280 | Kujala UM et al. Med Sci Sports Exerc (2020) |
Reported Trait: Daily leisure-time physical activity (MET score) | β: 0.0355 (0.0113) | — | ΔR2 (%): 0.24 | age, sex, and four genetic principal components | — |
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
---|---|---|---|---|---|---|---|---|
PSS009569 | — | — | 11,528 individuals, 46.0 % Male samples |
Mean = 44.0 years | European (Finnish) |
— | FTC | — |
PSS009571 | — | — | 4,061 individuals, 48.0 % Male samples |
Mean = 46.0 years | European (Finnish) |
— | NFBC | — |