|
PGS Publication/Study ID (PGP) |
PGS Developed |
PGS Evaluated |
First Author | Title | Journal Name |
Publication Date |
Digital object identifier (doi) |
PubMed ID (PMID) |
|---|---|---|---|---|---|---|---|---|
| PGP000740 | 1 | 1 | Hu J | Robust pleiotropy-decomposed polygenic scores identify distinct contributions to elevated coronary artery disease polygenic risk. | PLoS Comput Biol | 26/06/2025 | 10.1371/journal.pcbi.1013191 | 40570042 |
| PGP000743 | 3 | 3 | Ismail Umlai UK | A multi-ancestry genome-wide association study and evaluation of polygenic scores of LDL-C levels. | J Lipid Res | 03/02/2025 | 10.1016/j.jlr.2025.100752 | 39909172 |
| PGP000735 | 9 | 9 | Foote IF | Uncovering the multivariate genetic architecture of frailty with genomic structural equation modeling | Nat Genet | 24/07/2024 | 10.1038/s41588-025-02269-0 | — |
| PGP000724 | 7 | 7 | Smit RAJ | Polygenic prediction of body mass index and obesity through the life course and across ancestries. | Nat Med | 21/07/2025 | 10.1038/s41591-025-03827-z | 40691366 |
| Polygenic Score ID & Name | PGS Publication ID (PGP) | Reported Trait | Mapped Trait(s) (Ontology) | Number of Variants |
Ancestry distribution GWAS Dev Eval |
Scoring File (FTP Link) |
|---|---|---|---|---|---|---|
| PGS005198 (GIANT_BMI_2025_PRSCS) |
PGP000724 | Smit RAJ et al. Nat Med (2025) |
Body mass index (BMI) | body mass index | 1,217,710 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005198/ScoringFiles/PGS005198.txt.gz |
| PGS005199 (G23_BMI_2025_PRSCSx_META) |
PGP000724 | Smit RAJ et al. Nat Med (2025) |
Body mass index (BMI) | body mass index | 1,296,245 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005199/ScoringFiles/PGS005199.txt.gz |
| PGS005200 (G23_BMI_2025_PRSCSx_LC_AFR) |
PGP000724 | Smit RAJ et al. Nat Med (2025) |
Body mass index (BMI) | body mass index | 1,223,921 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005200/ScoringFiles/PGS005200.txt.gz | |
| PGS005201 (G23_BMI_2025_PRSCSx_LC_AMR) |
PGP000724 | Smit RAJ et al. Nat Med (2025) |
Body mass index (BMI) | body mass index | 1,020,295 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005201/ScoringFiles/PGS005201.txt.gz | |
| PGS005202 (G23_BMI_2025_PRSCSx_LC_EAS) |
PGP000724 | Smit RAJ et al. Nat Med (2025) |
Body mass index (BMI) | body mass index | 1,022,487 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005202/ScoringFiles/PGS005202.txt.gz | |
| PGS005203 (G23_BMI_2025_PRSCSx_LC_EUR) |
PGP000724 | Smit RAJ et al. Nat Med (2025) |
Body mass index (BMI) | body mass index | 1,091,375 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005203/ScoringFiles/PGS005203.txt.gz | |
| PGS005204 (G23_BMI_2025_PRSCSx_LC_SAS) |
PGP000724 | Smit RAJ et al. Nat Med (2025) |
Body mass index (BMI) | body mass index | 1,129,666 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005204/ScoringFiles/PGS005204.txt.gz | |
| PGS005221 (General_Frailty) |
PGP000735 | Foote IF et al. Nat Genet (2024) |
General factor of frailty | frailty measurement | 943,126 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005221/ScoringFiles/PGS005221.txt.gz |
| PGS005222 (F1_Frailty) |
PGP000735 | Foote IF et al. Nat Genet (2024) |
Factor 1 (social isolation) of frailty | frailty measurement | 1,727,299 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005222/ScoringFiles/PGS005222.txt.gz |
| PGS005223 (F2_Frailty) |
PGP000735 | Foote IF et al. Nat Genet (2024) |
Factor 2 (unhealthy lifestyle) of frailty | frailty measurement | 1,719,220 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005223/ScoringFiles/PGS005223.txt.gz |
| PGS005224 (F3_Frailty) |
PGP000735 | Foote IF et al. Nat Genet (2024) |
Factor 3 (multimorbidity) of frailty | frailty measurement | 1,588,232 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005224/ScoringFiles/PGS005224.txt.gz |
| PGS005225 (F4_Frailty) |
PGP000735 | Foote IF et al. Nat Genet (2024) |
Factor 4 (metabolic/respiratory problems) of frailty | frailty measurement | 710,413 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005225/ScoringFiles/PGS005225.txt.gz |
| PGS005226 (F5_Frailty) |
PGP000735 | Foote IF et al. Nat Genet (2024) |
Factor 5 (poorer cognition) of frailty | frailty measurement | 1,715,891 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005226/ScoringFiles/PGS005226.txt.gz |
| PGS005227 (F6_Frailty) |
PGP000735 | Foote IF et al. Nat Genet (2024) |
Factor 6 (disability) of frailty | frailty measurement | 1,726,064 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005227/ScoringFiles/PGS005227.txt.gz |
| PGS005228 (FI_Frailty) |
PGP000735 | Foote IF et al. Nat Genet (2024) |
Frailty Index | frailty measurement | 2,379,429 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005228/ScoringFiles/PGS005228.txt.gz |
| PGS005229 (FFS_Frailty) |
PGP000735 | Foote IF et al. Nat Genet (2024) |
Fried Frailty Score | frailty measurement | 2,761,868 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005229/ScoringFiles/PGS005229.txt.gz |
| PGS005236 (CAD_AnnoPred) |
PGP000740 | Hu J et al. PLoS Comput Biol (2025) |
Coronary artery disease | coronary artery disease | 2,994,055 | https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005236/ScoringFiles/PGS005236.txt.gz | |
| PGS005248 (PGS4_QBB_9SNP) |
PGP000743 | Ismail Umlai UK et al. J Lipid Res (2025) |
LDL-C levels | low density lipoprotein cholesterol measurement | 9 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005248/ScoringFiles/PGS005248.txt.gz |
| PGS005249 (PGS5_QBB_6SNP) |
PGP000743 | Ismail Umlai UK et al. J Lipid Res (2025) |
LDL-C levels | low density lipoprotein cholesterol measurement | 6 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005249/ScoringFiles/PGS005249.txt.gz |
| PGS005250 (PGS14_QBB_14SNP) |
PGP000743 | Ismail Umlai UK et al. J Lipid Res (2025) |
LDL-C levels | low density lipoprotein cholesterol measurement | 14 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS005250/ScoringFiles/PGS005250.txt.gz |