| Phenotype | Cases were defined on the presence or absence of severe insulin deficiency (requiring insulin treatment at 3 years after diagnosis). We cate- gorized people as severely insulin defi- cient if they received continuous insulin treatment at ,3 years from the time of diagnosis and had a low measured C-peptide level (nonfasting measured ,0.6 nmol/L or equivalent fasting blood glucose level or posthome meal urine C-peptide–to–creatinine ratio) |
| Sample Ancestry | European |
| Total number | 223 individuals |
| Detailed numbers |
46 cases (20.63%)
177 controls
46.3% Male samples
|
| Number of Cohort(s) | 1 |
Cohort Short Name
|
Cohort Full Name
|
Previous/other/additional names (e.g. sub-cohorts)
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|---|---|---|
| P2ID | Progression to Insulin Deficiency: South West England Cohort | — |
A cross-sectional cohort of people in whom diabetes was diagnosed between the ages of 20 and 40 years (n = 223), who had had diabetes for .3 years, and who had self-reported as white European from Devon and Cornwall in South West England. Known monogenic diabetes and secondary diabetes pa- tients were excluded.