PGS Sample Set (PSS): PSS011313

Phenotype To define prevalent CAD, we selected participants with ICD-10 codes for MI (I21.X, I22.X, I23.X, I24.1, or I25.2), for other acute ischemic heart disease (I24.0, I24.8-9) and for atherosclerotic / chronic ischemic heart disease (I25.0-25.1, I25.5-25.9). Procedure codes for coronary artery bypass grafting (K40.1-40.4, K41.1-41.4, K45.1-45.5), for coronary angioplasty, with or without stenting (K49.1-49.2, K49.8-49.9, K50.2, K75.1-75.4, K75.8-75.9) were also added to the CAD definition.
Sample Ancestry European (White British)

Sample Numbers

Total number
403,422 individuals
Detailed numbers
32,475 cases (8.05%)
370,947 controls
46.0% Male samples
Participant Follow-up Time Mean : 11.0 years
Age of Study Participants Mean : 56.93 years
Number of Cohort(s) 1
Sample distribution
ControlsCases
Sample gender distribution
% Female% Male

Cohort(s)

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Cohort Short Name
Cohort Full Name
Previous/other/additional names (e.g. sub-cohorts)
UKBUK Biobank
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