Phenotype | A participant was defined as a CAD case if he/she had at least one occurrence of International Classification of Diseases, 10th edition (ICD-10) codes I21-I25 (covering ischemic heart diseases) or at least one occurrence of the following codes in Office of Population Censuses and Surveys Classification of Interventions and Procedures, version 4 (OPCS-4): K40- K46, K49, K50 or K75, which include replacement, transluminal balloon angioplasty, and other therapeutic transluminal operations on coronary artery, and percutaneous transluminal balloon angioplasty and insertion of stents. Death because of CAD was defined as an occurrence of any of the ICD-10 codes stated above as the primary cause of death. Primary incident CAD events were either captured on the earliest date of CAD event/CAD death after enrollment, or censored at the end of HES-based follow-up or at time of competing death, whichever occurred first. Those who have had CAD diagnosis before enrollment were excluded from the incident CAD analysis. 10358 CAD cases were prevalent and 9847 were incident. |
Sample Ancestry | European |
Total number | 307,151 individuals |
Detailed numbers |
9,847 cases (3.21%)
297,304 controls
46.1% Male samples
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Participant Follow-up Time | Median : [0.0, 8.4] years |
Age of Study Participants |
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Number of Cohort(s) | 1 |
Cohort Short Name
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Cohort Full Name
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Previous/other/additional names (e.g. sub-cohorts)
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UKB | UK Biobank | — |