PGS Sample Set (PSS): PSS011727

Phenotype A participant was defined as a CAD case if he/she had at least one occurrence of International Classification of Diseases, 10th edition (ICD-10) codes I21-I25 (covering ischemic heart diseases) or at least one occurrence of the following codes in Office of Population Censuses and Surveys Classification of Interventions and Procedures, version 4 (OPCS-4): K40- K46, K49, K50 or K75, which include replacement, transluminal balloon angioplasty, and other therapeutic transluminal operations on coronary artery, and percutaneous transluminal balloon angioplasty and insertion of stents. Death because of CAD was defined as an occurrence of any of the ICD-10 codes stated above as the primary cause of death. Primary incident CAD events were either captured on the earliest date of CAD event/CAD death after enrollment, or censored at the end of HES-based follow-up or at time of competing death, whichever occurred first. Those who have had CAD diagnosis before enrollment were excluded from the incident CAD analysis. 10358 CAD cases were prevalent and 9847 were incident.
Sample Ancestry European

Sample Numbers

Total number
307,151 individuals
Detailed numbers
9,847 cases (3.21%)
297,304 controls
46.1% Male samples
Participant Follow-up Time Median : [0.0, 8.4] years
Age of Study Participants
  • Mean : 57.4 years
  • Sd : 8.0 years
Number of Cohort(s) 1
Sample distribution
ControlsCases
Sample gender distribution
% Female% Male

Cohort(s)

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Cohort Short Name
Cohort Full Name
Previous/other/additional names (e.g. sub-cohorts)
UKBUK Biobank
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