Predicted Trait | |
Reported Trait | Immature fraction of reticulocytes |
Mapped Trait(s) | reticulocyte count (EFO_0007986) |
Additional Trait Information | IRF |
Score Construction | |
PGS Name | irf |
Development Method | |
Name | Genome-wide significant variants |
Parameters | Conditionally independent GWAS associations |
Variants | |
Original Genome Build | GRCh37 |
Number of Variants | 372 |
Effect Weight Type | beta |
PGS Source | |
PGS Catalog Publication (PGP) ID | PGP000078 |
Citation (link to publication) | Vuckovic D et al. Cell (2020) |
Ancestry Distribution | |
Source of Variant Associations (GWAS) | European: 100% 408,112 individuals (100%) |
PGS Evaluation | European: 100% 1 Sample Sets |
Study Identifiers | Sample Numbers | Sample Ancestry | Cohort(s) |
---|---|---|---|
Europe PMC: 10.1101/2020.02.02.20020065 |
408,112 individuals | European | UKB |
PGS Performance Metric ID (PPM) |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
---|---|---|---|---|---|---|---|---|
PPM000527 | PSS000291| European Ancestry| 39,260 individuals |
PGP000078 | Vuckovic D et al. Cell (2020) |
Reported Trait: Immature fraction of reticulocytes | — | — | R²: 0.09164 | sex, age, 10 genetic PCs | — |
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
---|---|---|---|---|---|---|---|---|
PSS000291 | — | — | 39,260 individuals | — | European | — | INTERVAL | — |