Polygenic Score (PGS) ID: PGS000173

Predicted Trait
Reported Trait Lymphocyte percentage of white cells
Mapped Trait(s) lymphocyte percentage of leukocytes (EFO_0007993)
Additional Trait Information LYMPH%
Released in PGS Catalog: April 29, 2020
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Score Details

Score Construction
PGS Name lymph_p
Development Method
Name Genome-wide significant variants
Parameters Conditionally independent GWAS associations
Variants
Original Genome Build GRCh37
Number of Variants 472
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000078
Citation (link to publication) Vuckovic D et al. Cell (2020)
Ancestry Distribution
Source of Variant
Associations (GWAS)
European: 100%
408,112 individuals (100%)
PGS Evaluation
European: 100%
1 Sample Sets

Development Samples

Source of Variant Associations (GWAS)
Study Identifiers Sample Numbers Sample Ancestry Cohort(s)
408,112 individuals European UKB

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM000529 PSS000291|
European Ancestry|
39,260 individuals
 PGP000078 |
Vuckovic D et al. Cell (2020)
 Reported Trait: Lymphocyte percentage of white cells — — R²: 0.06965 sex, age, 10 genetic PCs —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS000291 — — 39,260 individuals — European — INTERVAL —