| Predicted Trait | |
| Reported Trait | Sleep duration |
| Mapped Trait(s) | sleep duration trait (OBA_2040171) |
| Additional Trait Information | https://biobankengine.stanford.edu/RIVAS_HG19/snpnet/INI1160 |
| Score Construction | |
| PGS Name | GBE_INI1160 |
| Development Method | |
| Name | snpnet |
| Parameters | NR |
| Variants | |
| Original Genome Build | GRCh37 |
| Number of Variants | 4,106 |
| Effect Weight Type | NR |
| PGS Source | |
| PGS Catalog Publication (PGP) ID | PGP000244 |
| Citation (link to publication) | Tanigawa Y et al. PLoS Genet (2022) |
| Ancestry Distribution | |
| Score Development/Training | European: 100% 268,353 individuals (100%) |
| PGS Evaluation | European: 40% African: 20% East Asian: 20% South Asian: 20% 5 Sample Sets |
Study Identifiers
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Sample Numbers
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Sample Ancestry
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Cohort(s)
|
Phenotype Definitions & Methods
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Age of Study Participants
|
Participant Follow-up Time
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Additional Ancestry Description
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Additional Sample/Cohort Information
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|---|---|---|---|---|---|---|---|---|
| — | 268,353 individuals | European | UKB | — | — | — | white British ancestry | — |
PGS Performance Metric ID (PPM) |
PGS Sample Set ID (PSS) |
Performance Source
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Trait
|
PGS Effect Sizes (per SD change) |
Classification Metrics
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Other Metrics
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Covariates Included in the Model
|
PGS Performance: Other Relevant Information |
|---|---|---|---|---|---|---|---|---|
| PPM008477 | PSS004796| African Ancestry| 6,246 individuals | PGP000244 | Tanigawa Y et al. PLoS Genet (2022) | Reported Trait: Sleep duration | — | — | R²: 0.01014 [0.0053, 0.01499] Incremental R2 (full-covars): 0.00154 PGS R2 (no covariates): 0.00168 [-0.00031, 0.00366] | age, sex, UKB array type, Genotype PCs | — |
| PPM008478 | PSS004797| East Asian Ancestry| 1,652 individuals | PGP000244 | Tanigawa Y et al. PLoS Genet (2022) | Reported Trait: Sleep duration | — | — | R²: 0.04058 [0.02227, 0.0589] Incremental R2 (full-covars): 0.00193 PGS R2 (no covariates): 0.00695 [-0.00089, 0.0148] | age, sex, UKB array type, Genotype PCs | — |
| PPM008479 | PSS004798| European Ancestry| 24,750 individuals | PGP000244 | Tanigawa Y et al. PLoS Genet (2022) | Reported Trait: Sleep duration | — | — | R²: 0.01244 [0.00971, 0.01518] Incremental R2 (full-covars): 0.00809 PGS R2 (no covariates): 0.00875 [0.00645, 0.01105] | age, sex, UKB array type, Genotype PCs | — |
| PPM008480 | PSS004799| South Asian Ancestry| 7,598 individuals | PGP000244 | Tanigawa Y et al. PLoS Genet (2022) | Reported Trait: Sleep duration | — | — | R²: 0.008 [0.00407, 0.01193] Incremental R2 (full-covars): 0.00387 PGS R2 (no covariates): 0.00403 [0.00123, 0.00683] | age, sex, UKB array type, Genotype PCs | — |
| PPM008481 | PSS004800| European Ancestry| 67,069 individuals | PGP000244 | Tanigawa Y et al. PLoS Genet (2022) | Reported Trait: Sleep duration | — | — | R²: 0.01307 [0.01137, 0.01477] Incremental R2 (full-covars): 0.00777 PGS R2 (no covariates): 0.00798 [0.00664, 0.00932] | age, sex, UKB array type, Genotype PCs | — |
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods
|
Participant Follow-up Time
|
Sample Numbers
|
Age of Study Participants
|
Sample Ancestry
|
Additional Ancestry Description
|
Cohort(s)
|
Additional Sample/Cohort Information
|
|---|---|---|---|---|---|---|---|---|
| PSS004796 | — | — | 6,246 individuals | — | African unspecified | — | UKB | — |
| PSS004797 | — | — | 1,652 individuals | — | East Asian | — | UKB | — |
| PSS004798 | — | — | 24,750 individuals | — | European | non-white British ancestry | UKB | — |
| PSS004799 | — | — | 7,598 individuals | — | South Asian | — | UKB | — |
| PSS004800 | — | — | 67,069 individuals | — | European | white British ancestry | UKB | Testing cohort (heldout set) |