Polygenic Score (PGS) ID: PGS001150

Predicted Trait
Reported Trait Sleep duration
Mapped Trait(s) sleep duration (EFO_0005271)
Additional Trait Information https://biobankengine.stanford.edu/RIVAS_HG19/snpnet/INI1160
Released in PGS Catalog: Oct. 21, 2021
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Terms and Licenses
PGS obtained from the Catalog should be cited appropriately, and used in accordance with any licensing restrictions set by the authors. See EBI Terms of Use (https://www.ebi.ac.uk/about/terms-of-use/) for additional details.

Score Details

Score Construction
PGS Name GBE_INI1160
Development Method
Name snpnet
Parameters NR
Variants
Original Genome Build GRCh37
Number of Variants 4,106
Effect Weight Type NR
PGS Source
PGS Catalog Publication (PGP) ID PGP000244
Citation (link to publication) Tanigawa Y et al. PLoS Genet (2022)
Ancestry Distribution
Score Development/Training
European: 100%
268,353 individuals (100%)
PGS Evaluation
European: 40%
African: 20%
East Asian: 20%
South Asian: 20%
5 Sample Sets

Development Samples

Score Development/Training
Study Identifiers Sample Numbers Sample Ancestry Cohort(s) Phenotype Definitions & Methods Age of Study Participants Participant Follow-up Time Additional Ancestry Description Additional Sample/Cohort Information
— 268,353 individuals European UKB — — — white British ancestry —

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM008477 PSS004796|
African Ancestry|
6,246 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Sleep duration — — R²: 0.01014 [0.0053, 0.01499]
Incremental R2 (full-covars): 0.00154
PGS R2 (no covariates): 0.00168 [-0.00031, 0.00366]		 age, sex, UKB array type, Genotype PCs —
PPM008478 PSS004797|
East Asian Ancestry|
1,652 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Sleep duration — — R²: 0.04058 [0.02227, 0.0589]
Incremental R2 (full-covars): 0.00193
PGS R2 (no covariates): 0.00695 [-0.00089, 0.0148]		 age, sex, UKB array type, Genotype PCs —
PPM008479 PSS004798|
European Ancestry|
24,750 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Sleep duration — — R²: 0.01244 [0.00971, 0.01518]
Incremental R2 (full-covars): 0.00809
PGS R2 (no covariates): 0.00875 [0.00645, 0.01105]		 age, sex, UKB array type, Genotype PCs —
PPM008480 PSS004799|
South Asian Ancestry|
7,598 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Sleep duration — — R²: 0.008 [0.00407, 0.01193]
Incremental R2 (full-covars): 0.00387
PGS R2 (no covariates): 0.00403 [0.00123, 0.00683]		 age, sex, UKB array type, Genotype PCs —
PPM008481 PSS004800|
European Ancestry|
67,069 individuals
 PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
 Reported Trait: Sleep duration — — R²: 0.01307 [0.01137, 0.01477]
Incremental R2 (full-covars): 0.00777
PGS R2 (no covariates): 0.00798 [0.00664, 0.00932]		 age, sex, UKB array type, Genotype PCs —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS004796 — — 6,246 individuals — African unspecified — UKB —
PSS004797 — — 1,652 individuals — East Asian — UKB —
PSS004798 — — 24,750 individuals — European non-white British ancestry UKB —
PSS004799 — — 7,598 individuals — South Asian — UKB —
PSS004800 — — 67,069 individuals — European white British ancestry UKB Testing cohort (heldout set)