| Predicted Trait | |
| Reported Trait | Impedance (left arm) |
| Mapped Trait(s) | body composition measurement (EFO_0005106) |
| Additional Trait Information | https://biobankengine.stanford.edu/RIVAS_HG19/snpnet/INI23110 |
| Score Construction | |
| PGS Name | GBE_INI23110 |
| Development Method | |
| Name | snpnet |
| Parameters | NR |
| Variants | |
| Original Genome Build | GRCh37 |
| Number of Variants | 26,740 |
| Effect Weight Type | NR |
| PGS Source | |
| PGS Catalog Publication (PGP) ID | PGP000244 |
| Citation (link to publication) | Tanigawa Y et al. PLoS Genet (2022) |
| Ancestry Distribution | |
| Score Development/Training | European: 100% 265,390 individuals (100%) |
| PGS Evaluation | European: 40% African: 20% East Asian: 20% South Asian: 20% 5 Sample Sets |
Study Identifiers
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Sample Numbers
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Sample Ancestry
|
Cohort(s)
|
Phenotype Definitions & Methods
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Age of Study Participants
|
Participant Follow-up Time
|
Additional Ancestry Description
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Additional Sample/Cohort Information
|
|---|---|---|---|---|---|---|---|---|
| — | 265,390 individuals | European | UKB | — | — | — | white British ancestry | — |
PGS Performance Metric ID (PPM) |
PGS Sample Set ID (PSS) |
Performance Source
|
Trait
|
PGS Effect Sizes (per SD change) |
Classification Metrics
|
Other Metrics
|
Covariates Included in the Model
|
PGS Performance: Other Relevant Information |
|---|---|---|---|---|---|---|---|---|
| PPM008492 | PSS005081| African Ancestry| 6,310 individuals | PGP000244 | Tanigawa Y et al. PLoS Genet (2022) | Reported Trait: Impedance of arm (L) | — | — | R²: 0.40184 [0.38341, 0.42027] Incremental R2 (full-covars): 0.00929 PGS R2 (no covariates): 0.01779 [0.01142, 0.02415] | age, sex, UKB array type, Genotype PCs | — |
| PPM008493 | PSS005082| East Asian Ancestry| 1,681 individuals | PGP000244 | Tanigawa Y et al. PLoS Genet (2022) | Reported Trait: Impedance of arm (L) | — | — | R²: 0.57437 [0.5438, 0.60494] Incremental R2 (full-covars): 0.01873 PGS R2 (no covariates): 0.01902 [0.0062, 0.03184] | age, sex, UKB array type, Genotype PCs | — |
| PPM008494 | PSS005083| European Ancestry| 24,474 individuals | PGP000244 | Tanigawa Y et al. PLoS Genet (2022) | Reported Trait: Impedance of arm (L) | — | — | R²: 0.57497 [0.56697, 0.58297] Incremental R2 (full-covars): 0.0528 PGS R2 (no covariates): 0.05187 [0.0465, 0.05723] | age, sex, UKB array type, Genotype PCs | — |
| PPM008495 | PSS005084| South Asian Ancestry| 7,653 individuals | PGP000244 | Tanigawa Y et al. PLoS Genet (2022) | Reported Trait: Impedance of arm (L) | — | — | R²: 0.53183 [0.51672, 0.54695] Incremental R2 (full-covars): 0.03819 PGS R2 (no covariates): 0.03481 [0.02684, 0.04279] | age, sex, UKB array type, Genotype PCs | — |
| PPM008496 | PSS005085| European Ancestry| 66,310 individuals | PGP000244 | Tanigawa Y et al. PLoS Genet (2022) | Reported Trait: Impedance of arm (L) | — | — | R²: 0.58392 [0.57912, 0.58872] Incremental R2 (full-covars): 0.05546 PGS R2 (no covariates): 0.05563 [0.05227, 0.05899] | age, sex, UKB array type, Genotype PCs | — |
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods
|
Participant Follow-up Time
|
Sample Numbers
|
Age of Study Participants
|
Sample Ancestry
|
Additional Ancestry Description
|
Cohort(s)
|
Additional Sample/Cohort Information
|
|---|---|---|---|---|---|---|---|---|
| PSS005081 | — | — | 6,310 individuals | — | African unspecified | — | UKB | — |
| PSS005082 | — | — | 1,681 individuals | — | East Asian | — | UKB | — |
| PSS005083 | — | — | 24,474 individuals | — | European | non-white British ancestry | UKB | — |
| PSS005084 | — | — | 7,653 individuals | — | South Asian | — | UKB | — |
| PSS005085 | — | — | 66,310 individuals | — | European | white British ancestry | UKB | Testing cohort (heldout set) |