Predicted Trait | |
Reported Trait | Impedance (right arm) |
Mapped Trait(s) | body composition measurement (EFO_0005106) |
Additional Trait Information | https://biobankengine.stanford.edu/RIVAS_HG19/snpnet/INI23109 |
Score Construction | |
PGS Name | GBE_INI23109 |
Development Method | |
Name | snpnet |
Parameters | NR |
Variants | |
Original Genome Build | GRCh37 |
Number of Variants | 30,140 |
Effect Weight Type | NR |
PGS Source | |
PGS Catalog Publication (PGP) ID | PGP000244 |
Citation (link to publication) | Tanigawa Y et al. PLoS Genet (2022) |
Ancestry Distribution | |
Score Development/Training | European: 100% 265,382 individuals (100%) |
PGS Evaluation | European: 40% African: 20% East Asian: 20% South Asian: 20% 5 Sample Sets |
Study Identifiers | Sample Numbers | Sample Ancestry | Cohort(s) | Phenotype Definitions & Methods | Age of Study Participants | Participant Follow-up Time | Additional Ancestry Description | Additional Sample/Cohort Information |
---|---|---|---|---|---|---|---|---|
— | 265,382 individuals | European | UKB | — | — | — | white British ancestry | — |
PGS Performance Metric ID (PPM) |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
---|---|---|---|---|---|---|---|---|
PPM008502 | PSS005076| African Ancestry| 6,310 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Impedance of arm (R) | — | — | R²: 0.39048 [0.37197, 0.40899] Incremental R2 (full-covars): 0.00926 PGS R2 (no covariates): 0.01716 [0.0109, 0.02342] |
age, sex, UKB array type, Genotype PCs | — |
PPM008503 | PSS005077| East Asian Ancestry| 1,681 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Impedance of arm (R) | — | — | R²: 0.54175 [0.50979, 0.57371] Incremental R2 (full-covars): 0.0153 PGS R2 (no covariates): 0.02132 [0.00778, 0.03486] |
age, sex, UKB array type, Genotype PCs | — |
PPM008504 | PSS005078| European Ancestry| 24,473 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Impedance of arm (R) | — | — | R²: 0.57975 [0.5718, 0.58769] Incremental R2 (full-covars): 0.05372 PGS R2 (no covariates): 0.0533 [0.04787, 0.05873] |
age, sex, UKB array type, Genotype PCs | — |
PPM008505 | PSS005079| South Asian Ancestry| 7,653 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Impedance of arm (R) | — | — | R²: 0.53386 [0.51878, 0.54894] Incremental R2 (full-covars): 0.03597 PGS R2 (no covariates): 0.03083 [0.02329, 0.03836] |
age, sex, UKB array type, Genotype PCs | — |
PPM008506 | PSS005080| European Ancestry| 66,307 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Impedance of arm (R) | — | — | R²: 0.57547 [0.57061, 0.58033] Incremental R2 (full-covars): 0.05379 PGS R2 (no covariates): 0.05414 [0.05082, 0.05746] |
age, sex, UKB array type, Genotype PCs | — |
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
---|---|---|---|---|---|---|---|---|
PSS005076 | — | — | 6,310 individuals | — | African unspecified | — | UKB | — |
PSS005077 | — | — | 1,681 individuals | — | East Asian | — | UKB | — |
PSS005078 | — | — | 24,473 individuals | — | European | non-white British ancestry | UKB | — |
PSS005079 | — | — | 7,653 individuals | — | South Asian | — | UKB | — |
PSS005080 | — | — | 66,307 individuals | — | European | white British ancestry | UKB | Testing cohort (heldout set) |