| Predicted Trait | |
| Reported Trait | Mean ICVF in anterior corona radiata on FA skeleton (L) |
| Mapped Trait(s) | |
| Additional Trait Information | https://biobankengine.stanford.edu/RIVAS_HG19/snpnet/INI25367 |
| Score Construction | |
| PGS Name | GBE_INI25367 |
| Development Method | |
| Name | snpnet |
| Parameters | NR |
| Variants | |
| Original Genome Build | GRCh37 |
| Number of Variants | 1,490 |
| Effect Weight Type | NR |
| PGS Source | |
| PGS Catalog Publication (PGP) ID | PGP000244 |
| Citation (link to publication) | Tanigawa Y et al. PLoS Genet (2022) |
| Ancestry Distribution | |
| Score Development/Training | European: 100% 21,080 individuals (100%) |
| PGS Evaluation | European: 40% African: 20% East Asian: 20% South Asian: 20% 5 Sample Sets |
Study Identifiers
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Sample Numbers
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Sample Ancestry
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Cohort(s)
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Phenotype Definitions & Methods
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Age of Study Participants
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Participant Follow-up Time
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Additional Ancestry Description
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Additional Sample/Cohort Information
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|---|---|---|---|---|---|---|---|---|
| — | 21,080 individuals | European | UKB | — | — | — | white British ancestry | Training + validation cohort (train_val) |
PGS Performance Metric ID (PPM) |
PGS Sample Set ID (PSS) |
Performance Source
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Trait
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PGS Effect Sizes (per SD change) |
Classification Metrics
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Other Metrics
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Covariates Included in the Model
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PGS Performance: Other Relevant Information |
|---|---|---|---|---|---|---|---|---|
| PPM005765 | PSS005601| African Ancestry| 182 individuals | PGP000244 | Tanigawa Y et al. PLoS Genet (2022) | Reported Trait: Mean ICVF in anterior corona radiata on FA skeleton (L) | — | — | R²: 0.10807 [0.09381, 0.12232] Incremental R2 (full-covars): -0.00728 PGS R2 (no covariates): 0.00178 [-0.00027, 0.00383] | age, sex, UKB array type, Genotype PCs | — |
| PPM005766 | PSS005602| East Asian Ancestry| 106 individuals | PGP000244 | Tanigawa Y et al. PLoS Genet (2022) | Reported Trait: Mean ICVF in anterior corona radiata on FA skeleton (L) | — | — | R²: 0.2029 [0.16888, 0.23693] Incremental R2 (full-covars): 0.0795 PGS R2 (no covariates): 0.09947 [0.07256, 0.12639] | age, sex, UKB array type, Genotype PCs | — |
| PPM005767 | PSS005603| European Ancestry| 1,651 individuals | PGP000244 | Tanigawa Y et al. PLoS Genet (2022) | Reported Trait: Mean ICVF in anterior corona radiata on FA skeleton (L) | — | — | R²: 0.20755 [0.19858, 0.21652] Incremental R2 (full-covars): 0.03447 PGS R2 (no covariates): 0.03244 [0.02811, 0.03677] | age, sex, UKB array type, Genotype PCs | — |
| PPM005768 | PSS005604| South Asian Ancestry| 299 individuals | PGP000244 | Tanigawa Y et al. PLoS Genet (2022) | Reported Trait: Mean ICVF in anterior corona radiata on FA skeleton (L) | — | — | R²: 0.11129 [0.09816, 0.12442] Incremental R2 (full-covars): 0.01082 PGS R2 (no covariates): 0.01404 [0.00887, 0.01922] | age, sex, UKB array type, Genotype PCs | — |
| PPM005769 | PSS005605| European Ancestry| 5,120 individuals | PGP000244 | Tanigawa Y et al. PLoS Genet (2022) | Reported Trait: Mean ICVF in anterior corona radiata on FA skeleton (L) | — | — | R²: 0.17758 [0.17235, 0.18281] Incremental R2 (full-covars): 0.04438 PGS R2 (no covariates): 0.04394 [0.04091, 0.04697] | age, sex, UKB array type, Genotype PCs | — |
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods
|
Participant Follow-up Time
|
Sample Numbers
|
Age of Study Participants
|
Sample Ancestry
|
Additional Ancestry Description
|
Cohort(s)
|
Additional Sample/Cohort Information
|
|---|---|---|---|---|---|---|---|---|
| PSS005601 | — | — | 182 individuals | — | African unspecified | — | UKB | — |
| PSS005602 | — | — | 106 individuals | — | East Asian | — | UKB | — |
| PSS005603 | — | — | 1,651 individuals | — | European | non-white British ancestry | UKB | — |
| PSS005604 | — | — | 299 individuals | — | South Asian | — | UKB | — |
| PSS005605 | — | — | 5,120 individuals | — | European | white British ancestry | UKB | Testing cohort (heldout set) |