| Predicted Trait | |
| Reported Trait | Mean ISOVF in anterior corona radiata on FA skeleton (R) |
| Mapped Trait(s) | |
| Additional Trait Information | https://biobankengine.stanford.edu/RIVAS_HG19/snpnet/INI25462 |
| Score Construction | |
| PGS Name | GBE_INI25462 |
| Development Method | |
| Name | snpnet |
| Parameters | NR |
| Variants | |
| Original Genome Build | GRCh37 |
| Number of Variants | 116 |
| Effect Weight Type | NR |
| PGS Source | |
| PGS Catalog Publication (PGP) ID | PGP000244 |
| Citation (link to publication) | Tanigawa Y et al. PLoS Genet (2022) |
| Ancestry Distribution | |
| Score Development/Training | European: 100% 21,080 individuals (100%) |
| PGS Evaluation | European: 40% African: 20% East Asian: 20% South Asian: 20% 5 Sample Sets |
| Study Identifiers | Sample Numbers | Sample Ancestry | Cohort(s) | Phenotype Definitions & Methods | Age of Study Participants | Participant Follow-up Time | Additional Ancestry Description | Additional Sample/Cohort Information |
|---|---|---|---|---|---|---|---|---|
| — | 21,080 individuals | European | UKB | — | — | — | white British ancestry | Training + validation cohort (train_val) |
|
PGS Performance Metric ID (PPM) |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
|---|---|---|---|---|---|---|---|---|
| PPM005900 | PSS005736| African Ancestry| 182 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Mean ISOVF in anterior corona radiata on FA skeleton (R) | — | — | R²: 0.13983 [0.1242, 0.15547] Incremental R2 (full-covars): 0.00433 PGS R2 (no covariates): 0.00602 [0.00227, 0.00977] |
age, sex, UKB array type, Genotype PCs | — |
| PPM005901 | PSS005737| East Asian Ancestry| 106 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Mean ISOVF in anterior corona radiata on FA skeleton (R) | — | — | R²: 0.05202 [0.03153, 0.07251] Incremental R2 (full-covars): -0.00746 PGS R2 (no covariates): 0.00155 [-0.00218, 0.00528] |
age, sex, UKB array type, Genotype PCs | — |
| PPM005902 | PSS005738| European Ancestry| 1,651 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Mean ISOVF in anterior corona radiata on FA skeleton (R) | — | — | R²: 0.03973 [0.03498, 0.04449] Incremental R2 (full-covars): 0.00713 PGS R2 (no covariates): 0.00907 [0.00673, 0.01141] |
age, sex, UKB array type, Genotype PCs | — |
| PPM005903 | PSS005739| South Asian Ancestry| 299 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Mean ISOVF in anterior corona radiata on FA skeleton (R) | — | — | R²: 0.03415 [0.02625, 0.04206] Incremental R2 (full-covars): -0.00293 PGS R2 (no covariates): 0.0001 [-0.00034, 0.00055] |
age, sex, UKB array type, Genotype PCs | — |
| PPM005904 | PSS005740| European Ancestry| 5,120 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Mean ISOVF in anterior corona radiata on FA skeleton (R) | — | — | R²: 0.03569 [0.03294, 0.03844] Incremental R2 (full-covars): 0.00938 PGS R2 (no covariates): 0.01112 [0.00954, 0.01269] |
age, sex, UKB array type, Genotype PCs | — |
|
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
|---|---|---|---|---|---|---|---|---|
| PSS005736 | — | — | 182 individuals | — | African unspecified | — | UKB | — |
| PSS005737 | — | — | 106 individuals | — | East Asian | — | UKB | — |
| PSS005738 | — | — | 1,651 individuals | — | European | non-white British ancestry | UKB | — |
| PSS005739 | — | — | 299 individuals | — | South Asian | — | UKB | — |
| PSS005740 | — | — | 5,120 individuals | — | European | white British ancestry | UKB | Testing cohort (heldout set) |