| Predicted Trait | |
| Reported Trait | Mean ISOVF in superior corona radiata on FA skeleton (R) |
| Mapped Trait(s) | |
| Additional Trait Information | https://biobankengine.stanford.edu/RIVAS_HG19/snpnet/INI25464 |
| Score Construction | |
| PGS Name | GBE_INI25464 |
| Development Method | |
| Name | snpnet |
| Parameters | NR |
| Variants | |
| Original Genome Build | GRCh37 |
| Number of Variants | 392 |
| Effect Weight Type | NR |
| PGS Source | |
| PGS Catalog Publication (PGP) ID | PGP000244 |
| Citation (link to publication) | Tanigawa Y et al. PLoS Genet (2022) |
| Ancestry Distribution | |
| Score Development/Training | European: 100% 21,080 individuals (100%) |
| PGS Evaluation | European: 40% African: 20% East Asian: 20% South Asian: 20% 5 Sample Sets |
| Study Identifiers | Sample Numbers | Sample Ancestry | Cohort(s) | Phenotype Definitions & Methods | Age of Study Participants | Participant Follow-up Time | Additional Ancestry Description | Additional Sample/Cohort Information |
|---|---|---|---|---|---|---|---|---|
| — | 21,080 individuals | European | UKB | — | — | — | white British ancestry | Training + validation cohort (train_val) |
|
PGS Performance Metric ID (PPM) |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
|---|---|---|---|---|---|---|---|---|
| PPM005910 | PSS005746| African Ancestry| 182 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Mean ISOVF in superior corona radiata on FA skeleton (R) | — | — | R²: 0.14119 [0.12551, 0.15688] Incremental R2 (full-covars): 0.00823 PGS R2 (no covariates): 0.00543 [0.00186, 0.00899] |
age, sex, UKB array type, Genotype PCs | — |
| PPM005911 | PSS005747| East Asian Ancestry| 106 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Mean ISOVF in superior corona radiata on FA skeleton (R) | — | — | R²: 0.15533 [0.12378, 0.18688] Incremental R2 (full-covars): 0.00903 PGS R2 (no covariates): 0.00957 [0.00039, 0.01875] |
age, sex, UKB array type, Genotype PCs | — |
| PPM005912 | PSS005748| European Ancestry| 1,651 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Mean ISOVF in superior corona radiata on FA skeleton (R) | — | — | R²: 0.08802 [0.0813, 0.09474] Incremental R2 (full-covars): 0.00364 PGS R2 (no covariates): 0.00356 [0.00208, 0.00503] |
age, sex, UKB array type, Genotype PCs | — |
| PPM005913 | PSS005749| South Asian Ancestry| 299 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Mean ISOVF in superior corona radiata on FA skeleton (R) | — | — | R²: 0.09075 [0.07862, 0.10287] Incremental R2 (full-covars): -0.00021 PGS R2 (no covariates): 0.00022 [-0.00044, 0.00087] |
age, sex, UKB array type, Genotype PCs | — |
| PPM005914 | PSS005750| European Ancestry| 5,120 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Mean ISOVF in superior corona radiata on FA skeleton (R) | — | — | R²: 0.10032 [0.09602, 0.10462] Incremental R2 (full-covars): 0.00337 PGS R2 (no covariates): 0.00417 [0.0032, 0.00514] |
age, sex, UKB array type, Genotype PCs | — |
|
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
|---|---|---|---|---|---|---|---|---|
| PSS005746 | — | — | 182 individuals | — | African unspecified | — | UKB | — |
| PSS005747 | — | — | 106 individuals | — | East Asian | — | UKB | — |
| PSS005748 | — | — | 1,651 individuals | — | European | non-white British ancestry | UKB | — |
| PSS005749 | — | — | 299 individuals | — | South Asian | — | UKB | — |
| PSS005750 | — | — | 5,120 individuals | — | European | white British ancestry | UKB | Testing cohort (heldout set) |