Predicted Trait | |
Reported Trait | Volume of grey matter in Temporal Pole (R) |
Mapped Trait(s) | |
Additional Trait Information | https://biobankengine.stanford.edu/RIVAS_HG19/snpnet/INI25797 |
Score Construction | |
PGS Name | GBE_INI25797 |
Development Method | |
Name | snpnet |
Parameters | NR |
Variants | |
Original Genome Build | GRCh37 |
Number of Variants | 1,025 |
Effect Weight Type | NR |
PGS Source | |
PGS Catalog Publication (PGP) ID | PGP000244 |
Citation (link to publication) | Tanigawa Y et al. PLoS Genet (2022) |
Ancestry Distribution | |
Score Development/Training | European: 100% 22,320 individuals (100%) |
PGS Evaluation | European: 40% African: 20% East Asian: 20% South Asian: 20% 5 Sample Sets |
Study Identifiers
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Sample Numbers
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Sample Ancestry
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Cohort(s)
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Phenotype Definitions & Methods
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Age of Study Participants
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Participant Follow-up Time
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Additional Ancestry Description
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Additional Sample/Cohort Information
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— | 22,320 individuals | European | UKB | — | — | — | white British ancestry | Training + validation cohort (train_val) |
PGS Performance Metric ID (PPM) |
PGS Sample Set ID (PSS) |
Performance Source
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Trait
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PGS Effect Sizes (per SD change) |
Classification Metrics
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Other Metrics
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Covariates Included in the Model
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PGS Performance: Other Relevant Information |
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PPM006660 | PSS006496| African Ancestry| 200 individuals | PGP000244 | Tanigawa Y et al. PLoS Genet (2022) | Reported Trait: Vol. of grey matter in Temporal Pole (R) | — | — | R²: 0.29367 [0.27506, 0.31227] Incremental R2 (full-covars): -0.0006 PGS R2 (no covariates): 0.00034 [-0.00055, 0.00123] | age, sex, UKB array type, Genotype PCs | — |
PPM006661 | PSS006497| East Asian Ancestry| 113 individuals | PGP000244 | Tanigawa Y et al. PLoS Genet (2022) | Reported Trait: Vol. of grey matter in Temporal Pole (R) | — | — | R²: 0.27711 [0.24105, 0.31318] Incremental R2 (full-covars): -0.00498 PGS R2 (no covariates): 0.00265 [-0.00222, 0.00751] | age, sex, UKB array type, Genotype PCs | — |
PPM006662 | PSS006498| European Ancestry| 1,739 individuals | PGP000244 | Tanigawa Y et al. PLoS Genet (2022) | Reported Trait: Vol. of grey matter in Temporal Pole (R) | — | — | R²: 0.18563 [0.17692, 0.19434] Incremental R2 (full-covars): 0.00586 PGS R2 (no covariates): 0.00421 [0.0026, 0.00581] | age, sex, UKB array type, Genotype PCs | — |
PPM006663 | PSS006499| South Asian Ancestry| 329 individuals | PGP000244 | Tanigawa Y et al. PLoS Genet (2022) | Reported Trait: Vol. of grey matter in Temporal Pole (R) | — | — | R²: 0.20415 [0.18823, 0.22007] Incremental R2 (full-covars): 0.00593 PGS R2 (no covariates): 0.00289 [0.00052, 0.00526] | age, sex, UKB array type, Genotype PCs | — |
PPM006664 | PSS006500| European Ancestry| 5,443 individuals | PGP000244 | Tanigawa Y et al. PLoS Genet (2022) | Reported Trait: Vol. of grey matter in Temporal Pole (R) | — | — | R²: 0.18629 [0.18099, 0.19159] Incremental R2 (full-covars): 0.00858 PGS R2 (no covariates): 0.00866 [0.00726, 0.01005] | age, sex, UKB array type, Genotype PCs | — |
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods
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Participant Follow-up Time
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Sample Numbers
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Age of Study Participants
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Sample Ancestry
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Additional Ancestry Description
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Cohort(s)
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Additional Sample/Cohort Information
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PSS006496 | — | — | 200 individuals | — | African unspecified | — | UKB | — |
PSS006497 | — | — | 113 individuals | — | East Asian | — | UKB | — |
PSS006498 | — | — | 1,739 individuals | — | European | non-white British ancestry | UKB | — |
PSS006499 | — | — | 329 individuals | — | South Asian | — | UKB | — |
PSS006500 | — | — | 5,443 individuals | — | European | white British ancestry | UKB | Testing cohort (heldout set) |