| Predicted Trait | |
| Reported Trait | WA MO in tract medial lemniscus (R) |
| Mapped Trait(s) | |
| Additional Trait Information | https://biobankengine.stanford.edu/RIVAS_HG19/snpnet/INI25560 |
| Score Construction | |
| PGS Name | GBE_INI25560 |
| Development Method | |
| Name | snpnet |
| Parameters | NR |
| Variants | |
| Original Genome Build | GRCh37 |
| Number of Variants | 258 |
| Effect Weight Type | NR |
| PGS Source | |
| PGS Catalog Publication (PGP) ID | PGP000244 |
| Citation (link to publication) | Tanigawa Y et al. PLoS Genet (2022) |
| Ancestry Distribution | |
| Score Development/Training | European: 100% 21,081 individuals (100%) |
| PGS Evaluation | European: 40% African: 20% East Asian: 20% South Asian: 20% 5 Sample Sets |
Study Identifiers
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Sample Numbers
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Sample Ancestry
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Cohort(s)
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Phenotype Definitions & Methods
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Age of Study Participants
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Participant Follow-up Time
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Additional Ancestry Description
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Additional Sample/Cohort Information
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|---|---|---|---|---|---|---|---|---|
| — | 21,081 individuals | European | UKB | — | — | — | white British ancestry | Training + validation cohort (train_val) |
PGS Performance Metric ID (PPM) |
PGS Sample Set ID (PSS) |
Performance Source
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Trait
|
PGS Effect Sizes (per SD change) |
Classification Metrics
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Other Metrics
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Covariates Included in the Model
|
PGS Performance: Other Relevant Information |
|---|---|---|---|---|---|---|---|---|
| PPM006130 | PSS005966| African Ancestry| 182 individuals | PGP000244 | Tanigawa Y et al. PLoS Genet (2022) | Reported Trait: WA MO in tract medial lemniscus (R) | — | — | R²: 0.14902 [0.13305, 0.16499] Incremental R2 (full-covars): 0.00554 PGS R2 (no covariates): 0.00404 [0.00096, 0.00712] | age, sex, UKB array type, Genotype PCs | — |
| PPM006131 | PSS005967| East Asian Ancestry| 106 individuals | PGP000244 | Tanigawa Y et al. PLoS Genet (2022) | Reported Trait: WA MO in tract medial lemniscus (R) | — | — | R²: 0.1167 [0.08811, 0.1453] Incremental R2 (full-covars): -0.01758 PGS R2 (no covariates): 0.03109 [0.0149, 0.04728] | age, sex, UKB array type, Genotype PCs | — |
| PPM006132 | PSS005968| European Ancestry| 1,651 individuals | PGP000244 | Tanigawa Y et al. PLoS Genet (2022) | Reported Trait: WA MO in tract medial lemniscus (R) | — | — | R²: 0.0238 [0.02006, 0.02754] Incremental R2 (full-covars): 0.00381 PGS R2 (no covariates): 0.00494 [0.0032, 0.00668] | age, sex, UKB array type, Genotype PCs | — |
| PPM006133 | PSS005969| South Asian Ancestry| 299 individuals | PGP000244 | Tanigawa Y et al. PLoS Genet (2022) | Reported Trait: WA MO in tract medial lemniscus (R) | — | — | R²: 0.08227 [0.07062, 0.09393] Incremental R2 (full-covars): 0.00049 PGS R2 (no covariates): 0.0012 [-0.00033, 0.00274] | age, sex, UKB array type, Genotype PCs | — |
| PPM006134 | PSS005970| European Ancestry| 5,120 individuals | PGP000244 | Tanigawa Y et al. PLoS Genet (2022) | Reported Trait: WA MO in tract medial lemniscus (R) | — | — | R²: 0.02187 [0.01969, 0.02405] Incremental R2 (full-covars): 0.00403 PGS R2 (no covariates): 0.00456 [0.00354, 0.00557] | age, sex, UKB array type, Genotype PCs | — |
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods
|
Participant Follow-up Time
|
Sample Numbers
|
Age of Study Participants
|
Sample Ancestry
|
Additional Ancestry Description
|
Cohort(s)
|
Additional Sample/Cohort Information
|
|---|---|---|---|---|---|---|---|---|
| PSS005966 | — | — | 182 individuals | — | African unspecified | — | UKB | — |
| PSS005967 | — | — | 106 individuals | — | East Asian | — | UKB | — |
| PSS005968 | — | — | 1,651 individuals | — | European | non-white British ancestry | UKB | — |
| PSS005969 | — | — | 299 individuals | — | South Asian | — | UKB | — |
| PSS005970 | — | — | 5,120 individuals | — | European | white British ancestry | UKB | Testing cohort (heldout set) |