PGS Catalog - PGS001929 / Standing height (Polygenic Score)

Polygenic Score (PGS) ID: PGS001929

Predicted Trait
Reported Trait	Standing height
Mapped Trait(s)	body height (OBA_VT0001253)
Additional Trait Information	physical measures

Released in PGS Catalog: Jan. 10, 2022

Download Score FTP directory

Terms and Licenses

PGS obtained from the Catalog should be cited appropriately, and used in accordance with any licensing restrictions set by the authors. See EBI Terms of Use (https://www.ebi.ac.uk/about/terms-of-use/) for additional details.

Score Details

Score Construction
PGS Name	portability-PLR_height
Development Method
Name	Penalized regression (bigstatsr)
Parameters	HapMap3 variants
Variants
Original Genome Build	GRCh37
Number of Variants	156,514
Effect Weight Type	beta

PGS Source
PGS Catalog Publication (PGP) ID	PGP000263
Citation (link to publication)	Privé F et al. Am J Hum Genet (2022)

Ancestry Distribution
Score Development/Training	European: 100% 391,124 individuals (100%)
PGS Evaluation	European: 37.5% African: 25% East Asian: 12.5% Greater Middle Eastern: 12.5% South Asian: 12.5% 8 Sample Sets

Development Samples

Score Development/Training

Loading, please wait

Study Identifiers	Sample Numbers	Sample Ancestry	Cohort(s)	Phenotype Definitions & Methods	Age of Study Participants	Participant Follow-up Time	Additional Ancestry Description	Additional Sample/Cohort Information
—	391,124 individuals	European	UKB	—	—	—	UK (+ Ireland)	—

Showing 1 to 1 of 1 rows

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

Loading, please wait

PGS Performance Metric ID (PPM)	PGS Sample Set ID (PSS)	Performance Source	Trait	PGS Effect Sizes (per SD change)	Classification Metrics	Other Metrics	Covariates Included in the Model	PGS Performance: Other Relevant Information
PPM010307	PSS009416\| European Ancestry\| 19,953 individuals	PGP000263 \| Privé F et al. Am J Hum Genet (2022)	Reported Trait: Standing height	—	—	Partial Correlation (partial-r): 0.6344 [0.626, 0.6426]	sex, age, birth date, deprivation index, 16 PCs	—
PPM010308	PSS009190\| European Ancestry\| 4,126 individuals	PGP000263 \| Privé F et al. Am J Hum Genet (2022)	Reported Trait: Standing height	—	—	Partial Correlation (partial-r): 0.6098 [0.5902, 0.6286]	sex, age, birth date, deprivation index, 16 PCs	—
PPM010309	PSS008744\| European Ancestry\| 6,633 individuals	PGP000263 \| Privé F et al. Am J Hum Genet (2022)	Reported Trait: Standing height	—	—	Partial Correlation (partial-r): 0.5938 [0.578, 0.6092]	sex, age, birth date, deprivation index, 16 PCs	—
PPM010310	PSS008518\| Greater Middle Eastern Ancestry\| 1,180 individuals	PGP000263 \| Privé F et al. Am J Hum Genet (2022)	Reported Trait: Standing height	—	—	Partial Correlation (partial-r): 0.5167 [0.4732, 0.5576]	sex, age, birth date, deprivation index, 16 PCs	—
PPM010311	PSS008296\| South Asian Ancestry\| 6,152 individuals	PGP000263 \| Privé F et al. Am J Hum Genet (2022)	Reported Trait: Standing height	—	—	Partial Correlation (partial-r): 0.4923 [0.4731, 0.511]	sex, age, birth date, deprivation index, 16 PCs	—
PPM010312	PSS008073\| East Asian Ancestry\| 1,801 individuals	PGP000263 \| Privé F et al. Am J Hum Genet (2022)	Reported Trait: Standing height	—	—	Partial Correlation (partial-r): 0.4504 [0.4125, 0.4866]	sex, age, birth date, deprivation index, 16 PCs	—
PPM010313	PSS007860\| African Ancestry\| 2,450 individuals	PGP000263 \| Privé F et al. Am J Hum Genet (2022)	Reported Trait: Standing height	—	—	Partial Correlation (partial-r): 0.3454 [0.3099, 0.3799]	sex, age, birth date, deprivation index, 16 PCs	—
PPM010314	PSS008964\| African Ancestry\| 3,863 individuals	PGP000263 \| Privé F et al. Am J Hum Genet (2022)	Reported Trait: Standing height	—	—	Partial Correlation (partial-r): 0.2731 [0.2436, 0.3021]	sex, age, birth date, deprivation index, 16 PCs	—

Showing 1 to 8 of 8 rows

Evaluated Samples

Loading, please wait

PGS Sample Set ID (PSS)	Phenotype Definitions and Methods	Participant Follow-up Time	Sample Numbers	Age of Study Participants	Sample Ancestry	Additional Ancestry Description	Cohort(s)	Additional Sample/Cohort Information
PSS007860	—	—	2,450 individuals	—	African American or Afro-Caribbean	Carribean	UKB	—
PSS008073	—	—	1,801 individuals	—	East Asian	China (East Asia)	UKB	—
PSS008296	—	—	6,152 individuals	—	South Asian	India (South Asia)	UKB	—
PSS008518	—	—	1,180 individuals	—	Greater Middle Eastern (Middle Eastern, North African or Persian)	Iran (Middle East)	UKB	—
PSS008744	—	—	6,633 individuals	—	European	Italy (South Europe)	UKB	—
PSS008964	—	—	3,863 individuals	—	African unspecified	Nigeria (West Africa)	UKB	—
PSS009190	—	—	4,126 individuals	—	European	Poland (NE Europe)	UKB	—
PSS009416	—	—	19,953 individuals	—	European	UK (+ Ireland)	UKB	—

Showing 1 to 8 of 8 rows