PGS Catalog - PGS001931 / Average total household income before tax (Polygenic Score)

Polygenic Score (PGS) ID: PGS001931

Predicted Trait
Reported Trait	Average total household income before tax
Mapped Trait(s)	household income (EFO_0009695)
Additional Trait Information	lifestyle and environment

Released in PGS Catalog: Jan. 10, 2022

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PGS obtained from the Catalog should be cited appropriately, and used in accordance with any licensing restrictions set by the authors. See EBI Terms of Use (https://www.ebi.ac.uk/about/terms-of-use/) for additional details.

Score Details

Score Construction
PGS Name	portability-PLR_income
Development Method
Name	Penalized regression (bigstatsr)
Parameters	HapMap3 variants
Variants
Original Genome Build	GRCh37
Number of Variants	41,836
Effect Weight Type	beta

PGS Source
PGS Catalog Publication (PGP) ID	PGP000263
Citation (link to publication)	Privé F et al. Am J Hum Genet (2022)

Ancestry Distribution
Score Development/Training	European: 100% 391,124 individuals (100%)
PGS Evaluation	European: 37.5% African: 25% East Asian: 12.5% Greater Middle Eastern: 12.5% South Asian: 12.5% 8 Sample Sets

Development Samples

Score Development/Training

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Study Identifiers	Sample Numbers	Sample Ancestry	Cohort(s)	Phenotype Definitions & Methods	Age of Study Participants	Participant Follow-up Time	Additional Ancestry Description	Additional Sample/Cohort Information
—	391,124 individuals	European	UKB	—	—	—	UK (+ Ireland)	—

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Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

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PGS Performance Metric ID (PPM)	PGS Sample Set ID (PSS)	Performance Source	Trait	PGS Effect Sizes (per SD change)	Classification Metrics	Other Metrics	Covariates Included in the Model	PGS Performance: Other Relevant Information
PPM010323	PSS009418\| European Ancestry\| 17,147 individuals	PGP000263 \| Privé F et al. Am J Hum Genet (2022)	Reported Trait: Average total household income before tax	—	—	Partial Correlation (partial-r): 0.1409 [0.1262, 0.1556]	sex, age, birth date, deprivation index, 16 PCs	—
PPM010324	PSS009192\| European Ancestry\| 3,467 individuals	PGP000263 \| Privé F et al. Am J Hum Genet (2022)	Reported Trait: Average total household income before tax	—	—	Partial Correlation (partial-r): 0.0935 [0.0603, 0.1265]	sex, age, birth date, deprivation index, 16 PCs	—
PPM010325	PSS008746\| European Ancestry\| 5,619 individuals	PGP000263 \| Privé F et al. Am J Hum Genet (2022)	Reported Trait: Average total household income before tax	—	—	Partial Correlation (partial-r): 0.1334 [0.1076, 0.159]	sex, age, birth date, deprivation index, 16 PCs	—
PPM010326	PSS008520\| Greater Middle Eastern Ancestry\| 809 individuals	PGP000263 \| Privé F et al. Am J Hum Genet (2022)	Reported Trait: Average total household income before tax	—	—	Partial Correlation (partial-r): 0.0857 [0.016, 0.1546]	sex, age, birth date, deprivation index, 16 PCs	—
PPM010327	PSS008298\| South Asian Ancestry\| 4,548 individuals	PGP000263 \| Privé F et al. Am J Hum Genet (2022)	Reported Trait: Average total household income before tax	—	—	Partial Correlation (partial-r): 0.0826 [0.0536, 0.1114]	sex, age, birth date, deprivation index, 16 PCs	—
PPM010328	PSS008075\| East Asian Ancestry\| 1,404 individuals	PGP000263 \| Privé F et al. Am J Hum Genet (2022)	Reported Trait: Average total household income before tax	—	—	Partial Correlation (partial-r): 0.0367 [-0.016, 0.0892]	sex, age, birth date, deprivation index, 16 PCs	—
PPM010329	PSS007862\| African Ancestry\| 1,874 individuals	PGP000263 \| Privé F et al. Am J Hum Genet (2022)	Reported Trait: Average total household income before tax	—	—	Partial Correlation (partial-r): -0.0034 [-0.0489, 0.0422]	sex, age, birth date, deprivation index, 16 PCs	—
PPM010330	PSS008966\| African Ancestry\| 2,881 individuals	PGP000263 \| Privé F et al. Am J Hum Genet (2022)	Reported Trait: Average total household income before tax	—	—	Partial Correlation (partial-r): 0.0395 [0.0028, 0.076]	sex, age, birth date, deprivation index, 16 PCs	—

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Evaluated Samples

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PGS Sample Set ID (PSS)	Phenotype Definitions and Methods	Participant Follow-up Time	Sample Numbers	Age of Study Participants	Sample Ancestry	Additional Ancestry Description	Cohort(s)	Additional Sample/Cohort Information
PSS007862	—	—	1,874 individuals	—	African American or Afro-Caribbean	Carribean	UKB	—
PSS008075	—	—	1,404 individuals	—	East Asian	China (East Asia)	UKB	—
PSS008298	—	—	4,548 individuals	—	South Asian	India (South Asia)	UKB	—
PSS008520	—	—	809 individuals	—	Greater Middle Eastern (Middle Eastern, North African or Persian)	Iran (Middle East)	UKB	—
PSS008746	—	—	5,619 individuals	—	European	Italy (South Europe)	UKB	—
PSS008966	—	—	2,881 individuals	—	African unspecified	Nigeria (West Africa)	UKB	—
PSS009192	—	—	3,467 individuals	—	European	Poland (NE Europe)	UKB	—
PSS009418	—	—	17,147 individuals	—	European	UK (+ Ireland)	UKB	—

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