Polygenic Score (PGS) ID: PGS001961

Predicted Trait
Reported Trait Impedance of whole body
Mapped Trait(s) body composition measurement (EFO_0005106)
Additional Trait Information physical measures
Released in PGS Catalog: Jan. 10, 2022
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PGS obtained from the Catalog should be cited appropriately, and used in accordance with any licensing restrictions set by the authors. See EBI Terms of Use (https://www.ebi.ac.uk/about/terms-of-use/) for additional details.

Score Details

Score Construction
PGS Name portability-PLR_log_impedance
Development Method
Name Penalized regression (bigstatsr)
Parameters HapMap3 variants
Variants
Original Genome Build GRCh37
Number of Variants 119,500
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000263
Citation (link to publication) Privé F et al. Am J Hum Genet (2022)
Ancestry Distribution
Score Development/Training
European: 100%
391,124 individuals (100%)
PGS Evaluation
European: 37.5%
African: 25%
East Asian: 12.5%
Greater Middle Eastern: 12.5%
South Asian: 12.5%
8 Sample Sets

Development Samples

Score Development/Training
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Study Identifiers
Sample Numbers
Sample Ancestry
Cohort(s)
Phenotype Definitions & Methods
Age of Study Participants
Participant Follow-up Time
Additional Ancestry Description
Additional Sample/Cohort Information
391,124 individualsEuropeanUKBUK (+ Ireland)
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Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

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PGS Performance
Metric ID (PPM)
PGS Sample Set ID
(PSS)
Performance Source
Trait
PGS Effect Sizes
(per SD change)
Classification Metrics
Other Metrics
Covariates Included in the Model
PGS Performance:
Other Relevant Information
PPM010563PSS009450|
European Ancestry|
19,624 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Impedance of whole bodyPartial Correlation (partial-r): 0.4099 [0.3982, 0.4215]sex, age, birth date, deprivation index, 16 PCs
PPM010564PSS009224|
European Ancestry|
4,069 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Impedance of whole bodyPartial Correlation (partial-r): 0.4104 [0.3845, 0.4357]sex, age, birth date, deprivation index, 16 PCs
PPM010565PSS008778|
European Ancestry|
6,535 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Impedance of whole bodyPartial Correlation (partial-r): 0.3868 [0.366, 0.4073]sex, age, birth date, deprivation index, 16 PCs
PPM010566PSS008552|
Greater Middle Eastern Ancestry|
1,151 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Impedance of whole bodyPartial Correlation (partial-r): 0.4087 [0.359, 0.4561]sex, age, birth date, deprivation index, 16 PCs
PPM010567PSS008330|
South Asian Ancestry|
6,178 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Impedance of whole bodyPartial Correlation (partial-r): 0.366 [0.3441, 0.3874]sex, age, birth date, deprivation index, 16 PCs
PPM010568PSS008107|
East Asian Ancestry|
1,782 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Impedance of whole bodyPartial Correlation (partial-r): 0.2675 [0.2236, 0.3104]sex, age, birth date, deprivation index, 16 PCs
PPM010569PSS007894|
African Ancestry|
2,417 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Impedance of whole bodyPartial Correlation (partial-r): 0.229 [0.1907, 0.2666]sex, age, birth date, deprivation index, 16 PCs
PPM010570PSS008998|
African Ancestry|
3,798 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Impedance of whole bodyPartial Correlation (partial-r): 0.1708 [0.1397, 0.2016]sex, age, birth date, deprivation index, 16 PCs
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Evaluated Samples

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PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods
Participant Follow-up Time
Sample Numbers
Age of Study Participants
Sample Ancestry
Additional Ancestry Description
Cohort(s)
Additional Sample/Cohort Information
PSS0078942,417 individualsAfrican American or Afro-CaribbeanCarribeanUKB
PSS0081071,782 individualsEast AsianChina (East Asia)UKB
PSS0083306,178 individualsSouth AsianIndia (South Asia)UKB
PSS0085521,151 individualsGreater Middle Eastern (Middle Eastern, North African or Persian)Iran (Middle East)UKB
PSS0087786,535 individualsEuropeanItaly (South Europe)UKB
PSS0089983,798 individualsAfrican unspecifiedNigeria (West Africa)UKB
PSS0092244,069 individualsEuropeanPoland (NE Europe)UKB
PSS00945019,624 individualsEuropeanUK (+ Ireland)UKB
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