Polygenic Score (PGS) ID: PGS002440

Predicted Trait
Reported Trait College education
Mapped Trait(s) educational attainment (EFO_0011015)
Released in PGS Catalog: June 9, 2022
Download Score FTP directory
Terms and Licenses
PGS obtained from the Catalog should be cited appropriately, and used in accordance with any licensing restrictions set by the authors. See EBI Terms of Use (https://www.ebi.ac.uk/about/terms-of-use/) for additional details.

Score Details

Score Construction
PGS Name cov_EDU_COLLEGE.P+T.0.001
Development Method
Name Pruning and Thresholding (P+T)
Parameters p < 0.001
Variants
Original Genome Build GRCh37
Number of Variants 24,405
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000332
Citation (link to publication) Weissbrod O et al. Nat Genet (2022)
Ancestry Distribution
Source of Variant
Associations (GWAS)
European: 100%
334,353 individuals (100%)
PGS Evaluation
African: 25%
East Asian: 25%
European: 25%
South Asian: 25%
4 Sample Sets

Development Samples

Source of Variant Associations (GWAS)
Study Identifiers Sample Numbers Sample Ancestry Cohort(s)
— 334,353 individuals European UKB

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM013568 PSS009719|
African Ancestry|
6,277 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: College education — — Incremental R2 (full model vs. covariates alone): 0.0001 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013617 PSS009720|
East Asian Ancestry|
876 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: College education — — Incremental R2 (full model vs. covariates alone): 0.0 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013666 PSS009721|
European Ancestry|
42,914 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: College education — — Incremental R2 (full model vs. covariates alone): 0.0245 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013715 PSS009722|
South Asian Ancestry|
7,658 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: College education — — Incremental R2 (full model vs. covariates alone): 0.0036 age, sex, age*sex, assessment center, genotyping array, 10 PCs —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS009719 — — 6,277 individuals — African unspecified — UKB —
PSS009720 — — 876 individuals — East Asian — UKB —
PSS009721 — — 42,914 individuals — European Non-British European UKB —
PSS009722 — — 7,658 individuals — South Asian — UKB —