Predicted Trait | |
Reported Trait | Smoking status |
Mapped Trait(s) | smoking status measurement (EFO_0006527) |
Additional Trait Information | Smoking status: Current; Binary |
Score Construction | |
PGS Name | ExPRSweb_Smoking_20116-2_LASSOSUM_MGI_20211120 |
Development Method | |
Name | lassosum |
Parameters | Lassosum 0.4.4 (MAF >= 1%; autosomal variants only)s=0.9;Lambda=0.00264 |
Variants | |
Original Genome Build | GRCh37 |
Number of Variants | 515,021 |
Effect Weight Type | beta |
PGS Source | |
PGS Catalog Publication (PGP) ID | PGP000393 |
Citation (link to publication) | Ma Y et al. Am J Hum Genet (2022) |
Study Identifiers
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Sample Numbers
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Sample Ancestry
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Cohort(s)
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359,706 individuals | European | UKB |
Study Identifiers
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Sample Numbers
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Sample Ancestry
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Cohort(s)
|
Phenotype Definitions & Methods
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Age of Study Participants
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Participant Follow-up Time
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Additional Ancestry Description
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Additional Sample/Cohort Information
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---|---|---|---|---|---|---|---|---|
— | [
| European | MGI | never/past/current smoking status was recoded to never/ever responses.; Binary | — | — | — | — |
PGS Performance Metric ID (PPM) |
PGS Sample Set ID (PSS) |
Performance Source
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Trait
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PGS Effect Sizes (per SD change) |
Classification Metrics
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Other Metrics
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Covariates Included in the Model
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PGS Performance: Other Relevant Information |
---|---|---|---|---|---|---|---|---|
PPM015973 | PSS010013| European Ancestry| 23,332 individuals | PGP000393 | Ma Y et al. Am J Hum Genet (2022) | Reported Trait: Smoking Status | OR: 1.103 [1.071, 1.136] β: 0.0981 (0.0151) | AUROC: 0.527 [0.518, 0.535] | — | SEX,AGE,Batch,PC1,PC2,PC3,PC4 | — |
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods
|
Participant Follow-up Time
|
Sample Numbers
|
Age of Study Participants
|
Sample Ancestry
|
Additional Ancestry Description
|
Cohort(s)
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Additional Sample/Cohort Information
|
---|---|---|---|---|---|---|---|---|
PSS010013 | never/past/current smoking status was recoded to never/ever responses.; Binary | — | [
| — | European | — | MGI | — |