Polygenic Score (PGS) ID: PGS003401

Predicted Trait
Reported Trait Triglyceride levels
Mapped Trait(s) triglyceride measurement (EFO_0004530)
Released in PGS Catalog: Jan. 19, 2023
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Terms and Licenses
PGS obtained from the Catalog should be cited appropriately, and used in accordance with any licensing restrictions set by the authors. See EBI Terms of Use (https://www.ebi.ac.uk/about/terms-of-use/) for additional details.

Score Details

Score Construction
PGS Name TG.PS
Development Method
Name Genome-wide significant SNPs
Parameters r2 < 0.1
Variants
Original Genome Build NR
Number of Variants 108
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000418
Citation (link to publication) Pieri K et al. Int J Cardiol (2022)
Ancestry Distribution
Source of Variant
Associations (GWAS)
European: 100%
237,050 individuals (100%)
PGS Evaluation
European: 100%
2 Sample Sets

Development Samples

Source of Variant Associations (GWAS)
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Study Identifiers
Sample Numbers
Sample Ancestry
Cohort(s)
GWAS Catalog: GCST009149
Europe PMC: 29083408
237,050 individualsEuropeanNR
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Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

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PGS Performance
Metric ID (PPM)
PGS Sample Set ID
(PSS)
Performance Source
Trait
PGS Effect Sizes
(per SD change)
Classification Metrics
Other Metrics
Covariates Included in the Model
PGS Performance:
Other Relevant Information
PPM017030PSS010100|
European Ancestry|
460,037 individuals
PGP000418 |
Pieri K et al. Int J Cardiol (2022)
Reported Trait: Plasma triglyceride concentrationβ: 0.142 (0.000753)—% change in TG (per SD PGS): 15.2 [15.0, 15.4]——
PPM017031PSS010099|
European Ancestry|
6,952 individuals
PGP000418 |
Pieri K et al. Int J Cardiol (2022)
Reported Trait: Plasma triglyceride concentrationβ: 0.122 (0.00495)—% change in TG (per SD PGS): 13.0 [12.0, 14.0]——
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Evaluated Samples

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PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods
Participant Follow-up Time
Sample Numbers
Age of Study Participants
Sample Ancestry
Additional Ancestry Description
Cohort(s)
Additional Sample/Cohort Information
PSS010099——6,952 individuals,
43.5 % Male samples
—European—OBB—
PSS010100——460,037 individuals,
45.7 % Male samples
—European—UKB—
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