Predicted Trait | |
Reported Trait | Marginal zone lymphoma |
Mapped Trait(s) | marginal zone B-cell lymphoma (EFO_1000630) |
Score Construction | |
PGS Name | PRS2_MZL |
Development Method | |
Name | Genome-wide significant SNPs |
Parameters | NR |
Variants | |
Original Genome Build | hg19 |
Number of Variants | 2 |
Effect Weight Type | log(OR) |
PGS Source | |
PGS Catalog Publication (PGP) ID | PGP000448 |
Citation (link to publication) | Berndt SI et al. Leukemia (2022) |
Ancestry Distribution | |
Source of Variant Associations (GWAS) | Not Reported: 100% 4,988 individuals (100%) |
PGS Evaluation | European: 100% 1 Sample Sets |
Study Identifiers | Sample Numbers | Sample Ancestry | Cohort(s) |
---|---|---|---|
GWAS Catalog: GCST001826 Europe PMC: 23349640 |
4,988 individuals | Not reported | NR |
PGS Performance Metric ID (PPM) |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
---|---|---|---|---|---|---|---|---|
PPM017227 | PSS010176| European Ancestry| 20,134 individuals |
PGP000448 | Berndt SI et al. Leukemia (2022) |
Reported Trait: Chronic lymphocytic leukemia | OR: 1.26 [1.09, 1.46] | — | — | — | — |
PPM017235 | PSS010176| European Ancestry| 20,134 individuals |
PGP000448 | Berndt SI et al. Leukemia (2022) |
Reported Trait: Diffuse large B-cell lymphoma | OR: 1.53 [1.34, 1.75] | — | — | — | — |
PPM017243 | PSS010176| European Ancestry| 20,134 individuals |
PGP000448 | Berndt SI et al. Leukemia (2022) |
Reported Trait: Follicular lymphoma | OR: 1.39 [1.21, 1.61] | — | — | — | — |
PPM017251 | PSS010176| European Ancestry| 20,134 individuals |
PGP000448 | Berndt SI et al. Leukemia (2022) |
Reported Trait: Marginal zone lymphoma | OR: 2.43 [1.93, 3.06] | — | — | — | — |
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
---|---|---|---|---|---|---|---|---|
PSS010176 | — | — | [
|
— | European | — | NR | Inter- Lymph Consortium |