Predicted Trait | |
Reported Trait | QRS duration |
Mapped Trait(s) | QRS duration (EFO_0005055) |
Score Construction | |
PGS Name | cont-decay-log_ECG_QRS_duration |
Development Method | |
Name | LDpred2-auto |
Parameters | vec_p_init = seq_log(1e-4, 0.9, length.out = 10), burn_in = 100, num_iter = 500, report_step = 5 |
Variants | |
Original Genome Build | GRCh37 |
Number of Variants | 979,739 |
Effect Weight Type | beta |
PGS Source | |
PGS Catalog Publication (PGP) ID | PGP000457 |
Citation (link to publication) | Ding Y et al. bioRxiv (2022) Preprint |
Study Identifiers | Sample Numbers | Sample Ancestry | Cohort(s) | Phenotype Definitions & Methods | Age of Study Participants | Participant Follow-up Time | Additional Ancestry Description | Additional Sample/Cohort Information |
---|---|---|---|---|---|---|---|---|
— | 28,486 individuals, 0.49 % Male samples |
European | UKB | — | Mean = 55.2 years Sd = 7.4 years |
— | white British | — |
PGS Performance Metric ID (PPM) |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
---|---|---|---|---|---|---|---|---|
PPM017457 | PSS010893| European Ancestry| 1,567 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: QRS duration | — | — | partial-R2: 0.03 | sex, age, deprivation index, PC1-16 | — |
PPM017541 | PSS010809| European Ancestry| 299 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: QRS duration | — | — | partial-R2: 0.03 | sex, age, deprivation index, PC1-16 | — |
PPM017625 | PSS010641| European Ancestry| 400 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: QRS duration | — | — | partial-R2: 0.03 | sex, age, deprivation index, PC1-16 | — |
PPM017709 | PSS010557| Greater Middle Eastern Ancestry| 42 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: QRS duration | — | — | partial-R2: 0.04 | sex, age, deprivation index, PC1-16 | — |
PPM017793 | PSS010221| European Ancestry| 186 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: QRS duration | — | — | partial-R2: 0.02 | sex, age, deprivation index, PC1-16 | — |
PPM017961 | PSS010389| East Asian Ancestry| 115 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: QRS duration | — | — | partial-R2: 0.01 | sex, age, deprivation index, PC1-16 | — |
PPM018129 | PSS010725| African Ancestry| 116 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: QRS duration | — | — | partial-R2: 0.02 | sex, age, deprivation index, PC1-16 | — |
PPM017877 | PSS010473| South Asian Ancestry| 253 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: QRS duration | — | — | partial-R2: 0.04 | sex, age, deprivation index, PC1-16 | — |
PPM018045 | PSS010305| African Ancestry| 67 individuals |
PGP000457 | Ding Y et al. bioRxiv (2022) |Pre |
Reported Trait: QRS duration | — | — | partial-R2: 0.0 | sex, age, deprivation index, PC1-16 | — |
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
---|---|---|---|---|---|---|---|---|
PSS010305 | — | — | 67 individuals, 30.0 % Male samples |
Mean = 49.8 years Sd = 6.5 years |
African American or Afro-Caribbean | Caribbean | UKB | — |
PSS010725 | — | — | 116 individuals, 55.0 % Male samples |
Mean = 49.4 years Sd = 6.7 years |
African unspecified | Nigerian | UKB | — |
PSS010473 | — | — | 253 individuals, 66.0 % Male samples |
Mean = 51.4 years Sd = 7.9 years |
South Asian | Indian | UKB | — |
PSS010221 | — | — | 186 individuals, 55.0 % Male samples |
Mean = 56.5 years Sd = 6.4 years |
European | Ashkenazi | UKB | — |
PSS010893 | — | — | 1,567 individuals, 50.0 % Male samples |
Mean = 55.5 years Sd = 7.4 years |
European | white British | UKB | — |
PSS010641 | — | — | 400 individuals, 47.0 % Male samples |
Mean = 53.6 years Sd = 7.5 years |
European | Italian | UKB | — |
PSS010389 | — | — | 115 individuals, 35.0 % Male samples |
Mean = 51.1 years Sd = 6.9 years |
East Asian | Chinese | UKB | — |
PSS010809 | — | — | 299 individuals, 38.0 % Male samples |
Mean = 52.9 years Sd = 6.6 years |
European | Polish | UKB | — |
PSS010557 | — | — | 42 individuals, 62.0 % Male samples |
Mean = 53.8 years Sd = 6.7 years |
Greater Middle Eastern (Middle Eastern, North African or Persian) | Iranian | UKB | — |