Publications

PGS Publication/Study ID (PGP) PGS Developed PGS Evaluated First Author Title Journal Name Publication Date Digital object identifier (doi) PubMed ID (PMID)
PGP000246 3 3 Chen J The trans-ancestral genomic architecture of glycemic traits. Nat Genet 31/05/2021 10.1038/s41588-021-00852-9 34059833
PGP000181 1 1 Liu G Genome-wide survival study identifies a novel synaptic locus and polygenic score for cognitive progression in Parkinson's disease. Nat Genet 06/05/2021 10.1038/s41588-021-00847-6 33958783
PGP000104 1 1 Koyama S Population-specific and trans-ancestry genome-wide analyses identify distinct and shared genetic risk loci for coronary artery disease. Nat Genet 05/10/2020 10.1038/s41588-020-0705-3 33020668
PGP000088 5 7 Zhang H Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses. Nat Genet 18/05/2020 10.1038/s41588-020-0609-2 32424353
PGP000068 8 8 Cai N Minimal phenotyping yields genome-wide association signals of low specificity for major depression. Nat Genet 30/03/2020 10.1038/s41588-020-0594-5 32231276
PGP000146 1 1 Harper AR Common genetic variants and modifiable risk factors underpin hypertrophic cardiomyopathy susceptibility and expressivity. Nat Genet 25/01/2021 10.1038/s41588-020-00764-0 33495597
PGP000182 1 2 Tadros R Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect. Nat Genet 25/01/2021 10.1038/s41588-020-00762-2 33495596
PGP000128 46 46 Sinnott-Armstrong N Genetics of 35 blood and urine biomarkers in the UK Biobank. Nat Genet 18/01/2021 10.1038/s41588-020-00757-z 33462484
PGP000122 1 1 Conti DV Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction. Nat Genet 04/01/2021 10.1038/s41588-020-00748-0 33398198
PGP000066 1 1 Craig JE Multitrait analysis of glaucoma identifies new risk loci and enables polygenic prediction of disease susceptibility and progression. Nat Genet 20/01/2020 10.1038/s41588-019-0556-y 31959993
PGP000030 1 1 Klarin D Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease. Nat Genet 01/11/2019 10.1038/s41588-019-0519-3 31676865
PGP000063 1 1 Tin A Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels. Nat Genet 02/10/2019 10.1038/s41588-019-0504-x 31578528
PGP000390 1 1 Wuttke M A catalog of genetic loci associated with kidney function from analyses of a million individuals. Nat Genet 31/05/2019 10.1038/s41588-019-0407-x 31152163
PGP000098 1 1 Grove J Identification of common genetic risk variants for autism spectrum disorder. Nat Genet 25/02/2019 10.1038/s41588-019-0344-8 30804558
PGP000086 1 1 Shrine N New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries. Nat Genet 25/02/2019 10.1038/s41588-018-0321-7 30804560
PGP000170 1 0 Huyghe JR Discovery of common and rare genetic risk variants for colorectal cancer. Nat Genet 03/12/2018 10.1038/s41588-018-0286-6 30510241
PGP000023 1 0 Mahajan A Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps. Nat Genet 08/10/2018 10.1038/s41588-018-0241-6 30297969
PGP000283 2 2 Evangelou E Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nat Genet 17/09/2018 10.1038/s41588-018-0205-x 30224653
PGP000006 5 5 Khera AV Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations. Nat Genet 13/08/2018 10.1038/s41588-018-0183-z 30104762
PGP000061 1 1 MacGregor S Genome-wide association study of intraocular pressure uncovers new pathways to glaucoma. Nat Genet 27/07/2018 10.1038/s41588-018-0176-y 30054594
PGP000019 1 1 Schumacher FR Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci. Nat Genet 11/06/2018 10.1038/s41588-018-0142-8 29892016
PGP000410 20 20 Saunders GRB Genetic diversity fuels gene discovery for tobacco and alcohol use. Nature 07/12/2022 10.1038/s41586-022-05477-4 36477530
PGP000382 6 6 Yengo L A saturated map of common genetic variants associated with human height. Nature 12/10/2022 10.1038/s41586-022-05275-y 36224396
PGP000333 2 3 Mishra A Stroke genetics informs drug discovery and risk prediction across ancestries Nature 30/09/2022 10.1038/s41586-022-05165-3 36180795
PGP000458 0 1 Pavelka L Age at onset as stratifier in idiopathic Parkinson's disease - effect of ageing and polygenic risk score on clinical phenotypes. NPJ Parkinsons Dis 09/08/2022 10.1038/s41531-022-00342-7 35945230
PGP000595 65 65 Zhang J An ensemble penalized regression method for multi-ancestry polygenic risk prediction. Nat Commun 15/04/2024 10.1038/s41467-024-47357-7 38622117
PGP000603 2 2 Loginovic P Applying a genetic risk score model to enhance prediction of future multiple sclerosis diagnosis at first presentation with optic neuritis. Nat Commun 28/02/2024 10.1038/s41467-024-44917-9 38418465
PGP000545 2 2 Middha P Polygenic risk score for ulcerative colitis predicts immune checkpoint inhibitor-mediated colitis. Nat Commun 26/03/2024 10.1038/s41467-023-44512-4 38531883
PGP000516 0 1 Soh P X.Y. Prostate cancer genetic risk and associated aggressive disease in men of African ancestry Nature Communications 16/11/2023 10.1038/s41467-023-43726-w 38052806
PGP000501 26 26 Shim I Clinical utility of polygenic scores for cardiometabolic disease in Arabs. Nature Communications 18/10/2023 10.1038/s41467-023-41985-1 37852978
PGP000511 1 1 Rasooly D Genome-wide association analysis and Mendelian randomization proteomics identify drug targets for heart failure. Nat Commun 10/07/2023 10.1038/s41467-023-39253-3 37429843
PGP000510 8 2 Kurniansyah N Evaluating the use of blood pressure polygenic risk scores across race/ethnic background groups. Nat Commun 02/06/2023 10.1038/s41467-023-38990-9 37268629
PGP000434 1 1 Khurshid S Clinical and genetic associations of deep learning-derived cardiac magnetic resonance-based left ventricular mass. Nat Commun 21/03/2023 10.1038/s41467-023-37173-w 36944631
PGP000429 2 2 Seviiri M A multi-phenotype analysis reveals 19 susceptibility loci for basal cell carcinoma and 15 for squamous cell carcinoma. Nat Commun 10/12/2022 10.1038/s41467-022-35345-8 36496446
PGP000426 1 1 Gao XR Whole-exome sequencing study identifies rare variants and genes associated with intraocular pressure and glaucoma. Nat Commun 30/11/2022 10.1038/s41467-022-35188-3 36450729
PGP000427 1 1 Krohn L Genome-wide association study of REM sleep behavior disorder identifies polygenic risk and brain expression effects. Nat Commun 05/12/2022 10.1038/s41467-022-34732-5 36470867
PGP000405 18 18 Kim YJ The contribution of common and rare genetic variants to variation in metabolic traits in 288,137 East Asians. Nat Commun 04/11/2022 10.1038/s41467-022-34163-2 36333282
PGP000314 1 1 Pujol-Gualdo N Advancing our understanding of genetic risk factors and potential personalized strategies for pelvic organ prolapse. Nat Commun 23/06/2022 10.1038/s41467-022-31188-5 35739095
PGP000531 4 4 Kurniansyah N A multi-ethnic polygenic risk score is associated with hypertension prevalence and progression throughout adulthood. Nat Commun 21/06/2022 10.1038/s41467-022-31080-2 35729114
PGP000391 3 3 Agrawal S Inherited basis of visceral, abdominal subcutaneous and gluteofemoral fat depots. Nat Commun 30/06/2022 10.1038/s41467-022-30931-2 35773277
PGP000320 1 1 He YQ A polygenic risk score for nasopharyngeal carcinoma shows potential for risk stratification and personalized screening. Nat Commun 12/04/2022 10.1038/s41467-022-29570-4 35414057
PGP000164 3 3 Khan Z Genetic variation associated with thyroid autoimmunity shapes the systemic immune response to PD-1 checkpoint blockade. Nat Commun 07/06/2021 10.1038/s41467-021-23661-4 34099659
PGP000231 1 1 de Rojas I Common variants in Alzheimer's disease and risk stratification by polygenic risk scores. Nat Commun 07/06/2021 10.1038/s41467-021-22491-8 34099642
PGP000201 3 3 Pazoki R Genetic analysis in European ancestry individuals identifies 517 loci associated with liver enzymes. Nat Commun 10/05/2021 10.1038/s41467-021-22338-2 33972514
PGP000147 0 11 Thareja G Whole genome sequencing in the Middle Eastern Qatari population identifies genetic associations with 45 clinically relevant traits. Nat Commun 23/02/2021 10.1038/s41467-021-21381-3 33623009
PGP000050 16 16 Graff RE Cross-cancer evaluation of polygenic risk scores for 16 cancer types in two large cohorts. Nat Commun 12/02/2021 10.1038/s41467-021-21288-z 33579919
PGP000149 1 1 Huynh-Le MP Polygenic hazard score is associated with prostate cancer in multi-ethnic populations. Nat Commun 23/02/2021 10.1038/s41467-021-21287-0 33623038
PGP000160 1 1 Wang YF Identification of 38 novel loci for systemic lupus erythematosus and genetic heterogeneity between ancestral groups. Nat Commun 03/02/2021 10.1038/s41467-021-21049-y 33536424
PGP000138 3 3 Fontanillas P Disease risk scores for skin cancers. Nat Commun 08/01/2021 10.1038/s41467-020-20246-5 33420020
PGP000102 1 3 Mars N The role of polygenic risk and susceptibility genes in breast cancer over the course of life Nat Commun 14/12/2020 10.1038/s41467-020-19966-5 33318493
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