Trait: anxiety disorder

Experimental Factor Ontology (EFO) Information
Identifier EFO_0006788
Description A category of psychiatric disorders which are characterized by anxious feelings or fear often accompanied by physical symptoms associated with anxiety. [NCIT: C2878]
Trait category
Neurological disorder
Synonyms 11 synonyms
  • anxiety
  • anxiety disorder
  • anxiety disorders
  • anxiety neuroses
  • anxiety neurosis
  • anxiety state
  • anxiety/mood disorders
  • chronic stress
  • mood and anxiety disorder
  • mood and anxiety disorders
  • neurotic anxiety states
Mapped terms 13 mapped terms
  • DOID:2030
  • ICD10:F41
  • ICD9:300.09
  • MESH:D001008
  • MONDO:0005618
  • MeSH:D001008
  • MedDRA:10057666
  • NCIT:C2878
  • NCIt:C2878
  • SCTID:197480006
  • SNOMEDCT:197480006
  • UMLS:C0003469
  • Wikipedia:Anxiety_disorder

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS004451
(disease.F41.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 F41 (Other anxiety disorders) anxiety disorder 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004451/ScoringFiles/PGS004451.txt.gz
PGS004521
(meta.F41.score)
 PGP000561 |
Jung H et al. Commun Biol (2024)
 F41 (Other anxiety disorders) anxiety disorder 1,059,939
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004521/ScoringFiles/PGS004521.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM020566 PGS004451
(disease.F41.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: F41 (Other anxiety disorders) OR: 1.18672 — — — —
PPM020636 PGS004521
(meta.F41.score)
 PSS011364|
European Ancestry|
56,192 individuals
 PGP000561 |
Jung H et al. Commun Biol (2024)
 Reported Trait: F41 (Other anxiety disorders) OR: 1.29571 — — — —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS011364 — — 56,192 individuals — European — UKB —