PGS Publication: PGP000431

Publication Information (EuropePMC)
Title Genome-wide association study reveals ethnicity-specific SNPs associated with ankylosing spondylitis in the Taiwanese population.
PubMed ID 36510243(Europe PMC)
doi 10.1186/s12967-022-03701-3
Publication Date Dec. 12, 2022
Journal J Transl Med
Author(s) Ko CL, Lin WZ, Lee MT, Chang YT, Lin HC, Wu YS, Lin JF, Pan KT, Chang YC, Lee KH, Lee YL, Hsieh TT, ... Huang JH, Wang CH, Yang SS, Chen HC, Chu CM.Show more
Released in PGS Catalog: Feb. 8, 2023

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported

PGS Developed By This Publication

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Polygenic Score ID & Name
PGS Publication ID (PGP)
Reported Trait
Mapped Trait(s) (Ontology)
Number of Variants
Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS003420
(PRS100_PRScs)
PGP000431 |
Ko CL et al. J Transl Med (2022)
Ankylosing spondylitisankylosing spondylitis100
G
-
E
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003420/ScoringFiles/PGS003420.txt.gz
PGS003421
(PRS16_C+T)
PGP000431 |
Ko CL et al. J Transl Med (2022)
Ankylosing spondylitisankylosing spondylitis16
G
-
E
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003421/ScoringFiles/PGS003421.txt.gz
PGS003422
(PRS16_PRSice2)
PGP000431 |
Ko CL et al. J Transl Med (2022)
Ankylosing spondylitisankylosing spondylitis16
G
-
E
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003422/ScoringFiles/PGS003422.txt.gz
PGS003423
(PRS100_Lassosum)
PGP000431 |
Ko CL et al. J Transl Med (2022)
Ankylosing spondylitisankylosing spondylitis100
G
-
E
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003423/ScoringFiles/PGS003423.txt.gz
PGS003424
(PRS100_LDpred2)
PGP000431 |
Ko CL et al. J Transl Med (2022)
Ankylosing spondylitisankylosing spondylitis100
G
-
E
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003424/ScoringFiles/PGS003424.txt.gz
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Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

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PGS Performance
Metric ID (PPM)
Evaluated Score
PGS Sample Set ID
(PSS)
Performance Source
Trait
PGS Effect Sizes
(per SD change)
Classification Metrics
Other Metrics
Covariates Included in the Model
PGS Performance:
Other Relevant Information
PPM017073PGS003420
(PRS100_PRScs)
PSS010115|
East Asian Ancestry|
1,298 individuals
PGP000431 |
Ko CL et al. J Transl Med (2022)
Reported Trait: Ankylosing spondylitis—AUROC: 0.7886———
PPM017074PGS003421
(PRS16_C+T)
PSS010115|
East Asian Ancestry|
1,298 individuals
PGP000431 |
Ko CL et al. J Transl Med (2022)
Reported Trait: Ankylosing spondylitis—AUROC: 0.7876———
PPM017075PGS003422
(PRS16_PRSice2)
PSS010115|
East Asian Ancestry|
1,298 individuals
PGP000431 |
Ko CL et al. J Transl Med (2022)
Reported Trait: Ankylosing spondylitis—AUROC: 0.7876———
PPM017076PGS003423
(PRS100_Lassosum)
PSS010115|
East Asian Ancestry|
1,298 individuals
PGP000431 |
Ko CL et al. J Transl Med (2022)
Reported Trait: Ankylosing spondylitis—AUROC: 0.7754———
PPM017077PGS003424
(PRS100_LDpred2)
PSS010115|
East Asian Ancestry|
1,298 individuals
PGP000431 |
Ko CL et al. J Transl Med (2022)
Reported Trait: Ankylosing spondylitis—AUROC: 0.7605———
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Evaluated Samples

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PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods
Participant Follow-up Time
Sample Numbers
Age of Study Participants
Sample Ancestry
Additional Ancestry Description
Cohort(s)
Additional Sample/Cohort Information
PSS010115——
[
  • 185 cases
  • , 1,112 controls
]
—East Asian
(Taiwanese)		—NRTPMI
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