PGS Publication: PGP000521

Publication Information (EuropePMC)
Title Genetic predisposition to macronutrient preference and workplace food choices.
PubMed ID 37217678(Europe PMC)
doi 10.1038/s41380-023-02107-x
Publication Date May 23, 2023
Journal Mol Psychiatry
Author(s) Merino J, Dashti HS, Levy DE, Del Rocío Sevilla-González M, Hivert MF, Porneala BC, Saxena R, Thorndike AN.
Released in PGS Catalog: Dec. 15, 2023

Associated Polygenic Score(s)

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Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
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Additional Diverse Ancestries
Not Reported

PGS Developed By This Publication

Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS004221
(PRS8_carbohydrate)
 PGP000521 |
Merino J et al. Mol Psychiatry (2023)
 Carbohydrate preference carbohydrate intake measurement 8
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004221/ScoringFiles/PGS004221.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM020156 PGS004221
(PRS8_carbohydrate)
 PSS011297|
European Ancestry|
397 individuals
 PGP000521 |
Merino J et al. Mol Psychiatry (2023)
 Reported Trait: Number of 'green' beverages purchased per month β: 1.1 [0.3, 1.9] — — age, sex, education level (high school/some college, college degree, graduate degree), job type (administrative/service, craft/technicians, management/professionals, MDs/PhDs), BMI (18.5-24.9 kg/m2, 25.0-29.9 kg/m2, and ≥30 kg/m2), current smoking status (yes, no), and physical activity (categorized into low, intermediate, and high physical activity level) —
PPM020154 PGS004221
(PRS8_carbohydrate)
 PSS011297|
European Ancestry|
397 individuals
 PGP000521 |
Merino J et al. Mol Psychiatry (2023)
 Reported Trait: Total workplace purchases per month β: 2.3 [0.2, 4.3] — — age, sex, education level (high school/some college, college degree, graduate degree), job type (administrative/service, craft/technicians, management/professionals, MDs/PhDs), BMI (18.5-24.9 kg/m2, 25.0-29.9 kg/m2, and ≥30 kg/m2), current smoking status (yes, no), and physical activity (categorized into low, intermediate, and high physical activity level) —
PPM020155 PGS004221
(PRS8_carbohydrate)
 PSS011297|
European Ancestry|
397 individuals
 PGP000521 |
Merino J et al. Mol Psychiatry (2023)
 Reported Trait: Number of 'green' items purchased per month β: 1.9 [0.5, 3.3] — — age, sex, education level (high school/some college, college degree, graduate degree), job type (administrative/service, craft/technicians, management/professionals, MDs/PhDs), BMI (18.5-24.9 kg/m2, 25.0-29.9 kg/m2, and ≥30 kg/m2), current smoking status (yes, no), and physical activity (categorized into low, intermediate, and high physical activity level) —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS011297 — — 397 individuals,
19.1 % Male samples
 — European — ChooseWell 365 —