PGS Publication: PGP000540

Publication Information (EuropePMC)
Title Ultra-processed food consumption, genetic predisposition, and the risk of gout: the UK Biobank study.
PubMed ID 37129545(Europe PMC)
doi 10.1093/rheumatology/kead196
Publication Date May 2, 2023
Journal Rheumatology (Oxford)
Author(s) Zhang T, Xu X, Chang Q, Lv Y, Zhao Y, Niu K, Chen L, Xia Y.
Released in PGS Catalog: Dec. 15, 2023

Associated Polygenic Score(s)

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Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
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Not Reported

External PGS Evaluated By This Publication

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Polygenic Score ID & Name
PGS Publication ID (PGP)
Reported Trait
Mapped Trait(s) (Ontology)
Number of Variants
Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS002307
(PRS33_gout)
PGP000329 |
Zhang Y et al. BMC Med (2022)
Goutgout33
G
-
E
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002307/ScoringFiles/PGS002307.txt.gz
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Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

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PGS Performance
Metric ID (PPM)
Evaluated Score
PGS Sample Set ID
(PSS)
Performance Source
Trait
PGS Effect Sizes
(per SD change)
Classification Metrics
Other Metrics
Covariates Included in the Model
PGS Performance:
Other Relevant Information
PPM020291PGS002307
(PRS33_gout)
PSS011325|
European Ancestry|
181,559 individuals
PGP000540 |
Zhang T et al. Rheumatology (Oxford) (2023)
|Ext.		Reported Trait: Incident gout with ultraprocessed food consumption——Hazard ratio (HR, high UPF consumption and highest PRS quartile vs. low UPF consumption and lowest PRS quartile): 1.9 [1.39, 2.6]age, sex, BMI, education levels, Townsend deprivation index, physical activity, smoking status, drin... king status, family history of diseases (hypertension, cardiovascular disease, and diabetes), healthy diet score, ultra-processed food consumption, medical history of hypertension, diabetes, kidney disease, cancer, and cardiovascular disease, first ten genetic principal components and genotype measurement batchShow more—
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Evaluated Samples

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PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods
Participant Follow-up Time
Sample Numbers
Age of Study Participants
Sample Ancestry
Additional Ancestry Description
Cohort(s)
Additional Sample/Cohort Information
PSS011325——181,559 individuals—European—UKB—
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