Polygenic Score (PGS) ID: PGS000116

Predicted Trait
Reported Trait Coronary artery disease
Mapped Trait(s) coronary artery disease (EFO_0001645)
Released in PGS Catalog: March 27, 2020
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Terms and Licenses
CC0 1.0 Universal (CC0 1.0) Public Domain Dedication

Score Details

Score Construction
PGS Name CAD_EJ2020
Development Method
Name lassosum
Parameters INFO score>0.999; N=1,037,385 variants; s=0.5; lambda=0.00428
Variants
Original Genome Build GRCh37
Number of Variants 40,079
Effect Weight Type NR
PGS Source
PGS Catalog Publication (PGP) ID PGP000054
Citation (link to publication) Elliott J et al. JAMA (2020)
Ancestry Distribution
Source of Variant
Associations (GWAS)
European: 75.3%
South Asian: 13.6%
East Asian: 6%
Hispanic or Latin American: 2.2%
African: 1.7%
Greater Middle Eastern: 1.2%
187,599 individuals (100%)
Score Development/Training
Multi-ancestry (including European): 100%
  • European
  • East Asian
  • South Asian
  • Additional Asian Ancestries
  • Not Reported
80,103 individuals (100%)
PGS Evaluation
Multi-ancestry (including European): 83.3%
  • European
  • South Asian
  • African
  • East Asian
  • Additional Asian Ancestries
  • Not Reported
European: 16.7%
12 Sample Sets

Development Samples

Source of Variant Associations (GWAS)
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Study Identifiers
Sample Numbers
Sample Ancestry
Cohort(s)
GWAS Catalog: GCST003116
Europe PMC: 26343387
2,268 individualsGreater Middle Eastern (Middle Eastern, North African or Persian)40 cohorts
  • ADVANCE
  • ,AGES
  • ,AIDHS
  • ,ARIC
  • ,BAS
  • ,BioMe
  • ,CARDIOGENICS
  • ,CAS
  • ,CCGB
  • ,COROGENE
  • ,DUKE_2
  • ,EGCUT
  • ,FGENTCARD
  • ,FHS
  • ,FINRISK
  • ,FamHS
  • ,GENRIC
  • ,GerMIFS
  • ,GoDARTS
  • ,HPS
  • ,HSDS
  • ,HSIEA
  • ,ITH
  • ,LIFE-HEART
  • ,LOLIPOP
  • ,LURIC
  • ,MAYO-VDB
  • ,MIGen
  • ,MedSTAR
  • ,OHGS
  • ,PIVUS
  • ,PROCARDIS
  • ,PROMIS
  • ,PROSPER
  • ,PennCATH
  • ,RS
  • ,TwinGene
  • ,ULSAM
  • ,WGHS
  • ,WTCCC
GWAS Catalog: GCST003116
Europe PMC: 26343387
3,139 individualsAfrican American or Afro-Caribbean41 cohorts
  • ADVANCE
  • ,AGES
  • ,AIDHS
  • ,ARIC
  • ,BAS
  • ,BioMe
  • ,CARDIOGENICS
  • ,CAS
  • ,CCGB
  • ,COROGENE
  • ,DUKE_2
  • ,EGCUT
  • ,FGENTCARD
  • ,FHS
  • ,FINRISK
  • ,FamHS
  • ,GENRIC
  • ,GerMIFS
  • ,GoDARTS
  • ,HPS
  • ,HSDS
  • ,HSIEA
  • ,ITH
  • ,LIFE-HEART
  • ,LOLIPOP
  • ,LURIC
  • ,MAYO-VDB
  • ,MIGen
  • ,MedSTAR
  • ,OHGS
  • ,PIVUS
  • ,PROCARDIS
  • ,PROMIS
  • ,PROSPER
  • ,PennCATH
  • ,RS
  • ,SDS
  • ,TwinGene
  • ,ULSAM
  • ,WGHS
  • ,WTCCC
GWAS Catalog: GCST003116
Europe PMC: 26343387
4,095 individualsHispanic or Latin American41 cohorts
  • ADVANCE
  • ,AGES
  • ,AIDHS
  • ,ARIC
  • ,BAS
  • ,BioMe
  • ,CARDIOGENICS
  • ,CAS
  • ,CCGB
  • ,COROGENE
  • ,DUKE_2
  • ,EGCUT
  • ,FGENTCARD
  • ,FHS
  • ,FINRISK
  • ,FamHS
  • ,GENRIC
  • ,GerMIFS
  • ,GoDARTS
  • ,HPS
  • ,HSDS
  • ,HSIEA
  • ,ITH
  • ,LIFE-HEART
  • ,LOLIPOP
  • ,LURIC
  • ,MAYO-VDB
  • ,MIGen
  • ,MedSTAR
  • ,OHGS
  • ,PIVUS
  • ,PROCARDIS
  • ,PROMIS
  • ,PROSPER
  • ,PennCATH
  • ,RS
  • ,SDS
  • ,TwinGene
  • ,ULSAM
  • ,WGHS
  • ,WTCCC
GWAS Catalog: GCST003116
Europe PMC: 26343387
11,323 individualsEast Asian41 cohorts
  • ADVANCE
  • ,AGES
  • ,AIDHS
  • ,ARIC
  • ,BAS
  • ,BioMe
  • ,CARDIOGENICS
  • ,CAS
  • ,CCGB
  • ,COROGENE
  • ,DUKE_2
  • ,EGCUT
  • ,FGENTCARD
  • ,FHS
  • ,FINRISK
  • ,FamHS
  • ,GENRIC
  • ,GerMIFS
  • ,GoDARTS
  • ,HPS
  • ,HSDS
  • ,HSIEA
  • ,ITH
  • ,LIFE-HEART
  • ,LOLIPOP
  • ,LURIC
  • ,MAYO-VDB
  • ,MIGen
  • ,MedSTAR
  • ,OHGS
  • ,PIVUS
  • ,PROCARDIS
  • ,PROMIS
  • ,PROSPER
  • ,PennCATH
  • ,RS
  • ,SDS
  • ,TwinGene
  • ,ULSAM
  • ,WGHS
  • ,WTCCC
GWAS Catalog: GCST003116
Europe PMC: 26343387
25,557 individualsSouth Asian41 cohorts
  • ADVANCE
  • ,AGES
  • ,AIDHS
  • ,ARIC
  • ,BAS
  • ,BioMe
  • ,CARDIOGENICS
  • ,CAS
  • ,CCGB
  • ,COROGENE
  • ,DUKE_2
  • ,EGCUT
  • ,FGENTCARD
  • ,FHS
  • ,FINRISK
  • ,FamHS
  • ,GENRIC
  • ,GerMIFS
  • ,GoDARTS
  • ,HPS
  • ,HSDS
  • ,HSIEA
  • ,ITH
  • ,LIFE-HEART
  • ,LOLIPOP
  • ,LURIC
  • ,MAYO-VDB
  • ,MIGen
  • ,MedSTAR
  • ,OHGS
  • ,PIVUS
  • ,PROCARDIS
  • ,PROMIS
  • ,PROSPER
  • ,PennCATH
  • ,RS
  • ,SDS
  • ,TwinGene
  • ,ULSAM
  • ,WGHS
  • ,WTCCC
GWAS Catalog: GCST003116
Europe PMC: 26343387
141,217 individualsEuropean41 cohorts
  • ADVANCE
  • ,AGES
  • ,AIDHS
  • ,ARIC
  • ,BAS
  • ,BioMe
  • ,CARDIOGENICS
  • ,CAS
  • ,CCGB
  • ,COROGENE
  • ,DUKE_2
  • ,EGCUT
  • ,FGENTCARD
  • ,FHS
  • ,FINRISK
  • ,FamHS
  • ,GENRIC
  • ,GerMIFS
  • ,GoDARTS
  • ,HPS
  • ,HSDS
  • ,HSIEA
  • ,ITH
  • ,LIFE-HEART
  • ,LOLIPOP
  • ,LURIC
  • ,MAYO-VDB
  • ,MIGen
  • ,MedSTAR
  • ,OHGS
  • ,PIVUS
  • ,PROCARDIS
  • ,PROMIS
  • ,PROSPER
  • ,PennCATH
  • ,RS
  • ,SDS
  • ,TwinGene
  • ,ULSAM
  • ,WGHS
  • ,WTCCC
Showing 1 to 6 of 6 rows
Score Development/Training
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Study Identifiers
Sample Numbers
Sample Ancestry
Cohort(s)
Phenotype Definitions & Methods
Age of Study Participants
Participant Follow-up Time
Additional Ancestry Description
Additional Sample/Cohort Information
—
[
  • 15,947 cases
  • , 64,156 controls
]
,
68.24 % Male samples
European, East Asian, South Asian, Asian unspecified, NRUKBCoronary artery disease was defined as myocardial infarction and its related sequelae (coronary angi... oplasty, and coronary artery bypass grafts). ICD-10 codes: I21, I22, I23, I24.1, I25.2 ICD-9 codes: 410, 411, 412, 429.79 OPCS-4 codes: K40.1-4, K41.1-4, K45.1-5, K49.1-2, K49.8-9, K50.2, K75.1-4, K54.8-9 UKBiobank field 20002 code: 1075 UKBiobank field 20004 codes: 1070, 1095 UKBiobank field 6150 code: 1 See eTable 1 for risk factor codingsShow moreMean = 60.0 years—95% European, 0.2% Chinese, 1,4% Indian,0.4%Other Asian, 0.5% Pakistani, 1.1 % Other ancestriesTuning (Case-Control) Set
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Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

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PGS Performance
Metric ID (PPM)
PGS Sample Set ID
(PSS)
Performance Source
Trait
PGS Effect Sizes
(per SD change)
Classification Metrics
Other Metrics
Covariates Included in the Model
PGS Performance:
Other Relevant Information
PPM000806PSS000399|
Multi-ancestry (including European)|
352,660 individuals
PGP000054 |
Elliott J et al. JAMA (2020)
Reported Trait: Incident coronary artery diseaseHR: 1.32 [1.3, 1.34]C-index: 0.61 [0.6, 0.62]———
PPM000807PSS000399|
Multi-ancestry (including European)|
352,660 individuals
PGP000054 |
Elliott J et al. JAMA (2020)
Reported Trait: Incident coronary artery disease—C-index: 0.76 [0.75, 0.76]—age,sex—
PPM000808PSS000399|
Multi-ancestry (including European)|
352,660 individuals
PGP000054 |
Elliott J et al. JAMA (2020)
Reported Trait: Incident coronary artery disease—C-index: 0.78 [0.77, 0.79]—pooled cohort equations—
PPM000809PSS000387|
Multi-ancestry (including European)|
204,675 individuals
PGP000054 |
Elliott J et al. JAMA (2020)
Reported Trait: Incident coronary artery disease (over age 55)—C-index: 0.6 [0.59, 0.61]———
PPM000810PSS000387|
Multi-ancestry (including European)|
204,675 individuals
PGP000054 |
Elliott J et al. JAMA (2020)
Reported Trait: Incident coronary artery disease (over age 55)—C-index: 0.71 [0.7, 0.72]—age,sex—
PPM000811PSS000387|
Multi-ancestry (including European)|
204,675 individuals
PGP000054 |
Elliott J et al. JAMA (2020)
Reported Trait: Incident coronary artery disease (over age 55)—C-index: 0.74 [0.73, 0.74]—pooled cohort equations—
PPM000812PSS000383|
Multi-ancestry (including European)|
147,985 individuals
PGP000054 |
Elliott J et al. JAMA (2020)
Reported Trait: Incident coronary artery disease (under age 55)—C-index: 0.64 [0.63, 0.66]———
PPM000813PSS000383|
Multi-ancestry (including European)|
147,985 individuals
PGP000054 |
Elliott J et al. JAMA (2020)
Reported Trait: Incident coronary artery disease (under age 55)—C-index: 0.76 [0.75, 0.78]—age,sex—
PPM000814PSS000383|
Multi-ancestry (including European)|
147,985 individuals
PGP000054 |
Elliott J et al. JAMA (2020)
Reported Trait: Incident coronary artery disease (under age 55)—C-index: 0.8 [0.79, 0.82]—pooled cohort equations—
PPM000815PSS000391|
Multi-ancestry (including European)|
147,363 individuals
PGP000054 |
Elliott J et al. JAMA (2020)
Reported Trait: Incident coronary artery disease (in males)—C-index: 0.61 [0.6, 0.62]———
PPM000816PSS000391|
Multi-ancestry (including European)|
147,363 individuals
PGP000054 |
Elliott J et al. JAMA (2020)
Reported Trait: Incident coronary artery disease (in males)—C-index: 0.68 [0.67, 0.69]—age,sex—
PPM000817PSS000391|
Multi-ancestry (including European)|
147,363 individuals
PGP000054 |
Elliott J et al. JAMA (2020)
Reported Trait: Incident coronary artery disease (in males)—C-index: 0.71 [0.7, 0.72]—pooled cohort equations—
PPM000818PSS000395|
Multi-ancestry (including European)|
205,297 individuals
PGP000054 |
Elliott J et al. JAMA (2020)
Reported Trait: Incident coronary artery disease (in females)—C-index: 0.61 [0.6, 0.63]———
PPM000819PSS000395|
Multi-ancestry (including European)|
205,297 individuals
PGP000054 |
Elliott J et al. JAMA (2020)
Reported Trait: Incident coronary artery disease (in females)—C-index: 0.71 [0.7, 0.73]—age,sex—
PPM000820PSS000395|
Multi-ancestry (including European)|
205,297 individuals
PGP000054 |
Elliott J et al. JAMA (2020)
Reported Trait: Incident coronary artery disease (in females)—C-index: 0.76 [0.74, 0.77]—pooled cohort equations—
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Evaluated Samples

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PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods
Participant Follow-up Time
Sample Numbers
Age of Study Participants
Sample Ancestry
Additional Ancestry Description
Cohort(s)
Additional Sample/Cohort Information
PSS000383Coronary artery disease was defined as myocardial infarction and its related sequelae (coronary angi... oplasty, and coronary artery bypass grafts). ICD-10 codes: I21, I22, I23, I24.1, I25.2 ICD-9 codes: 410, 411, 412, 429.79 OPCS-4 codes: K40.1-4, K41.1-4, K45.1-5, K49.1-2, K49.8-9, K50.2, K75.1-4, K54.8-9 UKBiobank field 20002 code: 1075 UKBiobank field 20004 codes: 1070, 1095 UKBiobank field 6150 code: 1 See eTable 1 for risk factor codingsShow moreMean = 8.01 years
Sd = 1.04 years
[
  • 1,350 cases
  • , 146,635 controls
]
Range = [40.0, 55.0] yearsEuropean, African unspecified, NR98.3% White European, 1.7% Black/OtherUKBPCE Prospective Cohort (lipid-lowering treatment performed)
PSS000385Coronary artery disease was defined as myocardial infarction and its related sequelae (coronary angi... oplasty, and coronary artery bypass grafts). ICD-10 codes: I21, I22, I23, I24.1, I25.2 ICD-9 codes: 410, 411, 412, 429.79 OPCS-4 codes: K40.1-4, K41.1-4, K45.1-5, K49.1-2, K49.8-9, K50.2, K75.1-4, K54.8-9 UKBiobank field 20002 code: 1075 UKBiobank field 20004 codes: 1070, 1095 UKBiobank field 6150 code: 1 See eTable 1 for risk factor codingsShow moreMean = 8.01 years
Sd = 1.04 years
[
  • 1,339 cases
  • , 145,771 controls
]
Range = [40.0, 55.0] yearsEuropean, South Asian, African American or Afro-Caribbean, African unspecified, East Asian, Asian unspecified2,332 Africans, 145 Bangladeshi, 3,165 Carribeans, 1,136 Chinese, 3,790 Indians, 1,258 Other Asians, 1,182 Pakistani, 332,326 White Europeans and Unkown ancestryUKBQRISK3 Prospective Cohort/Testing Set (lipid-lowering treatment performed)
PSS000387Coronary artery disease was defined as myocardial infarction and its related sequelae (coronary angi... oplasty, and coronary artery bypass grafts). ICD-10 codes: I21, I22, I23, I24.1, I25.2 ICD-9 codes: 410, 411, 412, 429.79 OPCS-4 codes: K40.1-4, K41.1-4, K45.1-5, K49.1-2, K49.8-9, K50.2, K75.1-4, K54.8-9 UKBiobank field 20002 code: 1075 UKBiobank field 20004 codes: 1070, 1095 UKBiobank field 6150 code: 1 See eTable 1 for risk factor codingsShow moreMean = 8.01 years
Sd = 1.04 years
[
  • 4,922 cases
  • , 199,753 controls
]
Range = [55.0, 69.0] yearsEuropean, African unspecified, NR98.3% White European, 1.7% Black/OtherUKBPCE Prospective Cohort (lipid-lowering treatment performed)
PSS000389Coronary artery disease was defined as myocardial infarction and its related sequelae (coronary angi... oplasty, and coronary artery bypass grafts). ICD-10 codes: I21, I22, I23, I24.1, I25.2 ICD-9 codes: 410, 411, 412, 429.79 OPCS-4 codes: K40.1-4, K41.1-4, K45.1-5, K49.1-2, K49.8-9, K50.2, K75.1-4, K54.8-9 UKBiobank field 20002 code: 1075 UKBiobank field 20004 codes: 1070, 1095 UKBiobank field 6150 code: 1 See eTable 1 for risk factor codingsShow moreMean = 8.01 years
Sd = 1.04 years
[
  • 4,900 cases
  • , 198,720 controls
]
Range = [55.0, 69.0] yearsEuropean, South Asian, African American or Afro-Caribbean, African unspecified, East Asian, Asian unspecified2,332 Africans, 145 Bangladeshi, 3,165 Carribeans, 1,136 Chinese, 3,790 Indians, 1,258 Other Asians, 1,182 Pakistani, 332,326 White Europeans and Unkown ancestryUKBQRISK3 Prospective Cohort/Testing Set (lipid-lowering treatment performed)
PSS000391Coronary artery disease was defined as myocardial infarction and its related sequelae (coronary angi... oplasty, and coronary artery bypass grafts). ICD-10 codes: I21, I22, I23, I24.1, I25.2 ICD-9 codes: 410, 411, 412, 429.79 OPCS-4 codes: K40.1-4, K41.1-4, K45.1-5, K49.1-2, K49.8-9, K50.2, K75.1-4, K54.8-9 UKBiobank field 20002 code: 1075 UKBiobank field 20004 codes: 1070, 1095 UKBiobank field 6150 code: 1 See eTable 1 for risk factor codingsShow moreMean = 8.01 years
Sd = 1.04 years
[
  • 4,493 cases
  • , 142,870 controls
]
,
100.0 % Male samples
Mean = 55.79 years
Sd = 8.35 years		European, African unspecified, NR98.3% White European, 1.7% Black/OtherUKBPCE Prospective Cohort (lipid-lowering treatment performed)
PSS000393Coronary artery disease was defined as myocardial infarction and its related sequelae (coronary angi... oplasty, and coronary artery bypass grafts). ICD-10 codes: I21, I22, I23, I24.1, I25.2 ICD-9 codes: 410, 411, 412, 429.79 OPCS-4 codes: K40.1-4, K41.1-4, K45.1-5, K49.1-2, K49.8-9, K50.2, K75.1-4, K54.8-9 UKBiobank field 20002 code: 1075 UKBiobank field 20004 codes: 1070, 1095 UKBiobank field 6150 code: 1 See eTable 1 for risk factor codingsShow moreMean = 8.01 years
Sd = 1.04 years
[
  • 4,471 cases
  • , 142,102 controls
]
,
100.0 % Male samples
Mean = 55.8 years
Sd = 8.3 years		European, South Asian, African American or Afro-Caribbean, African unspecified, East Asian, Asian unspecified2,332 Africans, 145 Bangladeshi, 3,165 Carribeans, 1,136 Chinese, 3,790 Indians, 1,258 Other Asians, 1,182 Pakistani, 332,326 White Europeans and Unkown ancestryUKBQRISK3 Prospective Cohort/Testing Set (lipid-lowering treatment performed)
PSS000395Coronary artery disease was defined as myocardial infarction and its related sequelae (coronary angi... oplasty, and coronary artery bypass grafts). ICD-10 codes: I21, I22, I23, I24.1, I25.2 ICD-9 codes: 410, 411, 412, 429.79 OPCS-4 codes: K40.1-4, K41.1-4, K45.1-5, K49.1-2, K49.8-9, K50.2, K75.1-4, K54.8-9 UKBiobank field 20002 code: 1075 UKBiobank field 20004 codes: 1070, 1095 UKBiobank field 6150 code: 1 See eTable 1 for risk factor codingsShow moreMean = 8.01 years
Sd = 1.04 years
[
  • 1,779 cases
  • , 203,518 controls
]
,
0.0 % Male samples
Mean = 56.0 years
Sd = 8.01 years		European, African unspecified, NR98.3% White European, 1.7% Black/OtherUKBPCE Prospective Cohort (lipid-lowering treatment performed)
PSS000397Coronary artery disease was defined as myocardial infarction and its related sequelae (coronary angi... oplasty, and coronary artery bypass grafts). ICD-10 codes: I21, I22, I23, I24.1, I25.2 ICD-9 codes: 410, 411, 412, 429.79 OPCS-4 codes: K40.1-4, K41.1-4, K45.1-5, K49.1-2, K49.8-9, K50.2, K75.1-4, K54.8-9 UKBiobank field 20002 code: 1075 UKBiobank field 20004 codes: 1070, 1095 UKBiobank field 6150 code: 1 See eTable 1 for risk factor codingsShow moreMean = 8.01 years
Sd = 1.04 years
[
  • 1,768 cases
  • , 202,389 controls
]
,
0.0 % Male samples
Mean = 56.0 years
Sd = 8.0 years		European, South Asian, African American or Afro-Caribbean, African unspecified, East Asian, Asian unspecified2,332 Africans, 145 Bangladeshi, 3,165 Carribeans, 1,136 Chinese, 3,790 Indians, 1,258 Other Asians, 1,182 Pakistani, 332,326 White Europeans and Unkown ancestryUKBQRISK3 Prospective Cohort/Testing Set (lipid-lowering treatment performed)
PSS000399Coronary artery disease was defined as myocardial infarction and its related sequelae (coronary angi... oplasty, and coronary artery bypass grafts). ICD-10 codes: I21, I22, I23, I24.1, I25.2 ICD-9 codes: 410, 411, 412, 429.79 OPCS-4 codes: K40.1-4, K41.1-4, K45.1-5, K49.1-2, K49.8-9, K50.2, K75.1-4, K54.8-9 UKBiobank field 20002 code: 1075 UKBiobank field 20004 codes: 1070, 1095 UKBiobank field 6150 code: 1 See eTable 1 for risk factor codingsShow moreMean = 8.01 years
Sd = 1.04 years
[
  • 6,272 cases
  • , 346,388 controls
]
,
41.8 % Male samples
Mean = 55.9 years
Range = [40.0, 69.0] years		European, African unspecified, NR98.3% White European, 1.7% Black/OtherUKBPCE Prospective Cohort (lipid-lowering treatment performed)
PSS000401Coronary artery disease was defined as myocardial infarction and its related sequelae (coronary angi... oplasty, and coronary artery bypass grafts). ICD-10 codes: I21, I22, I23, I24.1, I25.2 ICD-9 codes: 410, 411, 412, 429.79 OPCS-4 codes: K40.1-4, K41.1-4, K45.1-5, K49.1-2, K49.8-9, K50.2, K75.1-4, K54.8-9 UKBiobank field 20002 code: 1075 UKBiobank field 20004 codes: 1070, 1095 UKBiobank field 6150 code: 1 See eTable 1 for risk factor codingsShow moreMean = 8.01 years
Sd = 1.04 years
[
  • 6,239 cases
  • , 344,491 controls
]
,
41.0 % Male samples
Range = [40.0, 69.0] yearsEuropean, South Asian, African American or Afro-Caribbean, African unspecified, East Asian, Asian unspecified2,332 Africans, 145 Bangladeshi, 3,165 Carribeans, 1,136 Chinese, 3,790 Indians, 1,258 Other Asians, 1,182 Pakistani, 332,326 White Europeans and Unkown ancestryUKBQRISK3 Prospective Cohort/Testing Set (lipid-lowering treatment performed)
PSS010121Coronary artery disease (CAD), ccomprising either non-fatal myocardial infarction, death from corona... ry heart disease or symptomatic stable angina followed by a revascularization procedure, either by percutaneous coronary intervention (PCI), or by coronary artery bypass grafting (CABG) using relevant medical records and ICD codes. All events were adjudicated by two expert. More details in PMID: 33838036Show moreMedian = [10.7, 14.6] years
[
  • 195 cases
  • , 3,188 controls
]
,
45.0 % Male samples
Mean = 52.3 yearsEuropean—CoLausright censored was death or latest evidence of good health, participant with statine therapy at base... line were excludedShow more
PSS010122Coronary artery disease (CAD), ccomprising either non-fatal myocardial infarction, death from corona... ry heart disease or symptomatic stable angina followed by a revascularization procedure, either by percutaneous coronary intervention (PCI), or by coronary artery bypass grafting (CABG) using relevant medical records and ICD codes. All events were adjudicated by two expert. More details in PMID: 33838036Show moreMedian = [10.6, 14.6] years
[
  • 388 cases
  • , 3,830 controls
]
,
47.0 % Male samples
Mean = 53.4 yearsEuropean—CoLausright censored was death or latest evidence of good health
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