Polygenic Score (PGS) ID: PGS001067

Predicted Trait
Reported Trait Processed meat intake
Mapped Trait(s) diet measurement (EFO_0008111)
Additional Trait Information https://biobankengine.stanford.edu/RIVAS_HG19/snpnet/QT_FC1001349
Released in PGS Catalog: Oct. 21, 2021
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Terms and Licenses
PGS obtained from the Catalog should be cited appropriately, and used in accordance with any licensing restrictions set by the authors. See EBI Terms of Use (https://www.ebi.ac.uk/about/terms-of-use/) for additional details.

Score Details

Score Construction
PGS Name GBE_QT_FC1001349
Development Method
Name snpnet
Parameters NR
Variants
Original Genome Build GRCh37
Number of Variants 2,346
Effect Weight Type NR
PGS Source
PGS Catalog Publication (PGP) ID PGP000244
Citation (link to publication) Tanigawa Y et al. PLoS Genet (2022)
Ancestry Distribution
Score Development/Training
European: 100%
269,358 individuals (100%)
PGS Evaluation
European: 40%
African: 20%
East Asian: 20%
South Asian: 20%
5 Sample Sets

Development Samples

Score Development/Training
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Study Identifiers
Sample Numbers
Sample Ancestry
Cohort(s)
Phenotype Definitions & Methods
Age of Study Participants
Participant Follow-up Time
Additional Ancestry Description
Additional Sample/Cohort Information
269,358 individualsEuropeanUKBwhite British ancestry
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Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

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PGS Performance
Metric ID (PPM)
PGS Sample Set ID
(PSS)
Performance Source
Trait
PGS Effect Sizes
(per SD change)
Classification Metrics
Other Metrics
Covariates Included in the Model
PGS Performance:
Other Relevant Information
PPM008093PSS007546|
African Ancestry|
6,311 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Processed meat intake: 0.05609 [0.04522, 0.06695]
Incremental R2 (full-covars): 0.00153
PGS R2 (no covariates): 0.00178 [-0.00027, 0.00382]
age, sex, UKB array type, Genotype PCs
PPM008094PSS007547|
East Asian Ancestry|
1,642 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Processed meat intake: 0.07224 [0.04861, 0.09588]
Incremental R2 (full-covars): -0.0026
PGS R2 (no covariates): 4e-05 [-0.00058, 0.00066]
age, sex, UKB array type, Genotype PCs
PPM008095PSS007548|
European Ancestry|
24,852 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Processed meat intake: 0.10754 [0.10027, 0.11481]
Incremental R2 (full-covars): 0.00194
PGS R2 (no covariates): 0.003 [0.00165, 0.00436]
age, sex, UKB array type, Genotype PCs
PPM008096PSS007549|
South Asian Ancestry|
7,555 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Processed meat intake: 0.10977 [0.09671, 0.12282]
Incremental R2 (full-covars): -0.00173
PGS R2 (no covariates): 1e-05 [-0.00014, 0.00017]
age, sex, UKB array type, Genotype PCs
PPM008097PSS007550|
European Ancestry|
67,321 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Processed meat intake: 0.08633 [0.08228, 0.09039]
Incremental R2 (full-covars): 0.00281
PGS R2 (no covariates): 0.00275 [0.00196, 0.00354]
age, sex, UKB array type, Genotype PCs
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Evaluated Samples

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PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods
Participant Follow-up Time
Sample Numbers
Age of Study Participants
Sample Ancestry
Additional Ancestry Description
Cohort(s)
Additional Sample/Cohort Information
PSS0075466,311 individualsAfrican unspecifiedUKB
PSS0075471,642 individualsEast AsianUKB
PSS00754824,852 individualsEuropeannon-white British ancestryUKB
PSS0075497,555 individualsSouth AsianUKB
PSS00755067,321 individualsEuropeanwhite British ancestryUKBTesting cohort (heldout set)
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