Polygenic Score (PGS) ID: PGS002006

Predicted Trait
Reported Trait Snoring
Mapped Trait(s) snoring measurement (EFO_0008341)
Additional Trait Information physical measures
Released in PGS Catalog: Jan. 10, 2022
Download Score FTP directory
Terms and Licenses
PGS obtained from the Catalog should be cited appropriately, and used in accordance with any licensing restrictions set by the authors. See EBI Terms of Use (https://www.ebi.ac.uk/about/terms-of-use/) for additional details.

Score Details

Score Construction
PGS Name portability-PLR_snoring
Development Method
Name Penalized regression (bigstatsr)
Parameters HapMap3 variants
Variants
Original Genome Build GRCh37
Number of Variants 33,917
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000263
Citation (link to publication) Privé F et al. Am J Hum Genet (2022)
Ancestry Distribution
Score Development/Training
European: 100%
391,124 individuals (100%)
PGS Evaluation
European: 37.5%
African: 25%
East Asian: 12.5%
Greater Middle Eastern: 12.5%
South Asian: 12.5%
8 Sample Sets

Development Samples

Score Development/Training
Study Identifiers Sample Numbers Sample Ancestry Cohort(s) Phenotype Definitions & Methods Age of Study Participants Participant Follow-up Time Additional Ancestry Description Additional Sample/Cohort Information
— 391,124 individuals European UKB — — — UK (+ Ireland) —

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM010922 PSS009491|
European Ancestry|
18,616 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Snoring — — Partial Correlation (partial-r): 0.1113 [0.0971, 0.1255] sex, age, birth date, deprivation index, 16 PCs —
PPM010923 PSS009265|
European Ancestry|
3,654 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Snoring — — Partial Correlation (partial-r): 0.1078 [0.0755, 0.1398] sex, age, birth date, deprivation index, 16 PCs —
PPM010924 PSS008819|
European Ancestry|
6,027 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Snoring — — Partial Correlation (partial-r): 0.0992 [0.0741, 0.1242] sex, age, birth date, deprivation index, 16 PCs —
PPM010925 PSS008593|
Greater Middle Eastern Ancestry|
1,011 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Snoring — — Partial Correlation (partial-r): 0.0834 [0.0212, 0.1449] sex, age, birth date, deprivation index, 16 PCs —
PPM010927 PSS008147|
East Asian Ancestry|
1,576 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Snoring — — Partial Correlation (partial-r): 0.0748 [0.0252, 0.1241] sex, age, birth date, deprivation index, 16 PCs —
PPM010929 PSS009039|
African Ancestry|
3,448 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Snoring — — Partial Correlation (partial-r): 0.0557 [0.0223, 0.089] sex, age, birth date, deprivation index, 16 PCs —
PPM010926 PSS008371|
South Asian Ancestry|
5,655 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Snoring — — Partial Correlation (partial-r): 0.0816 [0.0556, 0.1075] sex, age, birth date, deprivation index, 16 PCs —
PPM010928 PSS007935|
African Ancestry|
2,178 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Snoring — — Partial Correlation (partial-r): 0.07 [0.0279, 0.1119] sex, age, birth date, deprivation index, 16 PCs —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS009039 — — 3,448 individuals — African unspecified Nigeria (West Africa) UKB —
PSS008593 — — 1,011 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS009265 — — 3,654 individuals — European Poland (NE Europe) UKB —
PSS008819 — — 6,027 individuals — European Italy (South Europe) UKB —
PSS008147 — — 1,576 individuals — East Asian China (East Asia) UKB —
PSS009491 — — 18,616 individuals — European UK (+ Ireland) UKB —
PSS008371 — — 5,655 individuals — South Asian India (South Asia) UKB —
PSS007935 — — 2,178 individuals — African American or Afro-Caribbean Carribean UKB —