Predicted Trait | |
Reported Trait | Skin color |
Mapped Trait(s) | skin pigmentation (EFO_0003784) |
Additional Trait Information | physical measures |
Score Construction | |
PGS Name | portability-ldpred2_darker_skin0 |
Development Method | |
Name | LDpred2 (bigsnpr) |
Parameters | LDpred2-auto using HapMap3 variants |
Variants | |
Original Genome Build | GRCh37 |
Number of Variants | 275,831 |
Effect Weight Type | beta |
PGS Source | |
PGS Catalog Publication (PGP) ID | PGP000263 |
Citation (link to publication) | Privé F et al. Am J Hum Genet (2022) |
Study Identifiers | Sample Numbers | Sample Ancestry | Cohort(s) | Phenotype Definitions & Methods | Age of Study Participants | Participant Follow-up Time | Additional Ancestry Description | Additional Sample/Cohort Information |
---|---|---|---|---|---|---|---|---|
— | 391,124 individuals | European | UKB | — | — | — | UK (+ Ireland) | — |
PGS Performance Metric ID (PPM) |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
---|---|---|---|---|---|---|---|---|
PPM011735 | PSS009393| European Ancestry| 19,738 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin colour | — | — | Partial Correlation (partial-r): 0.3849 [0.3729, 0.3967] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM011736 | PSS009167| European Ancestry| 4,029 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin colour | — | — | Partial Correlation (partial-r): 0.3197 [0.2916, 0.3472] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM011737 | PSS008721| European Ancestry| 6,521 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin colour | — | — | Partial Correlation (partial-r): 0.3242 [0.3023, 0.3458] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM011738 | PSS008495| Greater Middle Eastern Ancestry| 1,058 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin colour | — | — | Partial Correlation (partial-r): 0.2964 [0.2399, 0.351] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM011739 | PSS008273| South Asian Ancestry| 6,068 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin colour | — | — | Partial Correlation (partial-r): 0.1163 [0.0914, 0.1411] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM011740 | PSS008050| East Asian Ancestry| 1,506 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin colour | — | — | Partial Correlation (partial-r): 0.0115 [-0.0394, 0.0623] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM011741 | PSS007837| African Ancestry| 2,401 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin colour | — | — | Partial Correlation (partial-r): 0.0842 [0.0442, 0.1239] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM011742 | PSS008941| African Ancestry| 3,778 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin colour | — | — | Partial Correlation (partial-r): 0.0232 [-0.0088, 0.0551] | sex, age, birth date, deprivation index, 16 PCs | — |
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
---|---|---|---|---|---|---|---|---|
PSS008941 | — | — | 3,778 individuals | — | African unspecified | Nigeria (West Africa) | UKB | — |
PSS008495 | — | — | 1,058 individuals | — | Greater Middle Eastern (Middle Eastern, North African or Persian) | Iran (Middle East) | UKB | — |
PSS009167 | — | — | 4,029 individuals | — | European | Poland (NE Europe) | UKB | — |
PSS008721 | — | — | 6,521 individuals | — | European | Italy (South Europe) | UKB | — |
PSS009393 | — | — | 19,738 individuals | — | European | UK (+ Ireland) | UKB | — |
PSS008273 | — | — | 6,068 individuals | — | South Asian | India (South Asia) | UKB | — |
PSS008050 | — | — | 1,506 individuals | — | East Asian | China (East Asia) | UKB | — |
PSS007837 | — | — | 2,401 individuals | — | African American or Afro-Caribbean | Carribean | UKB | — |