Experimental Factor Ontology (EFO) Information | |
Identifier | EFO_0003784 |
Description | Coloration of the skin. | Trait category |
Other trait
|
Synonyms |
3 synonyms
|
Mapped terms |
5 mapped terms
|
Child trait(s) | suntan |
Polygenic Score ID & Name | PGS Publication ID (PGP) | Reported Trait | Mapped Trait(s) (Ontology) | Number of Variants |
Ancestry distribution GWAS Dev Eval |
Scoring File (FTP Link) |
---|---|---|---|---|---|---|
PGS001244 (GBE_BIN_FC30001727) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Ease of skin tanning (get mildly or occasionally tanned) | suntan | 958 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001244/ScoringFiles/PGS001244.txt.gz |
PGS001245 (GBE_BIN_FC20001727) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Ease of skin tanning (get moderately tanned) | suntan | 2,693 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001245/ScoringFiles/PGS001245.txt.gz |
PGS001246 (GBE_BIN_FC10001727) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Ease of skin tanning (get very tanned) | suntan | 4,130 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001246/ScoringFiles/PGS001246.txt.gz |
PGS001247 (GBE_BIN_FC40001727) |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Ease of skin tanning (never tan, only burn) | suntan | 3,159 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001247/ScoringFiles/PGS001247.txt.gz |
PGS001897 (portability-PLR_darker_skin0) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Skin color | skin pigmentation | 15,817 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001897/ScoringFiles/PGS001897.txt.gz |
PGS001937 (portability-PLR_less_tanned) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Ease of skin tanning | suntan | 16,197 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001937/ScoringFiles/PGS001937.txt.gz |
PGS002110 (portability-ldpred2_darker_skin0) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Skin color | skin pigmentation | 275,831 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002110/ScoringFiles/PGS002110.txt.gz |
PGS002155 (portability-ldpred2_less_tanned) |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Ease of skin tanning | suntan | 240,701 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002155/ScoringFiles/PGS002155.txt.gz |
PGS002350 (pigment_TANNING.BOLT-LMM) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Tanning | suntan | 1,109,311 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002350/ScoringFiles/PGS002350.txt.gz |
PGS002422 (pigment_TANNING.P+T.0.0001) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Tanning | suntan | 8,273 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002422/ScoringFiles/PGS002422.txt.gz |
PGS002471 (pigment_TANNING.P+T.0.001) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Tanning | suntan | 20,040 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002471/ScoringFiles/PGS002471.txt.gz |
PGS002520 (pigment_TANNING.P+T.0.01) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Tanning | suntan | 100,837 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002520/ScoringFiles/PGS002520.txt.gz |
PGS002569 (pigment_TANNING.P+T.1e-06) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Tanning | suntan | 4,792 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002569/ScoringFiles/PGS002569.txt.gz |
PGS002618 (pigment_TANNING.P+T.5e-08) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Tanning | suntan | 4,026 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002618/ScoringFiles/PGS002618.txt.gz |
PGS002667 (pigment_TANNING.PolyFun-pred) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Tanning | suntan | 123,613 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002667/ScoringFiles/PGS002667.txt.gz |
PGS002716 (pigment_TANNING.SBayesR) |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Tanning | suntan | 947,237 | - |
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002716/ScoringFiles/PGS002716.txt.gz |
PGS Performance Metric ID (PPM) |
Evaluated Score |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
---|---|---|---|---|---|---|---|---|---|
PPM008729 | PGS001244 (GBE_BIN_FC30001727) |
PSS003879| African Ancestry| 4,524 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ease of skin tanning (Get mildly or occasionally tanned) | — | AUROC: 0.52345 [0.50398, 0.54292] | R²: 0.00289 Incremental AUROC (full-covars): -0.04291 PGS R2 (no covariates): 0.00485 PGS AUROC (no covariates): 0.46513 [0.44563, 0.48463] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
PPM008730 | PGS001244 (GBE_BIN_FC30001727) |
PSS003880| East Asian Ancestry| 1,541 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ease of skin tanning (Get mildly or occasionally tanned) | — | AUROC: 0.54571 [0.50672, 0.5847] | PGS R2 (no covariates): 0.00029 R²: 0.01015 Incremental AUROC (full-covars): -0.01074 PGS AUROC (no covariates): 0.50235 [0.46279, 0.54191] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
PPM008731 | PGS001244 (GBE_BIN_FC30001727) |
PSS003881| European Ancestry| 24,421 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ease of skin tanning (Get mildly or occasionally tanned) | — | AUROC: 0.64487 [0.63683, 0.65291] | R²: 0.06277 Incremental AUROC (full-covars): 0.03781 PGS R2 (no covariates): 0.05363 PGS AUROC (no covariates): 0.63901 [0.631, 0.64703] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
PPM008732 | PGS001244 (GBE_BIN_FC30001727) |
PSS003882| South Asian Ancestry| 6,616 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ease of skin tanning (Get mildly or occasionally tanned) | — | AUROC: 0.5248 [0.50879, 0.54081] | R²: 0.00212 Incremental AUROC (full-covars): -0.01511 PGS R2 (no covariates): 0.00013 PGS AUROC (no covariates): 0.50088 [0.48459, 0.51717] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
PPM008733 | PGS001244 (GBE_BIN_FC30001727) |
PSS003883| European Ancestry| 66,187 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ease of skin tanning (Get mildly or occasionally tanned) | — | AUROC: 0.63688 [0.63202, 0.64174] | R²: 0.05636 Incremental AUROC (full-covars): 0.0631 PGS R2 (no covariates): 0.04114 PGS AUROC (no covariates): 0.61836 [0.61342, 0.62331] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
PPM008734 | PGS001245 (GBE_BIN_FC20001727) |
PSS003820| African Ancestry| 4,524 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ease of skin tanning (Get moderately tanned) | — | AUROC: 0.56845 [0.54941, 0.58748] | R²: 0.0181 Incremental AUROC (full-covars): -0.00634 PGS R2 (no covariates): 0.00058 PGS AUROC (no covariates): 0.4935 [0.47406, 0.51294] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
PPM008735 | PGS001245 (GBE_BIN_FC20001727) |
PSS003821| East Asian Ancestry| 1,541 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ease of skin tanning (Get moderately tanned) | — | AUROC: 0.56854 [0.53942, 0.59766] | R²: 0.0235 Incremental AUROC (full-covars): -0.00697 PGS R2 (no covariates): 3e-05 PGS AUROC (no covariates): 0.50505 [0.47505, 0.53504] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
PPM008736 | PGS001245 (GBE_BIN_FC20001727) |
PSS003822| European Ancestry| 24,421 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ease of skin tanning (Get moderately tanned) | — | AUROC: 0.60803 [0.60093, 0.61513] | R²: 0.0505 Incremental AUROC (full-covars): 0.02684 PGS R2 (no covariates): 0.04554 PGS AUROC (no covariates): 0.59926 [0.59214, 0.60639] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
PPM008737 | PGS001245 (GBE_BIN_FC20001727) |
PSS003823| South Asian Ancestry| 6,616 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ease of skin tanning (Get moderately tanned) | — | AUROC: 0.53215 [0.51774, 0.54657] | R²: 0.00473 Incremental AUROC (full-covars): -0.01571 PGS R2 (no covariates): 0.00011 PGS AUROC (no covariates): 0.4952 [0.4807, 0.5097] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
PPM008738 | PGS001245 (GBE_BIN_FC20001727) |
PSS003824| European Ancestry| 66,187 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ease of skin tanning (Get moderately tanned) | — | AUROC: 0.59038 [0.58606, 0.5947] | R²: 0.03719 Incremental AUROC (full-covars): 0.0541 PGS R2 (no covariates): 0.03521 PGS AUROC (no covariates): 0.58661 [0.58228, 0.59094] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
PPM008739 | PGS001246 (GBE_BIN_FC10001727) |
PSS003706| African Ancestry| 4,524 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ease of skin tanning (Get very tanned) | — | AUROC: 0.55472 [0.5369, 0.57253] | R²: 0.00767 Incremental AUROC (full-covars): -0.09744 PGS R2 (no covariates): 0.02303 PGS AUROC (no covariates): 0.42303 [0.40544, 0.44063] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
PPM008740 | PGS001246 (GBE_BIN_FC10001727) |
PSS003707| East Asian Ancestry| 1,541 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ease of skin tanning (Get very tanned) | — | AUROC: 0.57445 [0.54548, 0.60341] | R²: 0.0252 Incremental AUROC (full-covars): 0.0116 PGS R2 (no covariates): 0.00504 PGS AUROC (no covariates): 0.53511 [0.50559, 0.56464] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
PPM008741 | PGS001246 (GBE_BIN_FC10001727) |
PSS003708| European Ancestry| 24,421 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ease of skin tanning (Get very tanned) | — | AUROC: 0.74853 [0.74163, 0.75543] | R²: 0.19694 Incremental AUROC (full-covars): 0.07826 PGS R2 (no covariates): 0.20123 PGS AUROC (no covariates): 0.75019 [0.74322, 0.75717] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
PPM008742 | PGS001246 (GBE_BIN_FC10001727) |
PSS003709| South Asian Ancestry| 6,616 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ease of skin tanning (Get very tanned) | — | AUROC: 0.53071 [0.51584, 0.54558] | R²: 0.00488 Incremental AUROC (full-covars): -0.02206 PGS R2 (no covariates): 0.00175 PGS AUROC (no covariates): 0.51457 [0.4998, 0.52934] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
PPM008743 | PGS001246 (GBE_BIN_FC10001727) |
PSS003710| European Ancestry| 66,187 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ease of skin tanning (Get very tanned) | — | AUROC: 0.73548 [0.73096, 0.74] | R²: 0.17513 Incremental AUROC (full-covars): 0.13981 PGS R2 (no covariates): 0.14977 PGS AUROC (no covariates): 0.71732 [0.71263, 0.72202] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
PPM008744 | PGS001247 (GBE_BIN_FC40001727) |
PSS003924| African Ancestry| 4,524 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ease of skin tanning (Never tan, only burn) | — | AUROC: 0.72336 [0.70495, 0.74178] | R²: 0.1468 Incremental AUROC (full-covars): -0.02841 PGS R2 (no covariates): 0.03694 PGS AUROC (no covariates): 0.40146 [0.38146, 0.42147] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
PPM008745 | PGS001247 (GBE_BIN_FC40001727) |
PSS003925| East Asian Ancestry| 1,541 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ease of skin tanning (Never tan, only burn) | — | AUROC: 0.60911 [0.55312, 0.6651] | R²: 0.06219 Incremental AUROC (full-covars): -0.04068 PGS R2 (no covariates): 0.00142 PGS AUROC (no covariates): 0.46835 [0.41763, 0.51907] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
PPM008746 | PGS001247 (GBE_BIN_FC40001727) |
PSS003926| European Ancestry| 24,421 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ease of skin tanning (Never tan, only burn) | — | AUROC: 0.7732 [0.76576, 0.78064] | R²: 0.23458 Incremental AUROC (full-covars): 0.08314 PGS R2 (no covariates): 0.24179 PGS AUROC (no covariates): 0.77686 [0.76951, 0.78422] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
PPM008747 | PGS001247 (GBE_BIN_FC40001727) |
PSS003927| South Asian Ancestry| 6,616 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ease of skin tanning (Never tan, only burn) | — | AUROC: 0.54182 [0.51791, 0.56574] | R²: 0.00258 Incremental AUROC (full-covars): -0.04265 PGS R2 (no covariates): 0.00055 PGS AUROC (no covariates): 0.48795 [0.46261, 0.51329] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
PPM008748 | PGS001247 (GBE_BIN_FC40001727) |
PSS003928| European Ancestry| 66,187 individuals |
PGP000244 | Tanigawa Y et al. PLoS Genet (2022) |
Reported Trait: Ease of skin tanning (Never tan, only burn) | — | AUROC: 0.74303 [0.7382, 0.74787] | R²: 0.18357 Incremental AUROC (full-covars): 0.17233 PGS R2 (no covariates): 0.18165 PGS AUROC (no covariates): 0.74085 [0.73597, 0.74572] |
age, sex, UKB array type, Genotype PCs | Full Model & PGS R2 is estimated using Nagelkerke's method |
PPM010059 | PGS001897 (portability-PLR_darker_skin0) |
PSS009393| European Ancestry| 19,738 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin colour | — | — | Partial Correlation (partial-r): 0.387 [0.375, 0.3988] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM010060 | PGS001897 (portability-PLR_darker_skin0) |
PSS009167| European Ancestry| 4,029 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin colour | — | — | Partial Correlation (partial-r): 0.3235 [0.2955, 0.3509] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM010061 | PGS001897 (portability-PLR_darker_skin0) |
PSS008721| European Ancestry| 6,521 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin colour | — | — | Partial Correlation (partial-r): 0.326 [0.3041, 0.3476] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM010063 | PGS001897 (portability-PLR_darker_skin0) |
PSS008273| South Asian Ancestry| 6,068 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin colour | — | — | Partial Correlation (partial-r): 0.1171 [0.0921, 0.1418] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM010064 | PGS001897 (portability-PLR_darker_skin0) |
PSS008050| East Asian Ancestry| 1,506 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin colour | — | — | Partial Correlation (partial-r): 0.0091 [-0.0418, 0.0599] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM010065 | PGS001897 (portability-PLR_darker_skin0) |
PSS007837| African Ancestry| 2,401 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin colour | — | — | Partial Correlation (partial-r): 0.0775 [0.0374, 0.1173] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM010066 | PGS001897 (portability-PLR_darker_skin0) |
PSS008941| African Ancestry| 3,778 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin colour | — | — | Partial Correlation (partial-r): 0.0247 [-0.0073, 0.0567] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM010062 | PGS001897 (portability-PLR_darker_skin0) |
PSS008495| Greater Middle Eastern Ancestry| 1,058 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin colour | — | — | Partial Correlation (partial-r): 0.2918 [0.2352, 0.3465] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM010371 | PGS001937 (portability-PLR_less_tanned) |
PSS009424| European Ancestry| 19,578 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ease of skin tanning | — | — | Partial Correlation (partial-r): 0.4089 [0.3972, 0.4205] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM010372 | PGS001937 (portability-PLR_less_tanned) |
PSS009198| European Ancestry| 3,995 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ease of skin tanning | — | — | Partial Correlation (partial-r): 0.3298 [0.3018, 0.3572] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM010373 | PGS001937 (portability-PLR_less_tanned) |
PSS008752| European Ancestry| 6,490 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ease of skin tanning | — | — | Partial Correlation (partial-r): 0.3092 [0.287, 0.3311] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM010374 | PGS001937 (portability-PLR_less_tanned) |
PSS008526| Greater Middle Eastern Ancestry| 996 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ease of skin tanning | — | — | Partial Correlation (partial-r): 0.0834 [0.0207, 0.1454] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM010375 | PGS001937 (portability-PLR_less_tanned) |
PSS008304| South Asian Ancestry| 5,414 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ease of skin tanning | — | — | Partial Correlation (partial-r): 0.0218 [-0.0049, 0.0484] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM010376 | PGS001937 (portability-PLR_less_tanned) |
PSS008081| East Asian Ancestry| 1,651 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ease of skin tanning | — | — | Partial Correlation (partial-r): -0.0042 [-0.0527, 0.0443] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM010377 | PGS001937 (portability-PLR_less_tanned) |
PSS007868| African Ancestry| 2,004 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ease of skin tanning | — | — | Partial Correlation (partial-r): -0.0432 | sex, age, birth date, deprivation index, 16 PCs | — |
PPM010378 | PGS001937 (portability-PLR_less_tanned) |
PSS008972| African Ancestry| 2,347 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ease of skin tanning | — | — | Partial Correlation (partial-r): -0.0234 [-0.064, 0.0172] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM011735 | PGS002110 (portability-ldpred2_darker_skin0) |
PSS009393| European Ancestry| 19,738 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin colour | — | — | Partial Correlation (partial-r): 0.3849 [0.3729, 0.3967] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM011736 | PGS002110 (portability-ldpred2_darker_skin0) |
PSS009167| European Ancestry| 4,029 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin colour | — | — | Partial Correlation (partial-r): 0.3197 [0.2916, 0.3472] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM011737 | PGS002110 (portability-ldpred2_darker_skin0) |
PSS008721| European Ancestry| 6,521 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin colour | — | — | Partial Correlation (partial-r): 0.3242 [0.3023, 0.3458] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM011738 | PGS002110 (portability-ldpred2_darker_skin0) |
PSS008495| Greater Middle Eastern Ancestry| 1,058 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin colour | — | — | Partial Correlation (partial-r): 0.2964 [0.2399, 0.351] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM011739 | PGS002110 (portability-ldpred2_darker_skin0) |
PSS008273| South Asian Ancestry| 6,068 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin colour | — | — | Partial Correlation (partial-r): 0.1163 [0.0914, 0.1411] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM011740 | PGS002110 (portability-ldpred2_darker_skin0) |
PSS008050| East Asian Ancestry| 1,506 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin colour | — | — | Partial Correlation (partial-r): 0.0115 [-0.0394, 0.0623] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM011741 | PGS002110 (portability-ldpred2_darker_skin0) |
PSS007837| African Ancestry| 2,401 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin colour | — | — | Partial Correlation (partial-r): 0.0842 [0.0442, 0.1239] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM011742 | PGS002110 (portability-ldpred2_darker_skin0) |
PSS008941| African Ancestry| 3,778 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Skin colour | — | — | Partial Correlation (partial-r): 0.0232 [-0.0088, 0.0551] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM012090 | PGS002155 (portability-ldpred2_less_tanned) |
PSS008526| Greater Middle Eastern Ancestry| 996 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ease of skin tanning | — | — | Partial Correlation (partial-r): 0.0806 [0.0179, 0.1426] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM012087 | PGS002155 (portability-ldpred2_less_tanned) |
PSS009424| European Ancestry| 19,578 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ease of skin tanning | — | — | Partial Correlation (partial-r): 0.4051 [0.3933, 0.4168] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM012088 | PGS002155 (portability-ldpred2_less_tanned) |
PSS009198| European Ancestry| 3,995 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ease of skin tanning | — | — | Partial Correlation (partial-r): 0.3281 [0.3, 0.3555] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM012089 | PGS002155 (portability-ldpred2_less_tanned) |
PSS008752| European Ancestry| 6,490 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ease of skin tanning | — | — | Partial Correlation (partial-r): 0.3057 [0.2834, 0.3276] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM012091 | PGS002155 (portability-ldpred2_less_tanned) |
PSS008304| South Asian Ancestry| 5,414 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ease of skin tanning | — | — | Partial Correlation (partial-r): 0.0246 [-0.0021, 0.0512] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM012092 | PGS002155 (portability-ldpred2_less_tanned) |
PSS008081| East Asian Ancestry| 1,651 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ease of skin tanning | — | — | Partial Correlation (partial-r): -0.0075 [-0.056, 0.041] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM012093 | PGS002155 (portability-ldpred2_less_tanned) |
PSS007868| African Ancestry| 2,004 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ease of skin tanning | — | — | Partial Correlation (partial-r): -0.0465 [-0.0903, -0.0025] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM012094 | PGS002155 (portability-ldpred2_less_tanned) |
PSS008972| African Ancestry| 2,347 individuals |
PGP000263 | Privé F et al. Am J Hum Genet (2022) |
Reported Trait: Ease of skin tanning | — | — | Partial Correlation (partial-r): -0.0194 [-0.06, 0.0212] | sex, age, birth date, deprivation index, 16 PCs | — |
PPM013115 | PGS002350 (pigment_TANNING.BOLT-LMM) |
PSS009843| African Ancestry| 4,649 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013164 | PGS002350 (pigment_TANNING.BOLT-LMM) |
PSS009844| East Asian Ancestry| 864 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model vs. covariates alone): 0.0014 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013213 | PGS002350 (pigment_TANNING.BOLT-LMM) |
PSS009845| European Ancestry| 42,556 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model vs. covariates alone): 0.1206 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013262 | PGS002350 (pigment_TANNING.BOLT-LMM) |
PSS009846| South Asian Ancestry| 6,976 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model vs. covariates alone): 0.0003 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013452 | PGS002422 (pigment_TANNING.P+T.0.0001) |
PSS009844| East Asian Ancestry| 864 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013501 | PGS002422 (pigment_TANNING.P+T.0.0001) |
PSS009845| European Ancestry| 42,556 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model vs. covariates alone): 0.0722 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013550 | PGS002422 (pigment_TANNING.P+T.0.0001) |
PSS009846| South Asian Ancestry| 6,976 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model vs. covariates alone): 0.0001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013403 | PGS002422 (pigment_TANNING.P+T.0.0001) |
PSS009843| African Ancestry| 4,649 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model vs. covariates alone): 0.0008 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013599 | PGS002471 (pigment_TANNING.P+T.0.001) |
PSS009843| African Ancestry| 4,649 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013648 | PGS002471 (pigment_TANNING.P+T.0.001) |
PSS009844| East Asian Ancestry| 864 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model vs. covariates alone): 0.0011 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013697 | PGS002471 (pigment_TANNING.P+T.0.001) |
PSS009845| European Ancestry| 42,556 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model vs. covariates alone): 0.0729 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013746 | PGS002471 (pigment_TANNING.P+T.0.001) |
PSS009846| South Asian Ancestry| 6,976 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model vs. covariates alone): 0.0001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013795 | PGS002520 (pigment_TANNING.P+T.0.01) |
PSS009843| African Ancestry| 4,649 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model vs. covariates alone): 0.0003 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013844 | PGS002520 (pigment_TANNING.P+T.0.01) |
PSS009844| East Asian Ancestry| 864 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model vs. covariates alone): 0.0015 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013893 | PGS002520 (pigment_TANNING.P+T.0.01) |
PSS009845| European Ancestry| 42,556 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model vs. covariates alone): 0.0582 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013942 | PGS002520 (pigment_TANNING.P+T.0.01) |
PSS009846| South Asian Ancestry| 6,976 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model vs. covariates alone): 0.0003 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM014040 | PGS002569 (pigment_TANNING.P+T.1e-06) |
PSS009844| East Asian Ancestry| 864 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM013991 | PGS002569 (pigment_TANNING.P+T.1e-06) |
PSS009843| African Ancestry| 4,649 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model vs. covariates alone): 0.0001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM014089 | PGS002569 (pigment_TANNING.P+T.1e-06) |
PSS009845| European Ancestry| 42,556 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model vs. covariates alone): 0.0703 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM014138 | PGS002569 (pigment_TANNING.P+T.1e-06) |
PSS009846| South Asian Ancestry| 6,976 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model vs. covariates alone): 0.0001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM014187 | PGS002618 (pigment_TANNING.P+T.5e-08) |
PSS009843| African Ancestry| 4,649 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM014236 | PGS002618 (pigment_TANNING.P+T.5e-08) |
PSS009844| East Asian Ancestry| 864 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM014285 | PGS002618 (pigment_TANNING.P+T.5e-08) |
PSS009845| European Ancestry| 42,556 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model vs. covariates alone): 0.0696 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM014334 | PGS002618 (pigment_TANNING.P+T.5e-08) |
PSS009846| South Asian Ancestry| 6,976 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model vs. covariates alone): 0.0001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM014530 | PGS002667 (pigment_TANNING.PolyFun-pred) |
PSS009846| South Asian Ancestry| 6,976 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0001 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See pigment_TANNING.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
PPM014383 | PGS002667 (pigment_TANNING.PolyFun-pred) |
PSS009843| African Ancestry| 4,649 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See pigment_TANNING.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
PPM014432 | PGS002667 (pigment_TANNING.PolyFun-pred) |
PSS009844| East Asian Ancestry| 864 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.0015 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See pigment_TANNING.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
PPM014481 | PGS002667 (pigment_TANNING.PolyFun-pred) |
PSS009845| European Ancestry| 42,556 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model when combined with BOLT-LMM vs. covariates alone): 0.1326 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | See pigment_TANNING.mixweights file at http://data.broadinstitute.org/alkesgroup/polypred_results for combination weights |
PPM014579 | PGS002716 (pigment_TANNING.SBayesR) |
PSS009843| African Ancestry| 4,649 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model vs. covariates alone): 0.0 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM014628 | PGS002716 (pigment_TANNING.SBayesR) |
PSS009844| East Asian Ancestry| 864 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model vs. covariates alone): 0.0019 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM014677 | PGS002716 (pigment_TANNING.SBayesR) |
PSS009845| European Ancestry| 42,556 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model vs. covariates alone): 0.0972 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PPM014726 | PGS002716 (pigment_TANNING.SBayesR) |
PSS009846| South Asian Ancestry| 6,976 individuals |
PGP000332 | Weissbrod O et al. Nat Genet (2022) |
Reported Trait: Tanning | — | — | Incremental R2 (full model vs. covariates alone): 0.0003 | age, sex, age*sex, assessment center, genotyping array, 10 PCs | — |
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
---|---|---|---|---|---|---|---|---|
PSS008526 | — | — | 996 individuals | — | Greater Middle Eastern (Middle Eastern, North African or Persian) | Iran (Middle East) | UKB | — |
PSS009167 | — | — | 4,029 individuals | — | European | Poland (NE Europe) | UKB | — |
PSS009424 | — | — | 19,578 individuals | — | European | UK (+ Ireland) | UKB | — |
PSS008273 | — | — | 6,068 individuals | — | South Asian | India (South Asia) | UKB | — |
PSS003924 | — | — | [
|
— | African unspecified | — | UKB | — |
PSS003925 | — | — | [
|
— | East Asian | — | UKB | — |
PSS003926 | — | — | [
|
— | European | non-white British ancestry | UKB | — |
PSS003927 | — | — | [
|
— | South Asian | — | UKB | — |
PSS003928 | — | — | [
|
— | European | white British ancestry | UKB | Testing cohort (heldout set) |
PSS008941 | — | — | 3,778 individuals | — | African unspecified | Nigeria (West Africa) | UKB | — |
PSS009198 | — | — | 3,995 individuals | — | European | Poland (NE Europe) | UKB | — |
PSS008304 | — | — | 5,414 individuals | — | South Asian | India (South Asia) | UKB | — |
PSS008050 | — | — | 1,506 individuals | — | East Asian | China (East Asia) | UKB | — |
PSS003820 | — | — | [
|
— | African unspecified | — | UKB | — |
PSS003821 | — | — | [
|
— | East Asian | — | UKB | — |
PSS003822 | — | — | [
|
— | European | non-white British ancestry | UKB | — |
PSS003823 | — | — | [
|
— | South Asian | — | UKB | — |
PSS003824 | — | — | [
|
— | European | white British ancestry | UKB | Testing cohort (heldout set) |
PSS003706 | — | — | [
|
— | African unspecified | — | UKB | — |
PSS003707 | — | — | [
|
— | East Asian | — | UKB | — |
PSS003708 | — | — | [
|
— | European | non-white British ancestry | UKB | — |
PSS003709 | — | — | [
|
— | South Asian | — | UKB | — |
PSS003710 | — | — | [
|
— | European | white British ancestry | UKB | Testing cohort (heldout set) |
PSS008972 | — | — | 2,347 individuals | — | African unspecified | Nigeria (West Africa) | UKB | — |
PSS008721 | — | — | 6,521 individuals | — | European | Italy (South Europe) | UKB | — |
PSS008081 | — | — | 1,651 individuals | — | East Asian | China (East Asia) | UKB | — |
PSS007837 | — | — | 2,401 individuals | — | African American or Afro-Caribbean | Carribean | UKB | — |
PSS009843 | — | — | 4,649 individuals | — | African unspecified | — | UKB | — |
PSS009844 | — | — | 864 individuals | — | East Asian | — | UKB | — |
PSS009845 | — | — | 42,556 individuals | — | European | Non-British European | UKB | — |
PSS009846 | — | — | 6,976 individuals | — | South Asian | — | UKB | — |
PSS003879 | — | — | [
|
— | African unspecified | — | UKB | — |
PSS003880 | — | — | [
|
— | East Asian | — | UKB | — |
PSS003881 | — | — | [
|
— | European | non-white British ancestry | UKB | — |
PSS003882 | — | — | [
|
— | South Asian | — | UKB | — |
PSS003883 | — | — | [
|
— | European | white British ancestry | UKB | Testing cohort (heldout set) |
PSS009393 | — | — | 19,738 individuals | — | European | UK (+ Ireland) | UKB | — |
PSS008495 | — | — | 1,058 individuals | — | Greater Middle Eastern (Middle Eastern, North African or Persian) | Iran (Middle East) | UKB | — |
PSS008752 | — | — | 6,490 individuals | — | European | Italy (South Europe) | UKB | — |
PSS007868 | — | — | 2,004 individuals | — | African American or Afro-Caribbean | Carribean | UKB | — |