Polygenic Score (PGS) ID: PGS002139

Predicted Trait
Reported Trait Time spent watching television (TV) or using computer
Mapped Trait(s) lifestyle measurement (EFO_0010724)
Additional Trait Information lifestyle and environment
Released in PGS Catalog: Jan. 10, 2022
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Score Details

Score Construction
PGS Name portability-ldpred2_geek_time
Development Method
Name LDpred2 (bigsnpr)
Parameters LDpred2-auto using HapMap3 variants
Variants
Original Genome Build GRCh37
Number of Variants 956,532
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000263
Citation (link to publication) Privé F et al. Am J Hum Genet (2022)
Ancestry Distribution
Score Development/Training
European: 100%
391,124 individuals (100%)
PGS Evaluation
European: 37.5%
African: 25%
East Asian: 12.5%
Greater Middle Eastern: 12.5%
South Asian: 12.5%
8 Sample Sets

Development Samples

Score Development/Training
Study Identifiers Sample Numbers Sample Ancestry Cohort(s) Phenotype Definitions & Methods Age of Study Participants Participant Follow-up Time Additional Ancestry Description Additional Sample/Cohort Information
— 391,124 individuals European UKB — — — UK (+ Ireland) —

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM011959 PSS009409|
European Ancestry|
19,674 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Time spent watching television (TV) or using computer — — Partial Correlation (partial-r): 0.1859 [0.1723, 0.1993] sex, age, birth date, deprivation index, 16 PCs —
PPM011960 PSS009183|
European Ancestry|
4,027 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Time spent watching television (TV) or using computer — — Partial Correlation (partial-r): 0.1371 [0.1066, 0.1673] sex, age, birth date, deprivation index, 16 PCs —
PPM011961 PSS008737|
European Ancestry|
6,466 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Time spent watching television (TV) or using computer — — Partial Correlation (partial-r): 0.1546 [0.1307, 0.1784] sex, age, birth date, deprivation index, 16 PCs —
PPM011962 PSS008511|
Greater Middle Eastern Ancestry|
1,099 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Time spent watching television (TV) or using computer — — Partial Correlation (partial-r): 0.1307 [0.0715, 0.1889] sex, age, birth date, deprivation index, 16 PCs —
PPM011963 PSS008289|
South Asian Ancestry|
5,720 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Time spent watching television (TV) or using computer — — Partial Correlation (partial-r): 0.0943 [0.0685, 0.1199] sex, age, birth date, deprivation index, 16 PCs —
PPM011964 PSS008066|
East Asian Ancestry|
1,721 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Time spent watching television (TV) or using computer — — Partial Correlation (partial-r): 0.0539 [0.0064, 0.1012] sex, age, birth date, deprivation index, 16 PCs —
PPM011965 PSS007853|
African Ancestry|
2,285 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Time spent watching television (TV) or using computer — — Partial Correlation (partial-r): 0.0537 [0.0126, 0.0947] sex, age, birth date, deprivation index, 16 PCs —
PPM011966 PSS008957|
African Ancestry|
3,550 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Time spent watching television (TV) or using computer — — Partial Correlation (partial-r): 0.0314 [-0.0016, 0.0643] sex, age, birth date, deprivation index, 16 PCs —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS009183 — — 4,027 individuals — European Poland (NE Europe) UKB —
PSS007853 — — 2,285 individuals — African American or Afro-Caribbean Carribean UKB —
PSS008289 — — 5,720 individuals — South Asian India (South Asia) UKB —
PSS008957 — — 3,550 individuals — African unspecified Nigeria (West Africa) UKB —
PSS009409 — — 19,674 individuals — European UK (+ Ireland) UKB —
PSS008511 — — 1,099 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS008737 — — 6,466 individuals — European Italy (South Europe) UKB —
PSS008066 — — 1,721 individuals — East Asian China (East Asia) UKB —