Polygenic Score (PGS) ID: PGS002210

Predicted Trait
Reported Trait Use of sun/uv protection
Mapped Trait(s) sun exposure measurement (EFO_0010729)
Additional Trait Information lifestyle and environment
Released in PGS Catalog: Jan. 10, 2022
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Score Details

Score Construction
PGS Name portability-ldpred2_more_sunscreen
Development Method
Name LDpred2 (bigsnpr)
Parameters LDpred2-auto using HapMap3 variants
Variants
Original Genome Build GRCh37
Number of Variants 821,654
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000263
Citation (link to publication) Privé F et al. Am J Hum Genet (2022)
Ancestry Distribution
Score Development/Training
European: 100%
391,124 individuals (100%)
PGS Evaluation
European: 37.5%
African: 25%
East Asian: 12.5%
Greater Middle Eastern: 12.5%
South Asian: 12.5%
8 Sample Sets

Development Samples

Score Development/Training
Study Identifiers Sample Numbers Sample Ancestry Cohort(s) Phenotype Definitions & Methods Age of Study Participants Participant Follow-up Time Additional Ancestry Description Additional Sample/Cohort Information
— 391,124 individuals European UKB — — — UK (+ Ireland) —

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM012527 PSS009476|
European Ancestry|
19,837 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Use of sun/uv protection — — Partial Correlation (partial-r): 0.15 [0.1363, 0.1636] sex, age, birth date, deprivation index, 16 PCs —
PPM012528 PSS009250|
European Ancestry|
4,075 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Use of sun/uv protection — — Partial Correlation (partial-r): 0.0944 [0.0638, 0.1248] sex, age, birth date, deprivation index, 16 PCs —
PPM012529 PSS008804|
European Ancestry|
6,569 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Use of sun/uv protection — — Partial Correlation (partial-r): 0.1201 [0.0962, 0.1439] sex, age, birth date, deprivation index, 16 PCs —
PPM012530 PSS008578|
Greater Middle Eastern Ancestry|
1,095 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Use of sun/uv protection — — Partial Correlation (partial-r): 0.1117 [0.0522, 0.1703] sex, age, birth date, deprivation index, 16 PCs —
PPM012531 PSS008356|
South Asian Ancestry|
5,836 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Use of sun/uv protection — — Partial Correlation (partial-r): 0.051 [0.0253, 0.0766] sex, age, birth date, deprivation index, 16 PCs —
PPM012532 PSS008133|
East Asian Ancestry|
1,733 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Use of sun/uv protection — — Partial Correlation (partial-r): 0.0415 [-0.0059, 0.0887] sex, age, birth date, deprivation index, 16 PCs —
PPM012533 PSS007920|
African Ancestry|
2,375 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Use of sun/uv protection — — Partial Correlation (partial-r): 0.013 [-0.0274, 0.0534] sex, age, birth date, deprivation index, 16 PCs —
PPM012534 PSS009024|
African Ancestry|
3,660 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: Use of sun/uv protection — — Partial Correlation (partial-r): 0.0304 [-0.0021, 0.0628] sex, age, birth date, deprivation index, 16 PCs —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS009476 — — 19,837 individuals — European UK (+ Ireland) UKB —
PSS008804 — — 6,569 individuals — European Italy (South Europe) UKB —
PSS008356 — — 5,836 individuals — South Asian India (South Asia) UKB —
PSS008133 — — 1,733 individuals — East Asian China (East Asia) UKB —
PSS007920 — — 2,375 individuals — African American or Afro-Caribbean Carribean UKB —
PSS009250 — — 4,075 individuals — European Poland (NE Europe) UKB —
PSS009024 — — 3,660 individuals — African unspecified Nigeria (West Africa) UKB —
PSS008578 — — 1,095 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —