Polygenic Score (PGS) ID: PGS002435

Predicted Trait
Reported Trait Balding Type 1
Mapped Trait(s) balding measurement (EFO_0007825)
Released in PGS Catalog: June 9, 2022
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Score Details

Score Construction
PGS Name body_BALDING1.P+T.0.001
Development Method
Name Pruning and Thresholding (P+T)
Parameters p < 0.001
Variants
Original Genome Build GRCh37
Number of Variants 21,564
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000332
Citation (link to publication) Weissbrod O et al. Nat Genet (2022)
Ancestry Distribution
Source of Variant
Associations (GWAS)
European: 100%
155,100 individuals (100%)
PGS Evaluation
African: 25%
East Asian: 25%
European: 25%
South Asian: 25%
4 Sample Sets

Development Samples

Source of Variant Associations (GWAS)
Study Identifiers Sample Numbers Sample Ancestry Cohort(s)
— 155,100 individuals European UKB

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM013563 PSS009699|
African Ancestry|
2,687 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Balding Type 1 — — Incremental R2 (full model vs. covariates alone): 0.0011 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013612 PSS009700|
East Asian Ancestry|
331 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Balding Type 1 — — Incremental R2 (full model vs. covariates alone): 0.0059 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013661 PSS009701|
European Ancestry|
18,771 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Balding Type 1 — — Incremental R2 (full model vs. covariates alone): 0.0766 age, sex, age*sex, assessment center, genotyping array, 10 PCs —
PPM013710 PSS009702|
South Asian Ancestry|
4,185 individuals
 PGP000332 |
Weissbrod O et al. Nat Genet (2022)
 Reported Trait: Balding Type 1 — — Incremental R2 (full model vs. covariates alone): 0.0247 age, sex, age*sex, assessment center, genotyping array, 10 PCs —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS009700 — — 331 individuals — East Asian — UKB —
PSS009701 — — 18,771 individuals — European Non-British European UKB —
PSS009702 — — 4,185 individuals — South Asian — UKB —
PSS009699 — — 2,687 individuals — African unspecified — UKB —