Predicted Trait | |
Reported Trait | Drinking status |
Mapped Trait(s) | alcohol drinking (EFO_0004329) |
Additional Trait Information | Alcohol drinker status: Current; Binary |
Score Construction | |
PGS Name | ExPRSweb_Drinking_20117-2_PT_MGI_20211120 |
Development Method | |
Name | Pruning and Thresholding (P+T) |
Parameters | LD Clumping (using Plink to calculate LD, MAF >= 1%, r^2 <= 0.1) & P-value threshold <=... 6.31e-03Show more |
Variants | |
Original Genome Build | GRCh37 |
Number of Variants | 10,123 |
Effect Weight Type | beta |
PGS Source | |
PGS Catalog Publication (PGP) ID | PGP000393 |
Citation (link to publication) | Ma Y et al. Am J Hum Genet (2022) |
Study Identifiers
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Sample Numbers
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Sample Ancestry
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Cohort(s)
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360,726 individuals | European | UKB |
Study Identifiers
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Sample Numbers
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Sample Ancestry
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Cohort(s)
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Phenotype Definitions & Methods
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Age of Study Participants
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Participant Follow-up Time
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Additional Ancestry Description
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Additional Sample/Cohort Information
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— | [
| European | MGI | never/past/current alcohol use was recoded to never/ever responses.; Binary | — | — | — | — |
PGS Performance Metric ID (PPM) |
PGS Sample Set ID (PSS) |
Performance Source
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Trait
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PGS Effect Sizes (per SD change) |
Classification Metrics
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Other Metrics
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Covariates Included in the Model
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PGS Performance: Other Relevant Information |
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PPM015791 | PSS010002| European Ancestry| 22,425 individuals | PGP000393 | Ma Y et al. Am J Hum Genet (2022) | Reported Trait: Drinking Status | OR: 1.116 [1.085, 1.148] β: 0.11 (0.0144) | AUROC: 0.533 [0.525, 0.541] | — | SEX,AGE,Batch,PC1,PC2,PC3,PC4 | — |
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods
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Participant Follow-up Time
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Sample Numbers
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Age of Study Participants
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Sample Ancestry
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Additional Ancestry Description
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Cohort(s)
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Additional Sample/Cohort Information
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PSS010002 | never/past/current alcohol use was recoded to never/ever responses.; Binary | — | [
| — | European | — | MGI | — |