Trait: alcohol drinking

Experimental Factor Ontology (EFO) Information
Identifier EFO_0004329
Description Behaviors associated with the ingesting of alcoholic beverages, including social drinking.
Trait category
Biological process
Synonym alcohol consumption
Mapped terms 2 mapped terms
  • MESH:D000428
  • NCIt:C16273

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
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Polygenic Score ID & Name
PGS Publication ID (PGP)
Reported Trait
Mapped Trait(s) (Ontology)
Number of Variants
Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS001901
(portability-PLR_drink_alcohol)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Alcohol drinker statusalcohol drinking1,065
-
D
E
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001901/ScoringFiles/PGS001901.txt.gz
PGS002115
(portability-ldpred2_drink_alcohol)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Alcohol drinker statusalcohol drinking766,714
-
D
E
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002115/ScoringFiles/PGS002115.txt.gz
PGS002909
(ExPRSweb_Drinking_20117-2_LASSOSUM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Drinking statusalcohol drinking396,976
G
D
E
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002909/ScoringFiles/PGS002909.txt.gz
PGS002910
(ExPRSweb_Drinking_20117-2_PT_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Drinking statusalcohol drinking10,123
G
D
E
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002910/ScoringFiles/PGS002910.txt.gz
PGS002911
(ExPRSweb_Drinking_20117-2_PLINK_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Drinking statusalcohol drinking20,050
G
D
E
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002911/ScoringFiles/PGS002911.txt.gz
PGS002912
(ExPRSweb_Drinking_20117-2_DBSLMM_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Drinking statusalcohol drinking8,598,752
G
D
E
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002912/ScoringFiles/PGS002912.txt.gz
PGS002913
(ExPRSweb_Drinking_20117-2_PRSCS_MGI_20211120)
PGP000393 |
Ma Y et al. Am J Hum Genet (2022)
Drinking statusalcohol drinking1,113,832
G
D
E
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002913/ScoringFiles/PGS002913.txt.gz
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Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

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PGS Performance
Metric ID (PPM)
Evaluated Score
PGS Sample Set ID
(PSS)
Performance Source
Trait
PGS Effect Sizes
(per SD change)
Classification Metrics
Other Metrics
Covariates Included in the Model
PGS Performance:
Other Relevant Information
PPM010091PGS001901
(portability-PLR_drink_alcohol)
PSS009398|
European Ancestry|
19,294 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alcohol drinker status——Partial Correlation (partial-r): 0.0209 [0.0068, 0.035]sex, age, birth date, deprivation index, 16 PCs—
PPM010092PGS001901
(portability-PLR_drink_alcohol)
PSS009172|
European Ancestry|
3,938 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alcohol drinker status——Partial Correlation (partial-r): 0.0195 [-0.0118, 0.0508]sex, age, birth date, deprivation index, 16 PCs—
PPM010093PGS001901
(portability-PLR_drink_alcohol)
PSS008726|
European Ancestry|
6,413 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alcohol drinker status——Partial Correlation (partial-r): 0.0217 [-0.0028, 0.0462]sex, age, birth date, deprivation index, 16 PCs—
PPM010094PGS001901
(portability-PLR_drink_alcohol)
PSS008500|
Greater Middle Eastern Ancestry|
1,101 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alcohol drinker status——Partial Correlation (partial-r): 0.0069 [-0.0527, 0.0665]sex, age, birth date, deprivation index, 16 PCs—
PPM010095PGS001901
(portability-PLR_drink_alcohol)
PSS008278|
South Asian Ancestry|
5,830 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alcohol drinker status——Partial Correlation (partial-r): 0.0024 [-0.0233, 0.0281]sex, age, birth date, deprivation index, 16 PCs—
PPM010096PGS001901
(portability-PLR_drink_alcohol)
PSS008055|
East Asian Ancestry|
1,726 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alcohol drinker status——Partial Correlation (partial-r): 0.0204 [-0.0271, 0.0678]sex, age, birth date, deprivation index, 16 PCs—
PPM010097PGS001901
(portability-PLR_drink_alcohol)
PSS007842|
African Ancestry|
2,357 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alcohol drinker status——Partial Correlation (partial-r): 0.0195 [-0.021, 0.06]sex, age, birth date, deprivation index, 16 PCs—
PPM010098PGS001901
(portability-PLR_drink_alcohol)
PSS008946|
African Ancestry|
3,609 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alcohol drinker status——Partial Correlation (partial-r): 0.0279 [-0.0048, 0.0606]sex, age, birth date, deprivation index, 16 PCs—
PPM011775PGS002115
(portability-ldpred2_drink_alcohol)
PSS009398|
European Ancestry|
19,294 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alcohol drinker status——Partial Correlation (partial-r): 0.0284 [0.0143, 0.0425]sex, age, birth date, deprivation index, 16 PCs—
PPM011776PGS002115
(portability-ldpred2_drink_alcohol)
PSS009172|
European Ancestry|
3,938 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alcohol drinker status——Partial Correlation (partial-r): 0.0691 [0.0379, 0.1002]sex, age, birth date, deprivation index, 16 PCs—
PPM011777PGS002115
(portability-ldpred2_drink_alcohol)
PSS008726|
European Ancestry|
6,413 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alcohol drinker status——Partial Correlation (partial-r): 0.0566 [0.0321, 0.081]sex, age, birth date, deprivation index, 16 PCs—
PPM011778PGS002115
(portability-ldpred2_drink_alcohol)
PSS008500|
Greater Middle Eastern Ancestry|
1,101 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alcohol drinker status——Partial Correlation (partial-r): 0.0437 [-0.016, 0.1031]sex, age, birth date, deprivation index, 16 PCs—
PPM011779PGS002115
(portability-ldpred2_drink_alcohol)
PSS008278|
South Asian Ancestry|
5,830 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alcohol drinker status——Partial Correlation (partial-r): 0.0014 [-0.0243, 0.0271]sex, age, birth date, deprivation index, 16 PCs—
PPM011780PGS002115
(portability-ldpred2_drink_alcohol)
PSS008055|
East Asian Ancestry|
1,726 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alcohol drinker status——Partial Correlation (partial-r): 0.02 [-0.0275, 0.0674]sex, age, birth date, deprivation index, 16 PCs—
PPM011781PGS002115
(portability-ldpred2_drink_alcohol)
PSS007842|
African Ancestry|
2,357 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Alcohol drinker status——Partial Correlation (partial-r): 0.0094 [-0.0311, 0.0499]sex, age, birth date, deprivation index, 16 PCs—
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Evaluated Samples

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PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods
Participant Follow-up Time
Sample Numbers
Age of Study Participants
Sample Ancestry
Additional Ancestry Description
Cohort(s)
Additional Sample/Cohort Information
PSS007842——2,357 individuals—African American or Afro-CaribbeanCarribeanUKB—
PSS008055——1,726 individuals—East AsianChina (East Asia)UKB—
PSS008278——5,830 individuals—South AsianIndia (South Asia)UKB—
PSS008500——1,101 individuals—Greater Middle Eastern (Middle Eastern, North African or Persian)Iran (Middle East)UKB—
PSS008726——6,413 individuals—EuropeanItaly (South Europe)UKB—
PSS008946——3,609 individuals—African unspecifiedNigeria (West Africa)UKB—
PSS009172——3,938 individuals—EuropeanPoland (NE Europe)UKB—
PSS009398——19,294 individuals—EuropeanUK (+ Ireland)UKB—
PSS010002never/past/current alcohol use was recoded to never/ever responses.; Binary—
[
  • 15,343 cases
  • , 7,082 controls
]
—European—MGI—
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