Polygenic Score (PGS) ID: PGS003336

Predicted Trait
Reported Trait Fasting plasma glucose
Mapped Trait(s) fasting blood glucose measurement (EFO_0004465)
Released in PGS Catalog: Dec. 20, 2022
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Score Details

Score Construction
PGS Name CVGRS_FPG
Development Method
Name Genome-wide significant SNPs
Parameters NR
Variants
Original Genome Build NR
Number of Variants 56
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000405
Citation (link to publication) Kim YJ et al. Nat Commun (2022)
Ancestry Distribution
Source of Variant
Associations (GWAS)
East Asian: 100%
288,127 individuals (100%)
PGS Evaluation
East Asian: 100%
1 Sample Sets

Development Samples

Source of Variant Associations (GWAS)
Study Identifiers Sample Numbers Sample Ancestry Cohort(s)
— 288,127 individuals East Asian
(Korean, Japanese)		 Ansan, Ansung, BBJ, CAVAS, HEXA

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM016175 PSS010055|
East Asian Ancestry|
22,608 individuals
 PGP000405 |
Kim YJ et al. Nat Commun (2022)
 Reported Trait: Fasting plasma glucose β: 0.20444 — — — —
PPM016192 PSS010055|
East Asian Ancestry|
22,608 individuals
 PGP000405 |
Kim YJ et al. Nat Commun (2022)
 Reported Trait: Type 2 diabetes OR: 1.46435 — — — —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS010055 — — 22,608 individuals — East Asian — KBA, KoGES —