Polygenic Score (PGS) ID: PGS003813

Predicted Trait
Reported Trait Log triglycerides
Mapped Trait(s) triglyceride measurement (EFO_0004530)
Released in PGS Catalog: Sept. 1, 2023
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Terms and Licenses
PGS obtained from the Catalog should be cited appropriately, and used in accordance with any licensing restrictions set by the authors. See EBI Terms of Use (https://www.ebi.ac.uk/about/terms-of-use/) for additional details.

Score Details

Score Construction
PGS Name logTG_SAS_CT
Development Method
Name Clumping and Thresholding (C+T)
Parameters clumping window size=500kb, clumping r2=0.1, p-value threshold = c(5E-08,5E-07,...,0.5,1)
Variants
Original Genome Build GRCh37
Number of Variants 40
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000489
Citation (link to publication) Zhang H et al. Nat Genet (2023)
Ancestry Distribution
Source of Variant
Associations (GWAS)
South Asian: 100%
34,023 individuals (100%)
Score Development/Training
South Asian: 100%
5,145 individuals (100%)
PGS Evaluation
South Asian: 100%
1 Sample Sets

Development Samples

Source of Variant Associations (GWAS)
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Study Identifiers
Sample Numbers
Sample Ancestry
Cohort(s)
Europe PMC: 34887591
34,023 individualsSouth AsianNR
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Score Development/Training
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Study Identifiers
Sample Numbers
Sample Ancestry
Cohort(s)
Phenotype Definitions & Methods
Age of Study Participants
Participant Follow-up Time
Additional Ancestry Description
Additional Sample/Cohort Information
—5,145 individuals,
53.0 % Male samples
South AsianUKB—Mean = 53.37 years
Sd = 8.43 years		———
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Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

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PGS Performance
Metric ID (PPM)
PGS Sample Set ID
(PSS)
Performance Source
Trait
PGS Effect Sizes
(per SD change)
Classification Metrics
Other Metrics
Covariates Included in the Model
PGS Performance:
Other Relevant Information
PPM018620PSS011054|
South Asian Ancestry|
5,143 individuals
PGP000489 |
Zhang H et al. Nat Genet (2023)
Reported Trait: Log triglycerides——R²: 0.06482——
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Evaluated Samples

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PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods
Participant Follow-up Time
Sample Numbers
Age of Study Participants
Sample Ancestry
Additional Ancestry Description
Cohort(s)
Additional Sample/Cohort Information
PSS011054——5,143 individuals,
53.0 % Male samples
Mean = 53.37 years
Sd = 8.43 years		South Asian—UKB—
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