Polygenic Score (PGS) ID: PGS004531

Predicted Trait
Reported Trait I48 (Atrial fibrillation and flutter)
Mapped Trait(s) atrial fibrillation (EFO_0000275)
Released in PGS Catalog: March 18, 2024
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Terms and Licenses
PGS obtained from the Catalog should be cited appropriately, and used in accordance with any licensing restrictions set by the authors. See EBI Terms of Use (https://www.ebi.ac.uk/about/terms-of-use/) for additional details.

Score Details

Score Construction
PGS Name meta.I48.score
Development Method
Name RFDiseasemetaPRS
Parameters Elasticnet regression (Disease PRS + risk factor PRSs)
Variants
Original Genome Build GRCh37
Number of Variants 1,059,939
Effect Weight Type beta
PGS Source
PGS Catalog Publication (PGP) ID PGP000561
Citation (link to publication) Jung H et al. Commun Biol (2024)
Ancestry Distribution
Score Development/Training
European: 100%
174,489 individuals (100%)
PGS Evaluation
European: 100%
1 Sample Sets

Development Samples

Score Development/Training
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Study Identifiers
Sample Numbers
Sample Ancestry
Cohort(s)
Phenotype Definitions & Methods
Age of Study Participants
Participant Follow-up Time
Additional Ancestry Description
Additional Sample/Cohort Information
—174,489 individualsEuropeanUKB—————
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Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

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PGS Performance
Metric ID (PPM)
PGS Sample Set ID
(PSS)
Performance Source
Trait
PGS Effect Sizes
(per SD change)
Classification Metrics
Other Metrics
Covariates Included in the Model
PGS Performance:
Other Relevant Information
PPM020646PSS011364|
European Ancestry|
56,192 individuals
PGP000561 |
Jung H et al. Commun Biol (2024)
Reported Trait: I48 (Atrial fibrillation and flutter)OR: 1.27953————
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Evaluated Samples

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PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods
Participant Follow-up Time
Sample Numbers
Age of Study Participants
Sample Ancestry
Additional Ancestry Description
Cohort(s)
Additional Sample/Cohort Information
PSS011364——56,192 individuals—European—UKB—
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