Predicted Trait | |
Reported Trait | Hypertension |
Mapped Trait(s) | hypertension (EFO_0000537) |
Score Construction | |
PGS Name | Hypertension (CT-SLEB; EAS+EUR) |
Development Method | |
Name | CT-SLEB |
Parameters | SNP r2 threshold: 0.05, window size (kb) 2000, P-value threshold: 5.00E-06 |
Variants | |
Original Genome Build | hg19 |
Number of Variants | 492,555 |
Effect Weight Type | beta |
PGS Source | |
PGS Catalog Publication (PGP) ID | PGP000704 |
Citation (link to publication) | Jung HU et al. Commun Biol (2025) |
Ancestry Distribution | |
Source of Variant Associations (GWAS) | European: 83.9% East Asian: 16.1% 903,106 individuals (100%) |
PGS Evaluation | East Asian: 100% 1 Sample Sets |
Study Identifiers | Sample Numbers | Sample Ancestry | Cohort(s) |
---|---|---|---|
GWAS Catalog: GCST90018752 Europe PMC: 34594039 |
145,505 individuals | East Asian | BBJ |
GWAS Catalog: GCST006624 Europe PMC: 30224653 |
757,601 individuals | European | NR |
PGS Performance Metric ID (PPM) |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
---|---|---|---|---|---|---|---|---|
PPM022373 | PSS011921| East Asian Ancestry| 37,185 individuals |
PGP000704 | Jung HU et al. Commun Biol (2025) |
Reported Trait: Hypertension | β: 2.03809 | — | — | age, sex | — |
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
---|---|---|---|---|---|---|---|---|
PSS011921 | — | — | [
|
— | East Asian (Korean) |
— | HEXA | — |