Predicted Trait | |
Reported Trait | Obesity |
Mapped Trait(s) | obesity (EFO_0001073) |
Score Construction | |
PGS Name | Obesity (CT-SLEB; EAS+EUR) |
Development Method | |
Name | CT-SLEB |
Parameters | SNP r2 threshold: 0.5, window size (kb) 200, P-value threshold: 5.00E-04 |
Variants | |
Original Genome Build | hg19 |
Number of Variants | 443,124 |
Effect Weight Type | beta |
PGS Source | |
PGS Catalog Publication (PGP) ID | PGP000704 |
Citation (link to publication) | Jung HU et al. Commun Biol (2025) |
Ancestry Distribution | |
Source of Variant Associations (GWAS) | European: 80.6% East Asian: 19.4% 845,110 individuals (100%) |
PGS Evaluation | East Asian: 100% 1 Sample Sets |
Study Identifiers | Sample Numbers | Sample Ancestry | Cohort(s) |
---|---|---|---|
GWAS Catalog: GCST90018727 Europe PMC: 34594039 |
163,835 individuals | East Asian | BBJ |
Europe PMC: 30124842 |
681,275 individuals | European | NR |
PGS Performance Metric ID (PPM) |
PGS Sample Set ID (PSS) |
Performance Source | Trait |
PGS Effect Sizes (per SD change) |
Classification Metrics | Other Metrics | Covariates Included in the Model |
PGS Performance: Other Relevant Information |
---|---|---|---|---|---|---|---|---|
PPM022374 | PSS011928| East Asian Ancestry| 58,688 individuals |
PGP000704 | Jung HU et al. Commun Biol (2025) |
Reported Trait: Obesity | β: 1.76188 | — | — | age, sex | — |
PGS Sample Set ID (PSS) |
Phenotype Definitions and Methods | Participant Follow-up Time | Sample Numbers | Age of Study Participants | Sample Ancestry | Additional Ancestry Description | Cohort(s) | Additional Sample/Cohort Information |
---|---|---|---|---|---|---|---|---|
PSS011928 | — | — | [
|
— | East Asian (Korean) |
— | HEXA | — |