Trait: birth weight

Experimental Factor Ontology (EFO) Information
Identifier EFO_0004344
Description The mass or quantity of heaviness of an individual at BIRTH. It is expressed by units of pounds...  or kilograms.Show more
Trait category
Body measurement
Synonym birthweight
Mapped terms 3 mapped terms
  • MeSH:D001724
  • NCIt:C76325
  • SNOMEDCT:364589006

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Loading, please wait
Polygenic Score ID & Name
PGS Publication ID (PGP)
Reported Trait
Mapped Trait(s) (Ontology)
Number of Variants
Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS001226
(GBE_INI20022)
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Birth weightbirth weight6,278
-
D
E
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001226/ScoringFiles/PGS001226.txt.gz
PGS001892
(portability-PLR_birth_weight)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Birth weightbirth weight35,060
-
D
E
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001892/ScoringFiles/PGS001892.txt.gz
PGS002105
(portability-ldpred2_birth_weight)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Birth weightbirth weight827,714
-
D
E
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002105/ScoringFiles/PGS002105.txt.gz
PGS003494
(cont-decay-birth_weight)
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Birth weightbirth weight979,739
-
D
E
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003494/ScoringFiles/PGS003494.txt.gz
PGS004426
(X20022.score)
PGP000561 |
Jung H et al. Commun Biol (2024)
Birth weightbirth weight1,059,939
-
D
E
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS004426/ScoringFiles/PGS004426.txt.gz
Showing 1 to 5 of 5 rows

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

Loading, please wait
PGS Performance
Metric ID (PPM)
Evaluated Score
PGS Sample Set ID
(PSS)
Performance Source
Trait
PGS Effect Sizes
(per SD change)
Classification Metrics
Other Metrics
Covariates Included in the Model
PGS Performance:
Other Relevant Information
PPM008644PGS001226
(GBE_INI20022)
PSS004896|
African Ancestry|
1,708 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Birth weight: 0.04004 [0.0307, 0.04937]
Incremental R2 (full-covars): 0.00368
PGS R2 (no covariates): 0.00672 [0.00276, 0.01067]
age, sex, UKB array type, Genotype PCs
PPM008645PGS001226
(GBE_INI20022)
PSS004897|
East Asian Ancestry|
609 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Birth weight: 0.04464 [0.02551, 0.06377]
Incremental R2 (full-covars): 0.01768
PGS R2 (no covariates): 0.02148 [0.00789, 0.03508]
age, sex, UKB array type, Genotype PCs
PPM008646PGS001226
(GBE_INI20022)
PSS004898|
European Ancestry|
12,908 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Birth weight: 0.06034 [0.05461, 0.06608]
Incremental R2 (full-covars): 0.02543
PGS R2 (no covariates): 0.02732 [0.02333, 0.03131]
age, sex, UKB array type, Genotype PCs
PPM008647PGS001226
(GBE_INI20022)
PSS004899|
South Asian Ancestry|
1,908 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Birth weight: 0.04888 [0.03957, 0.05819]
Incremental R2 (full-covars): 0.00482
PGS R2 (no covariates): 0.00796 [0.00404, 0.01188]
age, sex, UKB array type, Genotype PCs
PPM008648PGS001226
(GBE_INI20022)
PSS004900|
European Ancestry|
39,107 individuals
PGP000244 |
Tanigawa Y et al. PLoS Genet (2022)
Reported Trait: Birth weight: 0.05162 [0.04837, 0.05488]
Incremental R2 (full-covars): 0.02688
PGS R2 (no covariates): 0.02741 [0.02498, 0.02984]
age, sex, UKB array type, Genotype PCs
PPM010020PGS001892
(portability-PLR_birth_weight)
PSS009388|
European Ancestry|
11,255 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Birth weightPartial Correlation (partial-r): 0.1913 [0.1734, 0.209]sex, age, birth date, deprivation index, 16 PCs
PPM010021PGS001892
(portability-PLR_birth_weight)
PSS009162|
European Ancestry|
2,139 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Birth weightPartial Correlation (partial-r): 0.1447 [0.1027, 0.1861]sex, age, birth date, deprivation index, 16 PCs
PPM010022PGS001892
(portability-PLR_birth_weight)
PSS008716|
European Ancestry|
3,422 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Birth weightPartial Correlation (partial-r): 0.1639 [0.131, 0.1964]sex, age, birth date, deprivation index, 16 PCs
PPM010023PGS001892
(portability-PLR_birth_weight)
PSS008490|
Greater Middle Eastern Ancestry|
303 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Birth weightPartial Correlation (partial-r): 0.1653 [0.0496, 0.2766]sex, age, birth date, deprivation index, 16 PCs
PPM010024PGS001892
(portability-PLR_birth_weight)
PSS008268|
South Asian Ancestry|
1,505 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Birth weightPartial Correlation (partial-r): 0.1064 [0.0559, 0.1565]sex, age, birth date, deprivation index, 16 PCs
PPM010025PGS001892
(portability-PLR_birth_weight)
PSS008046|
East Asian Ancestry|
714 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Birth weightPartial Correlation (partial-r): 0.1533 [0.0798, 0.2251]sex, age, birth date, deprivation index, 16 PCs
PPM010026PGS001892
(portability-PLR_birth_weight)
PSS007832|
African Ancestry|
840 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Birth weightPartial Correlation (partial-r): 0.0983 [0.03, 0.1656]sex, age, birth date, deprivation index, 16 PCs
PPM010027PGS001892
(portability-PLR_birth_weight)
PSS008936|
African Ancestry|
791 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Birth weightPartial Correlation (partial-r): 0.1149 [0.0447, 0.1841]sex, age, birth date, deprivation index, 16 PCs
PPM011696PGS002105
(portability-ldpred2_birth_weight)
PSS009388|
European Ancestry|
11,255 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Birth weightPartial Correlation (partial-r): 0.2001 [0.1823, 0.2178]sex, age, birth date, deprivation index, 16 PCs
PPM011697PGS002105
(portability-ldpred2_birth_weight)
PSS009162|
European Ancestry|
2,139 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Birth weightPartial Correlation (partial-r): 0.1536 [0.1118, 0.1949]sex, age, birth date, deprivation index, 16 PCs
Showing 1 to 15 of 31 rows
rows per page

Evaluated Samples

Loading, please wait
PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods
Participant Follow-up Time
Sample Numbers
Age of Study Participants
Sample Ancestry
Additional Ancestry Description
Cohort(s)
Additional Sample/Cohort Information
PSS0048961,708 individualsAfrican unspecifiedUKB
PSS004897609 individualsEast AsianUKB
PSS00489812,908 individualsEuropeannon-white British ancestryUKB
PSS0048991,908 individualsSouth AsianUKB
PSS00490039,107 individualsEuropeanwhite British ancestryUKBTesting cohort (heldout set)
PSS007832840 individualsAfrican American or Afro-CaribbeanCarribeanUKB
PSS008046714 individualsEast AsianChina (East Asia)UKB
PSS0082681,505 individualsSouth AsianIndia (South Asia)UKB
PSS008490303 individualsGreater Middle Eastern (Middle Eastern, North African or Persian)Iran (Middle East)UKB
PSS0087163,422 individualsEuropeanItaly (South Europe)UKB
PSS008936791 individualsAfrican unspecifiedNigeria (West Africa)UKB
PSS0091622,139 individualsEuropeanPoland (NE Europe)UKB
PSS00938811,255 individualsEuropeanUK (+ Ireland)UKB
PSS0102311,260 individuals,
39.0 % Male samples
Mean = 57.0 years
Sd = 7.2 years
EuropeanAshkenaziUKB
PSS010315838 individuals,
34.0 % Male samples
Mean = 50.5 years
Sd = 7.6 years
African American or Afro-CaribbeanCaribbeanUKB
Showing 1 to 15 of 23 rows
rows per page