Trait: RR interval

Experimental Factor Ontology (EFO) Information
Identifier EFO_0004831
Description A RR interval is an electrocardiography measurement - R wave to R wave interval (RR interval) and is the inverse of the heart rate.
Trait category
Cardiovascular measurement

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS001907
(portability-PLR_ECG_RR_interval)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 RR interval RR interval 1,964
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS001907/ScoringFiles/PGS001907.txt.gz
PGS002121
(portability-ldpred2_ECG_RR_interval)
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 RR interval RR interval 616,710
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002121/ScoringFiles/PGS002121.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM010139 PGS001907
(portability-PLR_ECG_RR_interval)
 PSS009368|
European Ancestry|
1,042 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: RR interval — — Partial Correlation (partial-r): 0.065 [0.0037, 0.1258] sex, age, birth date, deprivation index, 16 PCs —
PPM010140 PGS001907
(portability-PLR_ECG_RR_interval)
 PSS009142|
European Ancestry|
193 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: RR interval — — Partial Correlation (partial-r): 0.0882 [-0.0618, 0.2343] sex, age, birth date, deprivation index, 16 PCs —
PPM010141 PGS001907
(portability-PLR_ECG_RR_interval)
 PSS008696|
European Ancestry|
226 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: RR interval — — Partial Correlation (partial-r): 0.1096 [-0.0276, 0.2426] sex, age, birth date, deprivation index, 16 PCs —
PPM010142 PGS001907
(portability-PLR_ECG_RR_interval)
 PSS008470|
Greater Middle Eastern Ancestry|
26 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: RR interval — — Partial Correlation (partial-r): -0.3743 [-0.9096, 0.628] sex, age, birth date, deprivation index, 16 PCs —
PPM010143 PGS001907
(portability-PLR_ECG_RR_interval)
 PSS008250|
South Asian Ancestry|
166 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: RR interval — — Partial Correlation (partial-r): 0.0596 [-0.1039, 0.2199] sex, age, birth date, deprivation index, 16 PCs —
PPM010144 PGS001907
(portability-PLR_ECG_RR_interval)
 PSS008028|
East Asian Ancestry|
73 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: RR interval — — Partial Correlation (partial-r): 0.1051 [-0.1701, 0.365] sex, age, birth date, deprivation index, 16 PCs —
PPM010146 PGS001907
(portability-PLR_ECG_RR_interval)
 PSS008918|
African Ancestry|
61 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: RR interval — — Partial Correlation (partial-r): 0.0322 [-0.2782, 0.3365] sex, age, birth date, deprivation index, 16 PCs —
PPM010145 PGS001907
(portability-PLR_ECG_RR_interval)
 PSS007814|
African Ancestry|
49 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: RR interval — — Partial Correlation (partial-r): -0.1946 [-0.5237, 0.1851] sex, age, birth date, deprivation index, 16 PCs —
PPM011824 PGS002121
(portability-ldpred2_ECG_RR_interval)
 PSS009142|
European Ancestry|
193 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: RR interval — — Partial Correlation (partial-r): 0.2615 [0.1169, 0.3953] sex, age, birth date, deprivation index, 16 PCs —
PPM011823 PGS002121
(portability-ldpred2_ECG_RR_interval)
 PSS009368|
European Ancestry|
1,042 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: RR interval — — Partial Correlation (partial-r): 0.1001 [0.039, 0.1604] sex, age, birth date, deprivation index, 16 PCs —
PPM011825 PGS002121
(portability-ldpred2_ECG_RR_interval)
 PSS008696|
European Ancestry|
226 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: RR interval — — Partial Correlation (partial-r): 0.115 [-0.022, 0.2478] sex, age, birth date, deprivation index, 16 PCs —
PPM011826 PGS002121
(portability-ldpred2_ECG_RR_interval)
 PSS008470|
Greater Middle Eastern Ancestry|
26 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: RR interval — — Partial Correlation (partial-r): 0.2994 [-0.6766, 0.8938] sex, age, birth date, deprivation index, 16 PCs —
PPM011827 PGS002121
(portability-ldpred2_ECG_RR_interval)
 PSS008250|
South Asian Ancestry|
166 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: RR interval — — Partial Correlation (partial-r): 0.0599 [-0.1036, 0.2202] sex, age, birth date, deprivation index, 16 PCs —
PPM011828 PGS002121
(portability-ldpred2_ECG_RR_interval)
 PSS008028|
East Asian Ancestry|
73 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: RR interval — — Partial Correlation (partial-r): 0.1681 [-0.107, 0.4194] sex, age, birth date, deprivation index, 16 PCs —
PPM011829 PGS002121
(portability-ldpred2_ECG_RR_interval)
 PSS007814|
African Ancestry|
49 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: RR interval — — Partial Correlation (partial-r): 0.0409 [-0.3305, 0.4014] sex, age, birth date, deprivation index, 16 PCs —
PPM011830 PGS002121
(portability-ldpred2_ECG_RR_interval)
 PSS008918|
African Ancestry|
61 individuals
 PGP000263 |
Privé F et al. Am J Hum Genet (2022)
 Reported Trait: RR interval — — Partial Correlation (partial-r): -0.0491 [-0.3514, 0.2625] sex, age, birth date, deprivation index, 16 PCs —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS007814 — — 49 individuals — African American or Afro-Caribbean Carribean UKB —
PSS009142 — — 193 individuals — European Poland (NE Europe) UKB —
PSS008470 — — 26 individuals — Greater Middle Eastern (Middle Eastern, North African or Persian) Iran (Middle East) UKB —
PSS009368 — — 1,042 individuals — European UK (+ Ireland) UKB —
PSS008696 — — 226 individuals — European Italy (South Europe) UKB —
PSS008250 — — 166 individuals — South Asian India (South Asia) UKB —
PSS008918 — — 61 individuals — African unspecified Nigeria (West Africa) UKB —
PSS008028 — — 73 individuals — East Asian China (East Asia) UKB —