Trait: eye inflammation

Experimental Factor Ontology (EFO) Information
Identifier EFO_0005752
Description an inflammation in the eye(s)
Trait category
Other trait
Mapped term MedDRA:10015943

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
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Polygenic Score ID & Name
PGS Publication ID (PGP)
Reported Trait
Mapped Trait(s) (Ontology)
Number of Variants
Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS002045
(portability-ldpred2_371)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Inflammation of the eyeeye disease,
eye inflammation		527,030
-
D
E
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002045/ScoringFiles/PGS002045.txt.gz
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Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

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PGS Performance
Metric ID (PPM)
Evaluated Score
PGS Sample Set ID
(PSS)
Performance Source
Trait
PGS Effect Sizes
(per SD change)
Classification Metrics
Other Metrics
Covariates Included in the Model
PGS Performance:
Other Relevant Information
PPM011224PGS002045
(portability-ldpred2_371)
PSS009308|
European Ancestry|
19,618 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Inflammation of the eye——Partial Correlation (partial-r): 0.0162 [0.0022, 0.0302]sex, age, birth date, deprivation index, 16 PCs—
PPM011225PGS002045
(portability-ldpred2_371)
PSS009082|
European Ancestry|
4,069 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Inflammation of the eye——Partial Correlation (partial-r): -0.007 [-0.0378, 0.0238]sex, age, birth date, deprivation index, 16 PCs—
PPM011226PGS002045
(portability-ldpred2_371)
PSS008636|
European Ancestry|
6,561 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Inflammation of the eye——Partial Correlation (partial-r): 0.0309 [0.0067, 0.0551]sex, age, birth date, deprivation index, 16 PCs—
PPM011227PGS002045
(portability-ldpred2_371)
PSS008410|
Greater Middle Eastern Ancestry|
1,183 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Inflammation of the eye——Partial Correlation (partial-r): 0.0226 [-0.0349, 0.08]sex, age, birth date, deprivation index, 16 PCs—
PPM011228PGS002045
(portability-ldpred2_371)
PSS008190|
South Asian Ancestry|
6,184 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Inflammation of the eye——Partial Correlation (partial-r): 0.01 [-0.015, 0.0349]sex, age, birth date, deprivation index, 16 PCs—
PPM011229PGS002045
(portability-ldpred2_371)
PSS007973|
East Asian Ancestry|
1,779 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Inflammation of the eye——Partial Correlation (partial-r): -0.0042 [-0.0509, 0.0426]sex, age, birth date, deprivation index, 16 PCs—
PPM011230PGS002045
(portability-ldpred2_371)
PSS007755|
African Ancestry|
2,428 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Inflammation of the eye——Partial Correlation (partial-r): -0.0067 [-0.0466, 0.0333]sex, age, birth date, deprivation index, 16 PCs—
PPM011231PGS002045
(portability-ldpred2_371)
PSS008860|
African Ancestry|
3,820 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Inflammation of the eye——Partial Correlation (partial-r): -0.008 [-0.0397, 0.0238]sex, age, birth date, deprivation index, 16 PCs—
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Evaluated Samples

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PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods
Participant Follow-up Time
Sample Numbers
Age of Study Participants
Sample Ancestry
Additional Ancestry Description
Cohort(s)
Additional Sample/Cohort Information
PSS007755——2,428 individuals—African American or Afro-CaribbeanCarribeanUKB—
PSS007973——1,779 individuals—East AsianChina (East Asia)UKB—
PSS008190——6,184 individuals—South AsianIndia (South Asia)UKB—
PSS008410——1,183 individuals—Greater Middle Eastern (Middle Eastern, North African or Persian)Iran (Middle East)UKB—
PSS008636——6,561 individuals—EuropeanItaly (South Europe)UKB—
PSS008860——3,820 individuals—African unspecifiedNigeria (West Africa)UKB—
PSS009082——4,069 individuals—EuropeanPoland (NE Europe)UKB—
PSS009308——19,618 individuals—EuropeanUK (+ Ireland)UKB—
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