Trait: depressive episode measurement

Experimental Factor Ontology (EFO) Information
Identifier EFO_0007704
Description quantification of some aspect, eg frequency or severity, of depressive episodes in patients with men... tal or behavioural disorders such as bipolar disorder or clinical depressionShow more
Trait category
Other measurement

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
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Polygenic Score ID & Name
PGS Publication ID (PGP)
Reported Trait
Mapped Trait(s) (Ontology)
Number of Variants
Ancestry distribution
GWAS
Dev
Eval
Scoring File (FTP Link)
PGS002113
(portability-ldpred2_depression_stress_trauma)
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Depression possibly related to stressful or traumatic eventdepressive episode measurement,
trauma exposure measurement
545,334
-
D
E
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS002113/ScoringFiles/PGS002113.txt.gz
PGS003497
(cont-decay-depressed_for_1w)
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Ever depressed for a whole weekdepressive episode measurement979,739
-
D
E
https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003497/ScoringFiles/PGS003497.txt.gz
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Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

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PGS Performance
Metric ID (PPM)
Evaluated Score
PGS Sample Set ID
(PSS)
Performance Source
Trait
PGS Effect Sizes
(per SD change)
Classification Metrics
Other Metrics
Covariates Included in the Model
PGS Performance:
Other Relevant Information
PPM011759PGS002113
(portability-ldpred2_depression_stress_trauma)
PSS009396|
European Ancestry|
3,597 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Depression possibly related to stressful or traumatic eventPartial Correlation (partial-r): 0.0378 [0.005, 0.0705]sex, age, birth date, deprivation index, 16 PCs
PPM011760PGS002113
(portability-ldpred2_depression_stress_trauma)
PSS009170|
European Ancestry|
741 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Depression possibly related to stressful or traumatic eventPartial Correlation (partial-r): 0.0272 [-0.0459, 0.1001]sex, age, birth date, deprivation index, 16 PCs
PPM011761PGS002113
(portability-ldpred2_depression_stress_trauma)
PSS008724|
European Ancestry|
1,364 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Depression possibly related to stressful or traumatic eventPartial Correlation (partial-r): 0.0391 [-0.0144, 0.0924]sex, age, birth date, deprivation index, 16 PCs
PPM011762PGS002113
(portability-ldpred2_depression_stress_trauma)
PSS008498|
Greater Middle Eastern Ancestry|
100 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Depression possibly related to stressful or traumatic eventPartial Correlation (partial-r): -0.0739 [-0.2889, 0.1482]sex, age, birth date, deprivation index, 16 PCs
PPM011763PGS002113
(portability-ldpred2_depression_stress_trauma)
PSS008276|
South Asian Ancestry|
425 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Depression possibly related to stressful or traumatic eventPartial Correlation (partial-r): 0.1438 [0.0471, 0.238]sex, age, birth date, deprivation index, 16 PCs
PPM011764PGS002113
(portability-ldpred2_depression_stress_trauma)
PSS008053|
East Asian Ancestry|
215 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Depression possibly related to stressful or traumatic eventPartial Correlation (partial-r): 0.0141 [-0.1267, 0.1543]sex, age, birth date, deprivation index, 16 PCs
PPM011765PGS002113
(portability-ldpred2_depression_stress_trauma)
PSS007840|
African Ancestry|
215 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Depression possibly related to stressful or traumatic eventPartial Correlation (partial-r): -0.0269 [-0.1668, 0.114]sex, age, birth date, deprivation index, 16 PCs
PPM011766PGS002113
(portability-ldpred2_depression_stress_trauma)
PSS008944|
African Ancestry|
214 individuals
PGP000263 |
Privé F et al. Am J Hum Genet (2022)
Reported Trait: Depression possibly related to stressful or traumatic eventPartial Correlation (partial-r): -0.0334 [-0.1734, 0.108]sex, age, birth date, deprivation index, 16 PCs
PPM017425PGS003497
(cont-decay-depressed_for_1w)
PSS010936|
European Ancestry|
6,610 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Ever depressed for a whole weekpartial-R2: 0.01sex, age, deprivation index, PC1-16
PPM017509PGS003497
(cont-decay-depressed_for_1w)
PSS010852|
European Ancestry|
1,520 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Ever depressed for a whole weekpartial-R2: 0.01sex, age, deprivation index, PC1-16
PPM017593PGS003497
(cont-decay-depressed_for_1w)
PSS010684|
European Ancestry|
2,449 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Ever depressed for a whole weekpartial-R2: 0.01sex, age, deprivation index, PC1-16
PPM017677PGS003497
(cont-decay-depressed_for_1w)
PSS010600|
Greater Middle Eastern Ancestry|
505 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Ever depressed for a whole weekpartial-R2: 0.0sex, age, deprivation index, PC1-16
PPM017761PGS003497
(cont-decay-depressed_for_1w)
PSS010264|
European Ancestry|
593 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Ever depressed for a whole weekpartial-R2: 0.0sex, age, deprivation index, PC1-16
PPM017845PGS003497
(cont-decay-depressed_for_1w)
PSS010516|
South Asian Ancestry|
3,525 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Ever depressed for a whole weekpartial-R2: 0.0sex, age, deprivation index, PC1-16
PPM017929PGS003497
(cont-decay-depressed_for_1w)
PSS010432|
East Asian Ancestry|
751 individuals
PGP000457 |
Ding Y et al. bioRxiv (2022)
|Pre
Reported Trait: Ever depressed for a whole weekpartial-R2: 0.0sex, age, deprivation index, PC1-16
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Evaluated Samples

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PGS Sample Set ID
(PSS)
Phenotype Definitions and Methods
Participant Follow-up Time
Sample Numbers
Age of Study Participants
Sample Ancestry
Additional Ancestry Description
Cohort(s)
Additional Sample/Cohort Information
PSS007840215 individualsAfrican American or Afro-CaribbeanCarribeanUKB
PSS008053215 individualsEast AsianChina (East Asia)UKB
PSS008276425 individualsSouth AsianIndia (South Asia)UKB
PSS008498100 individualsGreater Middle Eastern (Middle Eastern, North African or Persian)Iran (Middle East)UKB
PSS0087241,364 individualsEuropeanItaly (South Europe)UKB
PSS008944214 individualsAfrican unspecifiedNigeria (West Africa)UKB
PSS009170741 individualsEuropeanPoland (NE Europe)UKB
PSS0093963,597 individualsEuropeanUK (+ Ireland)UKB
PSS010264593 individuals,
43.0 % Male samples
Mean = 58.7 years
Sd = 6.9 years
EuropeanAshkenaziUKB
PSS0103481,457 individuals,
37.0 % Male samples
Mean = 52.6 years
Sd = 7.9 years
African American or Afro-CaribbeanCaribbeanUKB
PSS010432751 individuals,
30.0 % Male samples
Mean = 53.5 years
Sd = 8.1 years
East AsianChineseUKB
PSS0105163,525 individuals,
53.0 % Male samples
Mean = 53.7 years
Sd = 8.5 years
South AsianIndianUKB
PSS010600505 individuals,
55.0 % Male samples
Mean = 53.4 years
Sd = 8.3 years
Greater Middle Eastern (Middle Eastern, North African or Persian)IranianUKB
PSS0106842,449 individuals,
43.0 % Male samples
Mean = 54.5 years
Sd = 8.7 years
EuropeanItalianUKB
PSS0107682,067 individuals,
42.0 % Male samples
Mean = 52.2 years
Sd = 8.0 years
African unspecifiedNigerianUKB
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