Trait: mosaic loss of chromosome Y measurement

Experimental Factor Ontology (EFO) Information
Identifier EFO_0007783
Trait category
Other measurement

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
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Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS003575
(mloy-PRS)
 PGP000460 |
García-González P et al. Int J Mol Sci (2023)
 Mosaic loss of chromosome Y mosaic loss of chromosome Y measurement 114
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003575/ScoringFiles/PGS003575.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM018177 PGS003575
(mloy-PRS)
 PSS010945|
European Ancestry|
2,286 individuals
 PGP000460 |
García-González P et al. Int J Mol Sci (2023)
 Reported Trait: Mosaic loss of chromosome Y in male aged 65-85 OR: 1.8 (1.07) — — — —
PPM018178 PGS003575
(mloy-PRS)
 PSS010945|
European Ancestry|
2,286 individuals
 PGP000460 |
García-González P et al. Int J Mol Sci (2023)
 Reported Trait: MCI-to-dementia progression in males HR: 1.11 (0.06) — — APOE genotype, age, and cohort ascertainment —
PPM018179 PGS003575
(mloy-PRS)
 PSS010945|
European Ancestry|
2,286 individuals
 PGP000460 |
García-González P et al. Int J Mol Sci (2023)
 Reported Trait: MCI-to-AD progression in males HR: 1.23 (0.08) — — APOE genotype, age, and cohort ascertainment —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS010945 — — 2,286 individuals — European — NR GR@ACE-DEGESCO