Trait: presubiculum volume

Experimental Factor Ontology (EFO) Information
Identifier EFO_0009400
Description Volume of subiculum region in hippocampus.
Trait category
Other measurement

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS003699
(L_presubiculum_head_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left presubiculum head volume presubiculum volume 13,044
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003699/ScoringFiles/PGS003699.txt.gz
PGS003700
(L_presubiculum_body_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left presubiculum body volume presubiculum volume 9,457
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003700/ScoringFiles/PGS003700.txt.gz
PGS003701
(R_presubiculum_head_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right presubiculum head volume presubiculum volume 4,398
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003701/ScoringFiles/PGS003701.txt.gz
PGS003702
(R_presubiculum_body_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right presubiculum body volume presubiculum volume 24,030
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003702/ScoringFiles/PGS003702.txt.gz
PGS003703
(L_presubiculum_head_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left presubiculum head volume presubiculum volume 13,326
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003703/ScoringFiles/PGS003703.txt.gz
PGS003704
(L_presubiculum_body_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left presubiculum body volume presubiculum volume 17,508
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003704/ScoringFiles/PGS003704.txt.gz
PGS003705
(R_presubiculum_head_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right presubiculum head volume presubiculum volume 98
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003705/ScoringFiles/PGS003705.txt.gz
PGS003706
(R_presubiculum_body_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right presubiculum body volume presubiculum volume 79,285
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003706/ScoringFiles/PGS003706.txt.gz
PGS003707
(L_presubiculum_head_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left presubiculum head volume presubiculum volume 33,663
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003707/ScoringFiles/PGS003707.txt.gz
PGS003708
(L_presubiculum_body_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left presubiculum body volume presubiculum volume 231
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003708/ScoringFiles/PGS003708.txt.gz
PGS003709
(R_presubiculum_head_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right presubiculum head volume presubiculum volume 40,964
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003709/ScoringFiles/PGS003709.txt.gz
PGS003710
(R_presubiculum_body_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right presubiculum body volume presubiculum volume 19,082
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003710/ScoringFiles/PGS003710.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM018292 PGS003699
(L_presubiculum_head_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left presubiculum head volume — — R²: 0.00774 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018294 PGS003700
(L_presubiculum_body_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left presubiculum body volume — — R²: 0.01031 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018313 PGS003701
(R_presubiculum_head_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right presubiculum head volume — — R²: 0.01692 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018315 PGS003702
(R_presubiculum_body_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right presubiculum body volume — — R²: 0.01907 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018336 PGS003703
(L_presubiculum_head_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left presubiculum head volume — — R²: 0.00478 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018338 PGS003704
(L_presubiculum_body_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left presubiculum body volume — — R²: 0.00397 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018357 PGS003705
(R_presubiculum_head_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right presubiculum head volume — — R²: 0.00577 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018359 PGS003706
(R_presubiculum_body_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right presubiculum body volume — — R²: 0.00626 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018380 PGS003707
(L_presubiculum_head_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left presubiculum head volume — — R²: 0.00603 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018382 PGS003708
(L_presubiculum_body_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left presubiculum body volume — — R²: 0.0049 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018401 PGS003709
(R_presubiculum_head_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right presubiculum head volume — — R²: 0.00299 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018403 PGS003710
(R_presubiculum_body_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right presubiculum body volume — — R²: 0.00551 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS010958 — — 1,999 individuals — East Asian — CHIMGEN —