Trait: hippocampal fissure volume

Experimental Factor Ontology (EFO) Information
Identifier EFO_0009404
Description Volume of hippocampal fissure volume.
Trait category
Other measurement

Associated Polygenic Score(s)

Filter PGS by Participant Ancestry
Individuals included in:
G - Source of Variant Associations (GWAS)
D - Score Development/Training
E - PGS Evaluation
List of ancestries includes:
Display options:
Ancestry legend
Multi-ancestry (including European)
Multi-ancestry (excluding European)
African
East Asian
South Asian
Additional Asian Ancestries
European
Greater Middle Eastern
Hispanic or Latin American
Additional Diverse Ancestries
Not Reported
Polygenic Score ID & Name PGS Publication ID (PGP) Reported Trait Mapped Trait(s) (Ontology) Number of Variants Ancestry distribution
GWAS
Dev
Eval
 Scoring File (FTP Link)
PGS003645
(L_hippocampal_fissure_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left hippocampal fissure volume hippocampal fissure volume 44,196
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003645/ScoringFiles/PGS003645.txt.gz
PGS003646
(R_hippocampal_fissure_trans_ancestry_meta_analysis)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right hippocampal fissure volume hippocampal fissure volume 3,822
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003646/ScoringFiles/PGS003646.txt.gz
PGS003647
(L_hippocampal_fissure_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left hippocampal fissure volume hippocampal fissure volume 6,350
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003647/ScoringFiles/PGS003647.txt.gz
PGS003648
(R_hippocampal_fissure_UKBB_EUR_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right hippocampal fissure volume hippocampal fissure volume 9,700
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003648/ScoringFiles/PGS003648.txt.gz
PGS003649
(L_hippocampal_fissure_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Left hippocampal fissure volume hippocampal fissure volume 115,071
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003649/ScoringFiles/PGS003649.txt.gz
PGS003650
(R_hippocampal_fissure_CHIMGEN_EAS_GWAS)
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Right hippocampal fissure volume hippocampal fissure volume 88,296
-
 https://ftp.ebi.ac.uk/pub/databases/spot/pgs/scores/PGS003650/ScoringFiles/PGS003650.txt.gz

Performance Metrics

Disclaimer: The performance metrics are displayed as reported by the source studies. It is important to note that metrics are not necessarily comparable with each other. For example, metrics depend on the sample characteristics (described by the PGS Catalog Sample Set [PSS] ID), phenotyping, and statistical modelling. Please refer to the source publication for additional guidance on performance.

PGS Performance
Metric ID (PPM) 		Evaluated Score PGS Sample Set ID
(PSS) 		Performance Source Trait PGS Effect Sizes
(per SD change) 		Classification Metrics Other Metrics Covariates Included in the Model PGS Performance:
Other Relevant Information
PPM018291 PGS003645
(L_hippocampal_fissure_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left hippocampal fissure volume — — R²: 0.00576 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018312 PGS003646
(R_hippocampal_fissure_trans_ancestry_meta_analysis)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right hippocampal fissure volume — — R²: 0.01456 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018335 PGS003647
(L_hippocampal_fissure_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left hippocampal fissure volume — — R²: 0.00568 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018356 PGS003648
(R_hippocampal_fissure_UKBB_EUR_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right hippocampal fissure volume — — R²: 0.00395 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018379 PGS003649
(L_hippocampal_fissure_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Left hippocampal fissure volume — — R²: 0.00272 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —
PPM018400 PGS003650
(R_hippocampal_fissure_CHIMGEN_EAS_GWAS)
 PSS010958|
East Asian Ancestry|
1,999 individuals
 PGP000464 |
Liu N et al. Nat Genet (2023)
 Reported Trait: Right hippocampal fissure volume — — R²: 0.00221 sex, age, age2, age × sex, total intracranial volume, and top six genetic principal components —

Evaluated Samples

PGS Sample Set ID
(PSS) 		Phenotype Definitions and Methods Participant Follow-up Time Sample Numbers Age of Study Participants Sample Ancestry Additional Ancestry Description Cohort(s) Additional Sample/Cohort Information
PSS010958 — — 1,999 individuals — East Asian — CHIMGEN —